Prevalence of low bone mass in individuals with HIV infection

Background and aims: There are no population data on bone mass in individuals with HIV in Spain, adjusted for age and sex. Materials and methods: Bone mineral density (BMD) data were obtained by dual X-ray absorptiometry in a cohort of individuals with HIV infection compared with cohort data from the general population in Spain and the United States of America. Results: Of 928 individuals (mean 46 years, 25% women), the prevalence of osteoporosis in the lumbar spine/femoral neck was 18%/5% in men, and 17%/10% in women, respectively. The rate increased from the age of 40 in men and from 50 in women (osteoporosis in 20% and 27%, respectively). BMD was lower than that observed in the general population in almost all age groups (mean, -6%; between 0%-11% lower compared to the Spanish cohort, and -8%; between 0%-14% lower than the American cohort). Conclusions: Our cohort of individuals with HIV had a lower BMD in all age groups after adjustment for age and sex, compared with the general population. This fact must be considered when making recommendations. (C) 2020 Elsevier Espana, S.L.U. All rights reserved.

Automated summary

A study on bone mass in individuals with HIV in Spain showed that this population had lower bone mineral density compared to the general population in almost all age groups. This finding needs to be considered when making recommendations.