Journal
JOURNAL OF ALZHEIMERS DISEASE
Volume 78, Issue 2, Pages 537-541Publisher
IOS PRESS
DOI: 10.3233/JAD-200940
Keywords
Alzheimer's disease; care homes; COVID-19; frontotemporal dementia; SARS-CoV-2
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We aimed to evaluate the frequency and mortality of COVID-19 in patients with Alzheimer's disease (AD) and frontotemporal dementia (FTD). We conducted an observational case series. We enrolled 204 patients, 15.2% of whom were diagnosed with COVID-19, and 41.9% of patients with the infection died. Patients with AD were older than patients with FTD (80.36 +/- 8.77 versus 72.00 +/- 8.35 years old) and had a higher prevalence of arterial hypertension (55.8% versus 26.3%). COVID-19 occurred in 7.3% of patients living at home, but 72.0% of those living at care homes. Living in care facilities and diagnosis of AD were independently associated with a higher probability of death. We found that living in care homes is the most relevant factor for an increased risk of COVID-19 infection and death, with AD patients exhibiting a higher risk than those with FTD.
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