Journal
MULTIPLE SCLEROSIS JOURNAL
Volume 27, Issue 7, Pages 1136-1139Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/1352458520951382
Keywords
Multiple sclerosis; exercise; HIIT; NLR; inflammation; cellular inflammation marker; high-intensity interval exercise; rehabilitation
Categories
Funding
- Swiss Multiple Sclerosis Society
- Stiftung Ergotherapie
Ask authors/readers for more resources
The study indicates that high-intensity interval training (HIIT) can reduce the neutrophil-to-lymphocyte ratio (NLR) in patients with multiple sclerosis, possibly through repetitive inflammatory states and compensatory anti-inflammatory effects after each HIIT session.
In persons with multiple sclerosis (PwMS), the neutrophil-to-lymphocyte ratio (NLR) is associated with disability status, symptomatology and disease activity. High-intensity interval training (HIIT) improves many symptoms in PwMS and may positively influence disease progression. Here, we present results from a randomized controlled trial during inpatient rehabilitation on immediate (single bout) and training (3-week intervention) effects of HIIT versus moderate continuous training on NLR and related cellular inflammation markers. Only HIIT reduced the NLR over the 3-week intervention period. These training effects might be due to repetitive inflammatory states with compensatory anti-inflammatory counterbalancing after each HIIT session.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available