Related references
Note: Only part of the references are listed.CRISPR-engineered T cells in patients with refractory cancer
Edward A. Stadtmauer et al.
SCIENCE (2020)
Neoantigens in Hematologic Malignancies
Melinda A. Biernacki et al.
FRONTIERS IN IMMUNOLOGY (2020)
Single-Cell RNA-Seq Reveals AML Hierarchies Relevant to Disease Progression and Immunity
Peter van Galen et al.
CELL (2019)
Immunogenic neoantigens derived from gene fusions stimulate T cell responses
Wei Yang et al.
NATURE MEDICINE (2019)
Gene editing for immune cell therapies
Stefanie R. Bailey et al.
NATURE BIOTECHNOLOGY (2019)
T cell receptor gene therapy targeting WT1 prevents acute myeloid leukemia relapse post-transplant
Aude G. Chapuis et al.
NATURE MEDICINE (2019)
Acute myeloid leukemia immunopeptidome reveals HLA presentation of mutated nucleophosmin
Rupa Narayan et al.
PLOS ONE (2019)
Pediatric patients with acute lymphoblastic leukemia generate abundant and functional neoantigen-specific CD8+ T cell responses
Anthony E. Zamora et al.
SCIENCE TRANSLATIONAL MEDICINE (2019)
Neoantigen quality, not quantity
Nicholas McGranahan et al.
SCIENCE TRANSLATIONAL MEDICINE (2019)
Developing neoantigen-targeted T cell-based treatments for solid tumors
Tori N. Yamamoto et al.
NATURE MEDICINE (2019)
Mutated nucleophosmin 1 as immunotherapy target in acute myeloid leukemia
Dyantha van der Lee et al.
JOURNAL OF CLINICAL INVESTIGATION (2019)
Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial
Derin B. Keskin et al.
NATURE (2019)
A highly efficient and faithful MDS patient-derived xenotransplantation model for pre-clinical studies
Yuanbin Song et al.
NATURE COMMUNICATIONS (2019)
The molecular landscape of pediatric acute myeloid leukemia reveals recurrent structural alterations and age-specific mutational interactions
Hamid Bolouri et al.
NATURE MEDICINE (2018)
Chimeric antigen receptor-modified T cells: CD19 and the road beyond
Alexander I. Salter et al.
BLOOD (2018)
Clonal interference of signaling mutations worsens prognosis in core-binding factor acute myeloid leukemia
Raphael Itzykson et al.
BLOOD (2018)
Tumor-infiltrating BRAF(V600E)-specific CD4(+) T cells correlated with complete clinical response in melanoma
Joshua R. Veatch et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Immune recognition of somatic mutations leading to complete durable regression in metastatic breast cancer
Nikolaos Zacharakis et al.
NATURE MEDICINE (2018)
Reprogramming human T cell function and specificity with non-viral genome targeting
Theodore L. Roth et al.
NATURE (2018)
Acquired cancer resistance to combination immunotherapy from transcriptional loss of class I HLA
K. G. Paulson et al.
NATURE COMMUNICATIONS (2018)
Efficient and Non-genotoxic RNA-Based Engineering of Human T Cells Using Tumor-Specific T Cell Receptors With Minimal TCR Mispairing
Diana Campillo-Davo et al.
FRONTIERS IN IMMUNOLOGY (2018)
Development of T-cell immunotherapy for hematopoietic stem cell transplantation recipients at risk of leukemia relapse
Robson G. Dossa et al.
BLOOD (2018)
Ten-year outcome of patients with acute myeloid leukemia not treated with allogeneic transplantation in first complete remission
Sumithira Vasu et al.
BLOOD ADVANCES (2018)
Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel
Hartmut Doehner et al.
BLOOD (2017)
NetMHCpan-4.0: Improved Peptide-MHC Class I Interaction Predictions Integrating Eluted Ligand and Peptide Binding Affinity Data
Vanessa Jurtz et al.
JOURNAL OF IMMUNOLOGY (2017)
Personalized RNA mutanome vaccines mobilize poly-specific therapeutic immunity against cancer
Ugur Sahin et al.
NATURE (2017)
An immunogenic personal neoantigen vaccine for patients with melanoma
Patrick A. Ott et al.
NATURE (2017)
In situ programming of leukaemia-specific T cells using synthetic DNA nanocarriers
Tyrel T. Smith et al.
NATURE NANOTECHNOLOGY (2017)
Targeting neoantigens to augment antitumour immunity
Mark Yarchoan et al.
NATURE REVIEWS CANCER (2017)
Gapped sequence alignment using artificial neural networks: application to the MHC class I system
Massimo Andreatta et al.
BIOINFORMATICS (2016)
Somatic mutational landscape of AML with inv(16) or t(8;21) identifies patterns of clonal evolution in relapse leukemia
R. Sood et al.
LEUKEMIA (2016)
Chimeric antigen receptor-modified T cells derived from defined CD8+ and CD4+ subsets confer superior antitumor reactivity in vivo
D. Sommermeyer et al.
LEUKEMIA (2016)
inv(16) and NPM1mut AMLs engraft human cytokine knock-in mice
Jana M. Ellegast et al.
BLOOD (2016)
Peripheral blood CD34+ cells efficiently engraft human cytokine knock-in mice
Yasuyuki Saito et al.
BLOOD (2016)
The genomic landscape of core-binding factor acute myeloid leukemias
Zachary J. Faber et al.
NATURE GENETICS (2016)
Prospective identification of neoantigen-specific lymphocytes in the peripheral blood of melanoma patients
Alena Gros et al.
NATURE MEDICINE (2016)
T-Cell Transfer Therapy Targeting Mutant KRAS in Cancer
Eric Tran et al.
NEW ENGLAND JOURNAL OF MEDICINE (2016)
Targeting of cancer neoantigens with donor-derived T cell receptor repertoires
Erlend Stronen et al.
SCIENCE (2016)
Exposure to Melan-A/MART-126-35 tumor epitope specific CD8+ T cells reveals immune escape by affecting the ubiquitin-proteasome system (UPS)
Frederic Ebstein et al.
SCIENTIFIC REPORTS (2016)
NetMHCpan-3.0; improved prediction of binding to MHC class I molecules integrating information from multiple receptor and peptide length datasets
Morten Nielsen et al.
GENOME MEDICINE (2016)
Immunogenicity of somatic mutations in human gastrointestinal cancers
Eric Tran et al.
SCIENCE (2015)
Expression of indoleamine 2,3-dioxygenase in leukemic cells indicates an unfavorable prognosis in acute myeloid leukemia patients with intermediate-risk cytogenetics
Kenji Fukuno et al.
LEUKEMIA & LYMPHOMA (2015)
A highly compact epitope-based marker/suicide gene for easier and safer T-cell therapy
Brian Philip et al.
BLOOD (2014)
OKT3 prevents xenogeneic GVHD and allows reliable xenograft initiation from unfractionated human hematopoietic tissues
Mark Wunderlich et al.
BLOOD (2014)
Systematic identification of personal tumor-specific neoantigens in chronic lymphocytic leukemia
Mohini Rajasagi et al.
BLOOD (2014)
Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing
Mahesh Yadav et al.
NATURE (2014)
Development and function of human innate immune cells in a humanized mouse model
Anthony Rongvaux et al.
NATURE BIOTECHNOLOGY (2014)
Tumour antigens recognized by T lymphocytes: at the core of cancer immunotherapy
Pierre G. Coulie et al.
NATURE REVIEWS CANCER (2014)
Clonal evolution and devolution after chemotherapy in adult acute myelogenous leukemia
Brian Parkin et al.
BLOOD (2013)
Acute myeloid leukemia creates an arginase-dependent immunosuppressive microenvironment
Francis Mussai et al.
BLOOD (2013)
Immune responses against the mutated region of cytoplasmatic NPM1 might contribute to the favorable clinical outcome of AML patients with NPM1 mutations (NPM1mut)
Jochen Greiner et al.
BLOOD (2013)
Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells
Paul F. Robbins et al.
NATURE MEDICINE (2013)
KIT with D816 mutations cooperates with CBFB-MYH11 for leukemogenesis in mice
Ling Zhao et al.
BLOOD (2012)
Mapping of novel peptides of WT-1 and presenting HLA alleles that induce epitope-specific HLA-restricted T cells with cytotoxic activity against WT-1+ leukemias
Ekaterina Doubrovina et al.
BLOOD (2012)
Minimal residual disease monitoring by quantitative RT-PCR in core binding factor AML allows risk stratification and predicts relapse: results of the United Kingdom MRC AML-15 trial
John A. Liu Yin et al.
BLOOD (2012)
Immune epitope database analysis resource
Yohan Kim et al.
NUCLEIC ACIDS RESEARCH (2012)
The only proposed T-cell epitope derived from the TEL-AML1 translocation is not naturally processed
Jelena Popovic et al.
BLOOD (2011)
Prophylactic transfer of BCR-ABL-, PR1-, and WT1-reactive donor T cells after T cell-depleted allogeneic hematopoietic cell transplantation in patients with chronic myeloid leukemia
Martin Bornhaeuser et al.
BLOOD (2011)
Inducible Apoptosis as a Safety Switch for Adoptive Cell Therapy
Antonio Di Stasi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Leukemia-associated minor histocompatibility antigen discovery using T-cell clones isolated by in vitro stimulation of naive CD8+ T cells
Marie Bleakley et al.
BLOOD (2010)
Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials
David Grimwade et al.
BLOOD (2010)
PD-1/PD-L1 interactions inhibit antitumor immune responses in a murine acute myeloid leukemia model
Long Zhang et al.
BLOOD (2009)
NetMHCpan, a method for MHC class I binding prediction beyond humans
Ilka Hoof et al.
IMMUNOGENETICS (2009)
Tracking epitope-specific T cells
James J. Moon et al.
NATURE PROTOCOLS (2009)
NetMHC-3.0: accurate web accessible predictions of human, mouse and monkey MHC class I affinities for peptides of length 8-11
Claus Lundegaard et al.
NUCLEIC ACIDS RESEARCH (2008)
Rare CBFB-MYH11 fusion transcripts in AML with inv(16)/t(16;16) are associated with therapy-related AML M4eo, atypical cytomorphology, atypical immunophenotype, atypical additional chromosomal rearrangements and low white blood cell count:: a study on 162 patients
S. Schnittger et al.
LEUKEMIA (2007)
Gene transfer of tumor-reactive TCR confers both high avidity and tumor reactivity to nonreactive peripheral blood mononuclear cells and tumor-infiltrating lymphocytes
Laura A. Johnson et al.
JOURNAL OF IMMUNOLOGY (2006)
The clinical spectrum of adult acute myeloid leukaemia associated with core binding factor translocations
Frederick R. Appelbaum et al.
BRITISH JOURNAL OF HAEMATOLOGY (2006)
Identification and epitope enhancement of a PAX-FKHR fusion protein breakpoint epitope in alveolar rhabdomyosarcoma cells created by a tumorigenic chromosomal translocation inducing CTL capable of lysing human tumors
LT van den Broeke et al.
CANCER RESEARCH (2006)
Cbf beta-SMMHC induces distinct abnormal myeloid progenitors able to develop acute myeloid leukemia
YH Kuo et al.
CANCER CELL (2006)
Development of a human adaptive immune system in cord blood cell-transplanted mice
E Traggiai et al.
SCIENCE (2004)
New CFSE-based assay to determine susceptibility to lysis by cytotoxic T cells of leukemic precursor cells within a heterogeneous target cell population
I Jedema et al.
BLOOD (2004)
High avidity antigen-specific CTL identified by CD8-independent tetramer staining
EML Choi et al.
JOURNAL OF IMMUNOLOGY (2003)
Prenatal origin of childhood acute myeloid leukemias harboring chromosomal rearrangements t(15;17) and inv(16)
CM McHale et al.
BLOOD (2003)
Reliable prediction of T-cell epitopes using neural networks with novel sequence representations
M Nielsen et al.
PROTEIN SCIENCE (2003)
Identification of a novel HLA-B60-restricted T cell epitope of the minor histocompatibility antigen HA-1 locus
B Mommaas et al.
JOURNAL OF IMMUNOLOGY (2002)
Core-binding factors in haematopoiesis and leukaemia
NA Speck et al.
NATURE REVIEWS CANCER (2002)
Microenvironment produced by acute myeloid leukemia cells prevents T cell activation and proliferation by inhibition of NF-κB, c-myc, and pRb pathways
AGS Buggins et al.
JOURNAL OF IMMUNOLOGY (2001)
Direct evidence that leukemic cells present HLA-associated immunogenic peptides derived from the BCR-ABL b3a2 fusion protein
RE Clark et al.
BLOOD (2001)