Related references
Note: Only part of the references are listed.Adenosine 2A Receptor Blockade as an Immunotherapy for Treatment-Refractory Renal Cell Cancer
Lawrence Fong et al.
CANCER DISCOVERY (2020)
Current issues and perspectives in PD-1 blockade cancer immunotherapy
Kenji Chamoto et al.
INTERNATIONAL JOURNAL OF CLINICAL ONCOLOGY (2020)
Lessons from the A2A Adenosine Receptor Antagonist-Enabled Tumor Regression and Survival in Patients with Treatment-Refractory Renal Cell Cancer
Michail V. Sitkovsky
CANCER DISCOVERY (2020)
The importance of exosomal PDL1 in tumour immune evasion
Dhouha Daassi et al.
NATURE REVIEWS IMMUNOLOGY (2020)
CD8+ T cell states in human cancer: insights from single-cell analysis
Anne M. Van der Leun et al.
NATURE REVIEWS CANCER (2020)
Hypoxia-inducible factors in CD4+ T cells promote metabolism, switch cytokine secretion, and T cell help in humoral immunity
Sung Hoon Cho et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
Pharmacologic Targeting of Hypoxia-Inducible Factors
Gregg L. Semenza
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 59 (2019)
A2A Adenosine Receptor Gene Deletion or Synthetic A2A Antagonist Liberate Tumor-Reactive CD8+ T Cells from Tumor-Induced Immunosuppression
Jorgen Kjaergaard et al.
JOURNAL OF IMMUNOLOGY (2018)
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
Jie Lan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Fundamental Mechanisms of Immune Checkpoint Blockade Therapy
Spencer C. Wei et al.
CANCER DISCOVERY (2018)
A2AR Antagonism with CPI-444 Induces Antitumor Responses and Augments Efficacy to Anti-PD-(L)1 and Anti-CTLA-4 in Preclinical Models
Stephen B. Willingham et al.
CANCER IMMUNOLOGY RESEARCH (2018)
Targeted hypoxia reduction restores T cell infiltration and sensitizes prostate cancer to immunotherapy
Priyamvada Jayaprakash et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Targeting the adenosine 2A receptor enhances chimeric antigen receptor T cell efficacy
Paul A. Beavis et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
The EGLN-HIF O2-Sensing System: Multiple Inputs and Feedbacks
Mircea Ivan et al.
MOLECULAR CELL (2017)
Hypoxia and hypoxia-inducible factor (HIF) downregulate antigen-presenting MHC class I molecules limiting tumor cell recognition by T cells
Shalini Sethumadhavan et al.
PLOS ONE (2017)
An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression
Asis Palazon et al.
CANCER CELL (2017)
Co-inhibition of CD73 and A2AR Adenosine Signaling Improves Anti-tumor Immune Responses
Arabella Young et al.
CANCER CELL (2016)
The Basis of Oncoimmunology
A. Karolina Palucka et al.
CELL (2016)
Germinal Center Hypoxia Potentiates Immunoglobulin Class Switch Recombination
Robert K. Abbott et al.
JOURNAL OF IMMUNOLOGY (2016)
Germinal centre hypoxia and regulation of antibody qualities by a hypoxia response system
Sung Hoon Cho et al.
NATURE (2016)
Protein kinase A-dependent phosphorylation stimulates the transcriptional activity of hypoxia-inducible factor 1
John W. Bullen et al.
SCIENCE SIGNALING (2016)
Protein kinase A-dependent phosphorylation stimulates the transcriptional activity of hypoxia-inducible factor 1
John W. Bullen et al.
SCIENCE SIGNALING (2016)
Hypoxia-Inducible Factors: Master Regulators of Cancer Progression
Luana Schito et al.
TRENDS IN CANCER (2016)
Immunological mechanisms of the antitumor effects of supplemental oxygenation
Stephen M. Hatfield et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
Adenosine Receptor 2A Blockade Increases the Efficacy of Anti-PD-1 through Enhanced Antitumor T-cell Responses
Paul A. Beavis et al.
CANCER IMMUNOLOGY RESEARCH (2015)
Oxygenation to improve cancer vaccines, adoptive cell transfer and blockade of immunological negative regulators
Stephen M. Hatfield et al.
ONCOIMMUNOLOGY (2015)
Postoperative Hyperoxia (60%) Worsens Hepatic Injury in Mice
Quirin Zangl et al.
ANESTHESIOLOGY (2014)
Hypoxia-induced and A2A adenosine receptor-independent T-cell suppression is short lived and easily reversible
Akio Ohta et al.
INTERNATIONAL IMMUNOLOGY (2014)
Systemic oxygenation weakens the hypoxia and hypoxia inducible factor 1α-dependent and extracellular adenosine-mediated tumor protection
Stephen M. Hatfield et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2014)
Hostile, Hypoxia-A2-Adenosinergic Tumor Biology as the Next Barrier to Overcome for Tumor Immunologists
Michail V. Sitkovsky et al.
CANCER IMMUNOLOGY RESEARCH (2014)
Genetic deletion of the HIF-1α isoform I.1 in T cells enhances antibacterial immunity and improves survival in a murine peritonitis model
Peter Georgiev et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2013)
Targeting the hypoxia-adenosinergic signaling pathway to improve the adoptive immunotherapy of cancer
Michail Sitkovsky et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2013)
Adenosine receptors as drug targets - what are the challenges?
Jiang-Fan Chen et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
Purinergic Signaling during Inflammation
Chung-Jen Chen et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
CD73 promotes anthracycline resistance and poor prognosis in triple negative breast cancer
Sherene Loi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Blockade of A2A receptors potently suppresses the metastasis of CD73+ tumors
Paul A. Beavis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
A2A blockade enhances anti-metastatic immune responses
Paul A. Beavis et al.
ONCOIMMUNOLOGY (2013)
Immunity, inflammation and cancer: a leading role for adenosine
Luca Antonioli et al.
NATURE REVIEWS CANCER (2013)
Enhancement of tumor immunotherapy by deletion of the A2A adenosine receptor
Adam T. Waickman et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2012)
Inhibitors of hypoxia-inducible factor 1 block breast cancer metastatic niche formation and lung metastasis
Carmen Chak-Lui Wong et al.
JOURNAL OF MOLECULAR MEDICINE-JMM (2012)
In Vivo Hypoxic Preconditioning Protects From Warm Liver Ischemia-Reperfusion Injury Through the Adenosine A2B Receptor
Alexander Chouker et al.
TRANSPLANTATION (2012)
In vivo T cell activation in lymphoid tissues is inhibited in the oxygen-poor microenvironment
Akio Ohta et al.
FRONTIERS IN IMMUNOLOGY (2011)
CD73 on Tumor Cells Impairs Antitumor T-Cell Responses: A Novel Mechanism of Tumor-Induced Immune Suppression
Dachuan Jin et al.
CANCER RESEARCH (2010)
CD39/ENTPD1 Expression by CD4+Foxp3+ Regulatory T Cells Promotes Hepatic Metastatic Tumor Growth in Mice
Xiaofeng Sun et al.
GASTROENTEROLOGY (2010)
Differentiation Stage-Specific Requirement in Hypoxia-Inducible Factor-1 alpha-Regulated Glycolytic Pathway during Murine B Cell Development in Bone Marrow
Hidefumi Kojima et al.
JOURNAL OF IMMUNOLOGY (2010)
Anti-CD73 antibody therapy inhibits breast tumor growth and metastasis
John Stagg et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
In vitro induction of T cells that are resistant to A(2) adenosine receptor-mediated immunosuppression
Akio Ohta et al.
BRITISH JOURNAL OF PHARMACOLOGY (2009)
Differential regulation of HIF-1α isoforms in murine macrophages by TLR4 and adenosine A2A receptor agonists
Madhuri Ramanathan et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2009)
T regulatory cells: hypoxia-adenosinergic suppression and re-direction of the immune response
Michail V. Sitkovsky
TRENDS IN IMMUNOLOGY (2009)
Hypoxia-Adenosinergic Immunosuppression: Tumor Protection by T Regulatory Cells and Cancerous Tissue Hypoxia
Michail V. Sitkovsky et al.
CLINICAL CANCER RESEARCH (2008)
Preferential expression of the novel alternative isoform I.3 of hypoxia-inducible factor lot in activated human T lymphocytes
Dmitriy Lukashev et al.
HUMAN IMMUNOLOGY (2008)
Critical role of hypoxia and A2A adenosine receptors in liver tissue-protecting physiological anti-inflammatory pathway
Alexander Chouker et al.
MOLECULAR MEDICINE (2008)
Cycling hypoxia and free radicals regulate angiogenesis and radiotherapy response
Mark W. Dewhirst et al.
NATURE REVIEWS CANCER (2008)
Sphingosine-1-phosphate reduces CD4+ T-cell activation in type 1 diabetes through regulation of hypoxia-inducible factor short isoform I.1 and CD69
Suseela Srinivasan et al.
DIABETES (2008)
A(2A) receptor signaling promotes peripheral tolerance by inducing T-cell anergy and the generation of adaptive regulatory T cells
Paul E. Zarek et al.
BLOOD (2008)
Adoptive cell transfer: a clinical path to effective cancer immunotherapy
Steven A. Rosenberg et al.
NATURE REVIEWS CANCER (2008)
Targeted Deletion of HIF-1α Gene in T Cells Prevents their Inhibition in Hypoxic Inflamed Tissues and Improves Septic Mice Survival
Manfred Thiel et al.
PLOS ONE (2007)
Contribution of E-NTPDase1 (CD39) to renal protection from ischemia-reperfusion injury
Almut Grenz et al.
FASEB JOURNAL (2007)
Identification of ectonucleotidases CD39 and CD73 in innate protection during acute lung injury
Tobias Eckle et al.
JOURNAL OF IMMUNOLOGY (2007)
Hypoxia-dependent anti-inflammatory pathways in protection of cancerous tissues
D. Lukashev et al.
CANCER AND METASTASIS REVIEWS (2007)
Cutting edge:: Hypoxia-inducible factor 1α and its activation-inducible short isoform I.1 negatively regulate functions of CD4+ and CD8+ T lymphocytes
Dmitriy Lukashev et al.
JOURNAL OF IMMUNOLOGY (2006)
A2A adenosine receptor protects tumors from antitumor T cells
Akio Ohta et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Oxygenation inhibits the physiological tissue-protecting mechanism and thereby exacerbates acute inflammatory lung injury
M Thiel et al.
PLOS BIOLOGY (2005)
Regulation of immune cells by local. tissue oxygen tension: Hif1 alpha and adenosine receptors
M Sitkovsky et al.
NATURE REVIEWS IMMUNOLOGY (2005)
Physiological control of immune response and inflammatory tissue damage by hypoxia-inducible factors and adenosine A(2A) receptors
MV Sitkovsky et al.
ANNUAL REVIEW OF IMMUNOLOGY (2004)
Abnormal B lymphocyte development and autoimmunity in hypoxia-inducible factor 1α-deficient chimeric mice
H Kojima et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Differential regulation of two alternatively spliced isoforms of hypoxia-inducible factor-1α in activated T lymphocytes
D Lukashev et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Role of G-protein-coupled adenosine receptors in downregulation of inflammation and protection from tissue damage
A Ohta et al.
NATURE (2001)
Differential effects of physiologically relevant hypoxic conditions on T lymphocyte development and effector functions
CC Caldwell et al.
JOURNAL OF IMMUNOLOGY (2001)
Share Paper
