Journal
JOURNAL OF INFECTIOUS DISEASES
Volume 223, Issue 11, Pages 1948-1952Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/infdis/jiaa650
Keywords
malaria; Democratic Republic of the Congo; adolescents; Plasmodium falciparum
Categories
Funding
- National Institute for Allergy and Infectious Disease, National Institutes of Health [T32AI070114, F30AI143172, K01AI125087, R01AI107949]
- Burroughs Wellcome Fund-American Society for Tropical Medicine and Hygiene
- Carolina Population Center [T32 HD007168, P2C HD050924]
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The research found that previous surveys often overlooked the higher burden of malaria in older children and adolescents, whereas in fact, this age group had the highest prevalence of the disease.
Despite evidence that older children and adolescents bear the highest burden of malaria, large malaria surveys focus on younger children. We used polymerase chain reaction data from the 2013-2014 Demographic and Health Survey in the Democratic Republic of Congo (including children aged <5 years and adults aged >= 15 years) and a longitudinal study in Kinshasa Province (participants aged 6 months to 98 years) to estimate malaria prevalence across age strata. We fit linear models and estimated prevalences for each age category; adolescents aged 10-14 years had the highest prevalence. We estimate approximately 26 million polymerase chain reaction-detectable infections nationally. Adolescents and older children should be included in surveillance studies.
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