Starch nanofibers as vehicles for folic acid supplementation: thermal treatment,UVAirradiation andin vitrosimulation of digestion

BACKGROUND The supplementation of folic acid in food is essential in the human diet. The present study aimed to encapsulate folic acid at different concentrations (5, 10 and 15% (w/w) on a dry basis) in potato starch nanofibers produced through electrospinning. The starch/folic acid nanofibers were evaluated through morphology, Fourier transform infrared (FTIR) spectra, thermal properties, encapsulation efficiency (EE) andin vitrosimulation of the human digestion. The nanofibers were also evaluated based on the folic acid content after thermal treatment (100 and 180 degrees C) and UVA irradiation (1 and 24 h). RESULTS Folic acid incorporation influenced the morphology of the nanofibers to display a homogeneous and beadless morphology for nanofibers containing 15% folic acid compared with the other nanofibers (0, 5 and 10% folic acid). The mean diameter varied from 75 to 81 nm. Folic acid characteristic bands and peaks were not found in the nanofiber FTIR spectra and thermograms, respectively. The EE was 73, 87 and 95% for nanofibers with 5, 10 and 15% folic acid, respectively. CONCLUSIONS The starch nanofibers protected folic acid from high temperature and UVA irradiation and duringin vitrodigestion, showing a release of the vitamin at the end of the simulation (intestinal conditions). The supplementation of folic acid in foods can be effectively achieved by its encapsulation into starch nanofibers, to ensure its protection and controlled release. (c) 2020 Society of Chemical Industry

Automated summary

The encapsulation of folic acid in starch nanofibers can improve morphology and encapsulation efficiency, as well as protect folic acid from high temperature and UVA irradiation.