Journal
NATURE CHEMISTRY
Volume 12, Issue 9, Pages 791-792Publisher
NATURE PUBLISHING GROUP
DOI: 10.1038/s41557-020-0533-1
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Enzymes that methylate usingS-adenosyl-l-methionine - nature's methyliodide - are abundant and often promiscuous; however, a preference for alkylation over methylation has been neither observed in nature nor engineered. Now, carboxymethylation has been demonstrated using engineered methyltransferases.
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