An effective process for the synthesis of dihydropyridines viaSO4-2/SnO2-catalyzed Hantzsch reaction

Sulfated tin oxide (STO) was established as an admirable heterogeneous catalyst for the single-step synthesis of dihydropyridine derivatives via Hantzsch reaction. The synthetic method was mainly used in the presence of STO as a heterogeneous solid catalyst. STO-catalyzed Hantzsch reaction afforded good yields (90-94%) in acetonitrile at 80 degrees C. The synthesized titled compounds were characterized and confirmed by High Resolution Mass Spectroscopy (HRMS), Fourier Tranform-Infrared (FTIR),H-1 and(13)C-NMR, and spectral data.

Automated summary

Sulfated tin oxide (STO) was established as an excellent heterogeneous catalyst for the single-step synthesis of dihydropyridine derivatives via Hantzsch reaction, achieving good yields (90-94%). The synthesized compounds were characterized and confirmed using various spectroscopic techniques.