Journal
JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
Volume 188, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.jpba.2020.113465
Keywords
Turmeric (Curcuma longaL.); Quality control; HPLC; GC/MS
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Funding
- National Key Research and Development Program of China [2017YFC1700405]
- National Administration of Traditional Chinese Medicine [ZYBZHY-GD-13/ZYY-2017-108]
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Turmeric (Curcuma longa L.) is a popular herbal medicine worldwide. Curcuminoids and volatile constituents are its major bioactive components. To improve the quality control of turmeric, we determined the contents of three main curcuminoids in 160 batches of turmeric samples collected from five major production areas of China by HPLC, and analyzed the volatile components by GC/MS. The results indicated that samples with red cross sections (2.75 +/- 0.82 mg/g) contained significantly higher amounts of curcuminoids than samples with yellow sections (1.23 +/- 0.60 mg/g) (p < 0.001). This result was consistent with empirical standard of TCM pharmacists. The contents of curcuminoids in samples from Hainan (4.51 +/- 0.25%), Guizhou (3.17 +/- 0.41%), and Sichuan (2.25 +/- 0.54%) were relatively high and consistent. Moreover, the GC/MS profiles of turmeric may be affected by storage and processing. This study sets a good example for comprehensive quality control of herbal medicines. (C) 2020 Published by Elsevier B.V.
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