Journal
INTERNATIONAL JOURNAL OF STD & AIDS
Volume 31, Issue 14, Pages 1407-1410Publisher
SAGE PUBLICATIONS LTD
DOI: 10.1177/0956462420955075
Keywords
HIV; integrase strand transfer inhibitor; dolutegravir; adipose tissue density; weight gain
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Integrase strand transfer inhibitors (INSTIs) are a class of antiretroviral drugs with high virologic efficacy and excellent tolerability. Recent evidence showed a possible link of dolutegravir-based regimens with weight gain, and a relationship between raltegravir use and changes in adipose tissue density and metabolic abnormalities, with an increased cardiovascular risk, has been suggested. We describe a case where dolutegravir monotherapy led to a decrease in adipose tissue density.
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