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Mental health outcomes of coronavirus infection survivors: A rapid meta-analysis

Journal

JOURNAL OF PSYCHIATRIC RESEARCH
Volume 137, Issue -, Pages 542-553

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.jpsychires.2020.10.015

Keywords

Coronavirus; SARS; Mental health; Meta-analysis

Categories

Funding

  1. fund for building world-class universities (disciplines) of Renmin University of China [KYGJA2020001]
  2. Journalism Research Center, Renmin University of China [RMXW2018A005]

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The study found that the adverse mental health impact of being hospitalized with coronavirus infection long outlasts the physical illness, but there was significant improvement during the first 12 months after hospital discharge, with slow continuous improvement thereafter.
Background: The current COVID pandemic is happening while the long-term effects of coronavirus infection remain poorly understood. The present article meta-analyzed mental health outcomes (anxiety, depression, etc.) from a previous coronavirus outbreak in China (2002). Method: CNKI, Wanfang, PubMed/Medline, Scopus, Web of Science, Baidu Scholar, and Google Scholar were searched up to early June 2020 for articles in English or Chinese reporting mental illness symptoms of SARS patients. Main outcome measures include SCL-90, SAS, SDS, and IES-R scales. 29 papers met the inclusion criteria. The longest follow-up time included in the analysis was 46 months. Findings: The systematic meta-analysis indicated that mental health problems were most serious before or at hospital discharge and declined significantly during the first 12 months after hospital discharge. Nevertheless, average symptom levels remained above healthy norms even at 12 months and continued to improve, albeit slowly, thereafter. Interpretation: The adverse mental health impact of being hospitalized with coronavirus infection long outlasts the physical illness. Mental health issues were the most serious for coronavirus infected patients before (including) hospital discharge and improved continuously during the first 12 months after hospital discharge. If COVID-19 infected patients follow a similar course of mental health development, most patients should recover to normal after 12 months of hospital discharge.

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