4.6 Article

Regulation of Anxiety and Depression by Mitochondrial Translocator Protein-Mediated Steroidogenesis: the Role of Neurons

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Neuronal activity increases translocator protein (TSPO) levels

Tina Notter et al.

Summary: The study found that neuronal activity can modify TSPO levels in the adult central nervous system. TSPO gene and protein are widely expressed in the hippocampus, but their levels increase only in neurons after stimulating neuronal activity, rather than in glial cells.

MOLECULAR PSYCHIATRY (2021)

Letter Biochemical Research Methods

Moving beyond P values: data analysis with estimation graphics

Joses Ho et al.

NATURE METHODS (2019)

Review Biochemistry & Molecular Biology

Reconceptualization of translocator protein as a biomarker of neuroinflammation in psychiatry

T. Notter et al.

MOLECULAR PSYCHIATRY (2018)

Article Behavioral Sciences

FGIN-1-27, an agonist at translocator protein 18 kDa (TSPO), produces anti-anxiety and anti-panic effects in non-mammalian models

Monica Gomes Lima-Maximino et al.

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2018)

Article Biochemistry & Molecular Biology

Cellular Sources and Regional Variations in the Expression of the Neuroinflammatory Marker Translocator Protein (TSPO) in the Normal Brain

Calina Betlazar et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Article Immunology

Assessment of neuroinflammation in a mouse model of obesity and β-amyloidosis using PET

Anna M. Barron et al.

JOURNAL OF NEUROINFLAMMATION (2016)

Article Clinical Neurology

Involvement of allopregnanolone in the anti-PTSD-like effects of AC-5216

Li-Ming Zhang et al.

JOURNAL OF PSYCHOPHARMACOLOGY (2016)

Article Multidisciplinary Sciences

The hGFAP-driven conditional TSPO knockout is protective in a mouse model of multiple sclerosis

Daniel J. Daugherty et al.

SCIENTIFIC REPORTS (2016)

Article Biochemistry & Molecular Biology

Identification of a Key Cholesterol Binding Enhancement Motif in Translocator Protein 18 kDa

Fei Li et al.

BIOCHEMISTRY (2015)

Article Endocrinology & Metabolism

PK11195 Effect on Steroidogenesis Is Not Mediated Through the Translocator Protein (TSPO)

Lan N. Tu et al.

ENDOCRINOLOGY (2015)

Article Multidisciplinary Sciences

Conditional steroidogenic cell-targeted deletion of TSPO unveils a crucial role in viability and hormone-dependent steroid formation

Jinjiang Fan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Review Neurosciences

The role of allopregnanolone in depression and anxiety

Cornelius Schuele et al.

PROGRESS IN NEUROBIOLOGY (2014)

Article Multidisciplinary Sciences

Structure of the Mitochondrial Translocator Protein in Complex with a Diagnostic Ligand

Lukasz Jaremko et al.

SCIENCE (2014)

Article Multidisciplinary Sciences

Positron emission tomography and functional characterization of a complete PBR/TSPO knockout

Richard B. Banati et al.

NATURE COMMUNICATIONS (2014)

Article Endocrinology & Metabolism

Bipolar Disorder is associated with the rs6971 polymorphism in the gene encoding 18 kDa Translocator Protein (TSPO)

Alessandro Colasanti et al.

PSYCHONEUROENDOCRINOLOGY (2013)

Review Clinical Neurology

Translocator protein (18 kDa) (TSPO) as a therapeutic target for anxiety and neurologic disorders

Caroline Nothdurfter et al.

EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE (2012)

Article Biochemistry & Molecular Biology

Regulation of synaptic plasticity by hippocampus synthesized estradiol

Anna M. Barron et al.

HORMONE MOLECULAR BIOLOGY AND CLINICAL INVESTIGATION (2011)

Review Biotechnology & Applied Microbiology

Translocator protein (18 kDa) (TSPO) as a therapeutic target for neurological and psychiatric disorders

Rainer Rupprecht et al.

NATURE REVIEWS DRUG DISCOVERY (2010)

Review Endocrinology & Metabolism

Neurosteroid biosynthesis: Enzymatic pathways and neuroendocrine regulation by neurotransmitters and neuropeptides

Jean Luc Do Rego et al.

FRONTIERS IN NEUROENDOCRINOLOGY (2009)

Article Neurosciences

Ro5-4864 promotes neonatal motor neuron survival and nerve regeneration in adult rats

Charles Mills et al.

EUROPEAN JOURNAL OF NEUROSCIENCE (2008)

Article Behavioral Sciences

Involvement of neurosteroids in the anxiolytic-like effects of AC-5216 in mice

Atsuko Kita et al.

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2008)

Article Multidisciplinary Sciences

Characterization of brain neurons that express enzymes mediating neurosteroid biosynthesis

Roberto C. Agis-Balboa et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)

Article Genetics & Heredity

Evidence that variation in the peripheral benzodiazepine receptor (PBR) gene influences susceptibility to panic disorder

K Nakamura et al.

AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2006)

Article Endocrinology & Metabolism

Local neurosteroid production in the hippocampus: Influence on synaptic plasticity of memory

Hideo Mukai et al.

NEUROENDOCRINOLOGY (2006)

Review Neurosciences

Neurosteroids:: Endogenous regulators of the GABAA receptor

D Belelli et al.

NATURE REVIEWS NEUROSCIENCE (2005)

Article Multidisciplinary Sciences

Adult male rat hippocampus synthesizes estradiol from pregnenolone by cytochromes P45017α and P450 aromatase localized in neurons

Y Hojo et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Review Endocrinology & Metabolism

Neuroactive steroids: mechanisms of action and neuropsychopharmacological properties

R Rupprecht

PSYCHONEUROENDOCRINOLOGY (2003)