Journal
INTERNATIONAL JOURNAL OF POLYMERIC MATERIALS AND POLYMERIC BIOMATERIALS
Volume 71, Issue 5, Pages 315-335Publisher
TAYLOR & FRANCIS AS
DOI: 10.1080/00914037.2020.1833010
Keywords
Shape-memory polymers; alloys; clinical applications; tissue engineering; drug delivery
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Shape-memory materials offer unconventional functions in materials science and have significant potential for biomedical applications. However, their long-term biocompatibility for permanent applications remains a critical issue.
Shape-memory characteristics shed light on materials science and open horizons for accessing to unconventional functions in material categories subsuming metals, polymers, and ceramics. Biomedical fields manifest great interest in adopting shape-memory materials for unconventional properties, specifications, and well-defined mechanical properties. In spite of the mentioned advantages, their biocompatibility for long-term and permanent applications has not yet been comprehensively distinguished. This article summarizes the most common clinical applications of shape memory alloys and polymers, e.g., tissue engineering, drug delivery, hydrogels, orthodontic wires/distracters, artificial discs, orthopedic staples, atrial septal occlusion devices, neurosurgical stents, etc., and also addresses their critical biocompatibility issues.
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