Related references
Note: Only part of the references are listed.Proteomics in cerebrospinal fluid and spinal cord suggests UCHL1, MAP2 and GPNMB as biomarkers and underpins importance of transcriptional pathways in amyotrophic lateral sclerosis
Patrick Deckl et al.
ACTA NEUROPATHOLOGICA (2020)
Microglial regional heterogeneity and its role in the brain
Yun-Long Tan et al.
MOLECULAR PSYCHIATRY (2020)
Endocannabinoid Modulation of Microglial Phenotypes in Neuropathology
Mikiei Tanaka et al.
FRONTIERS IN NEUROLOGY (2020)
Moving Toward Multicenter Therapeutic Trials in Amyotrophic Lateral Sclerosis: Feasibility of Data Pooling Using Different Translocator Protein PET Radioligands
Donatienne Van Weehaeghe et al.
JOURNAL OF NUCLEAR MEDICINE (2020)
Amyotrophic lateral sclerosis: a clinical review
P. Masrori et al.
EUROPEAN JOURNAL OF NEUROLOGY (2020)
11C-PK11195 PET-based molecular study of microglia activation in SOD1 amyotrophic lateral sclerosis
Giacomo Tondo et al.
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2020)
Diagnostic and Prognostic Value of Conventional Brain MRI in the Clinical Work-Up of Patients with Amyotrophic Lateral Sclerosis
Giovanni Rizzo et al.
JOURNAL OF CLINICAL MEDICINE (2020)
Motor cortex transcriptome reveals microglial key events in amyotrophic lateral sclerosis
Oriol Dols-Icardo et al.
NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION (2020)
The role of glia in protein aggregation
Qingyun Li et al.
NEUROBIOLOGY OF DISEASE (2020)
Structural MRI outcomes and predictors of disease progression in amyotrophic lateral sclerosis
Edoardo G. Spinelli et al.
NEUROIMAGE-CLINICAL (2020)
TREM2 Variants and Neurodegenerative Diseases: A Systematic Review and Meta-Analysis
Sheng-Lan Zhou et al.
JOURNAL OF ALZHEIMERS DISEASE (2019)
Slide-seq: A scalable technology for measuring genome-wide expression at high spatial resolution
Samuel G. Rodriques et al.
SCIENCE (2019)
Spatiotemporal dynamics of molecular pathology in amyotrophic lateral sclerosis
Silas Maniatis et al.
SCIENCE (2019)
The Major Risk Factors for Alzheimer's Disease: Age, Sex, and Genes Modulate the Microglia Response to Aβ Plaques
Carlo Sala Frigerio et al.
CELL REPORTS (2019)
Effects of Neurotrophic Factors in Glial Cells in the Central Nervous System: Expression and Properties in Neurodegeneration and Injury
Suvi Poyhonen et al.
FRONTIERS IN PHYSIOLOGY (2019)
Unbiased MRI Analyses Identify Micropathologic Differences Between Upper Motor Neuron-Predominant ALS Phenotypes
Venkateswaran Rajagopalan et al.
FRONTIERS IN NEUROSCIENCE (2019)
Upregulation of cannabinoid receptor type 2, but not TSPO, in senescence-accelerated neuroinflammation in mice: a positron emission tomography study
Satoru Yamagishi et al.
JOURNAL OF NEUROINFLAMMATION (2019)
Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes
Timothy R. Hammond et al.
IMMUNITY (2019)
Human microglia regional heterogeneity and phenotypes determined by multiplexed single-cell mass cytometry
Chotima Boettcher et al.
NATURE NEUROSCIENCE (2019)
Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing
Qingyun Li et al.
NEURON (2019)
Structure-Activity Relationship Studies of Pyridine-Based Ligands and Identification of a Fluorinated Derivative for Positron Emission Tomography Imaging of Cannabinoid Type 2 Receptors
Ahmed Haider et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
Nucleo-cytoplasmic transport of TDP-43 studied in real time: impaired microglia function leads to axonal spreading of TDP-43 in degenerating motor neurons
Adam J. Svahn et al.
ACTA NEUROPATHOLOGICA (2018)
NF-κB activation in astrocytes drives a stage-specific beneficial neuroimmunological response in ALS
Najwa Ouali Alami et al.
EMBO JOURNAL (2018)
Microglia-mediated recovery from ALS-relevant motor neuron degeneration in a mouse model of TDP-43 proteinopathy
Krista J. Spiller et al.
NATURE NEUROSCIENCE (2018)
Single-cell mass cytometry reveals distinct populations of brain myeloid cells in mouse neuroinflammation and neurodegeneration models
Bahareh Ajami et al.
NATURE NEUROSCIENCE (2018)
Genome-wide Analyses Identify KIF5A as a Novel ALS Gene
Aude Nicolas et al.
NEURON (2018)
Microglia in Alzheimer's Disease: Activated, Dysfunctional or Degenerative
Victoria Navarro et al.
FRONTIERS IN AGING NEUROSCIENCE (2018)
Imaging of glia activation in people with primary lateral sclerosis
Sabrina Paganoni et al.
NEUROIMAGE-CLINICAL (2018)
Activation of the Immune-Metabolic Receptor GPR84 Enhances Inflammation and Phagocytosis in Macrophages
Carlota Recio et al.
FRONTIERS IN IMMUNOLOGY (2018)
Molecular Diversity and Specializations among the Cells of the Adult Mouse Brain
Arpiar Saunders et al.
CELL (2018)
Single-cell transcriptomics reveals distinct inflammation-induced microglia signatures
Carole Sousa et al.
EMBO REPORTS (2018)
Integrated imaging of [11C]-PBR28 PET, MR diffusion and magnetic resonance spectroscopy 1H-MRS in amyotrophic lateral sclerosis
Eva-Maria Ratai et al.
NEUROIMAGE-CLINICAL (2018)
Characterization of 11C-GSK1482160 for Targeting the P2X7 Receptor as a Biomarker for Neuroinflammation
Paul R. Territo et al.
JOURNAL OF NUCLEAR MEDICINE (2017)
Comparative Evaluation of Three TSPO PET Radiotracers in a LPS-Induced Model of Mild Neuroinflammation in Rats
Sujata Sridharan et al.
MOLECULAR IMAGING AND BIOLOGY (2017)
The TREM2-APOE Pathway Drives the Transcriptional Phenotype of Dysfunctional Microglia in Neurodegenerative Diseases
Susanne Krasemann et al.
IMMUNITY (2017)
Neurodegenerative diseases: The immunological perspective
Monica Molteni et al.
JOURNAL OF NEUROIMMUNOLOGY (2017)
In vivo TSPO and cannabinoid receptor type 2 availability early in post-stroke neuroinflammation in rats: a positron emission tomography study
Teruyo Hosoya et al.
JOURNAL OF NEUROINFLAMMATION (2017)
Evidence for an early innate immune response in the motor cortex of ALS
Javier H. Jara et al.
JOURNAL OF NEUROINFLAMMATION (2017)
Resolving Astrocyte Heterogeneity in the CNS
W. Todd Farmer et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2017)
The Dual Role of Microglia in ALS: Mechanisms and Therapeutic Approaches
Maria Concetta Geloso et al.
FRONTIERS IN AGING NEUROSCIENCE (2017)
Palmitoylethanolamide induces microglia changes associated with increased migration and phagocytic activity: involvement of the CB2 receptor
F. Guida et al.
SCIENTIFIC REPORTS (2017)
A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease
Hadas Keren-Shaul et al.
CELL (2017)
Mitochondria-associated membranes as hubs for neurodegeneration
Michiel Krols et al.
ACTA NEUROPATHOLOGICA (2016)
TSPO: kaleidoscopic 18-kDa amid biochemical pharmacology, control and targeting of mitochondria
Jemma Gatliff et al.
BIOCHEMICAL JOURNAL (2016)
Imaging of brain TSPO expression in a mouse model of amyotrophic lateral sclerosis with 18F-DPA-714 and micro-PET/CT
S. Gargiulo et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2016)
Development of a High-Affinity PET Radioligand for Imaging Cannabinoid Subtype 2 Receptor
Rares-Petru Moldovan et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Origin, fate and dynamics of macrophages at central nervous system interfaces
Tobias Goldmann et al.
NATURE IMMUNOLOGY (2016)
New tools for studying microglia in the mouse and human CNS
Mariko L. Bennett et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Oligodendrocyte heterogeneity in the mouse juvenile and adult central nervous system
Sueli Marques et al.
SCIENCE (2016)
Visualization and analysis of gene expression in tissue sections by spatial transcriptomics
Patrik L. Stahl et al.
SCIENCE (2016)
CB2 Cannabinoid Receptor Knockout in Mice Impairs Contextual Long-Term Memory and Enhances Spatial Working Memory
Yong Li et al.
NEURAL PLASTICITY (2016)
Magnetic susceptibility in the deep layers of the primary motor cortex in Amyotrophic Lateral Sclerosis
M. Costagli et al.
NEUROIMAGE-CLINICAL (2016)
Activation of murine microglial N9 cells is attenuated through cannabinoid receptor CB2 signaling
Lei Ma et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2015)
TREM2 Lipid Sensing Sustains the Microglial Response in an Alzheimer's Disease Model
Yaming Wang et al.
CELL (2015)
Synthesis, radiolabeling and evaluation of novel 4-oxo-quinoline derivatives as PET tracers for imaging cannabinoid type 2 receptor
Roger Slavik et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2015)
Discovery of a High Affinity and Selective Pyridine Analog as a Potential Positron Emission Tomography Imaging Agent for Cannabinoid Type 2 Receptor
Roger Slavik et al.
JOURNAL OF MEDICINAL CHEMISTRY (2015)
Changes in the endocannabinoid signaling system in CNS structures of TDP-43 transgenic mice: relevance for a neuroprotective therapy in TDP-43-related disorders
Francisco Espejo-Porras et al.
JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2015)
In Vivo Detection of Age- and Disease-Related Increases in Neuroinflammation by 18F-GE180 TSPO MicroPET Imaging in Wild-Type and Alzheimer's Transgenic Mice
Bin Liu et al.
JOURNAL OF NEUROSCIENCE (2015)
Chronic activation of CB2 cannabinoid receptors in the hippocampus increases excitatory synaptic transmission
Jimok Kim et al.
JOURNAL OF PHYSIOLOGY-LONDON (2015)
Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq
Amit Zeisel et al.
SCIENCE (2015)
Astrocyte-Derived TGF-β1 Accelerates Disease Progression in ALS Mice by Interfering with the Neuroprotective Functions of Microglia and T Cells
Fumito Endo et al.
CELL REPORTS (2015)
Anandamide, Acting via CB2 Receptors, Alleviates LPS-Induced Neuroinflammation in Rat Primary Microglial Cultures
Natalia Malek et al.
NEURAL PLASTICITY (2015)
Increased in vivo glial activation in patients with amyotrophic lateral sclerosis: Assessed with [C-11]-PBR28
Nicole R. Zuercher et al.
NEUROIMAGE-CLINICAL (2015)
Induction of a common microglia gene expression signature by aging and neurodegenerative conditions: a co-expression meta-analysis
Inge R. Holtman et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2015)
Targeting miR-155 Restores Abnormal Microglia and Attenuates Disease in SOD1 Mice
Oleg Butovsky et al.
ANNALS OF NEUROLOGY (2015)
18F-GE-180: a novel TSPO radiotracer compared to 11C-R-PK11195 in a preclinical model of stroke
Herve Boutin et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2015)
Cannabinoid CB2 Receptors in a Mouse Model of Aβ Amyloidosis: Immunohistochemical Analysis and Suitability as a PET Biomarker of Neuroinflammation
Alena V. Savonenko et al.
PLOS ONE (2015)
Regulatory role of the cannabinoid CB2 receptor in stress- induced neuroinflammation in mice
S. Zoppi et al.
BRITISH JOURNAL OF PHARMACOLOGY (2014)
Development and Evaluation of Novel PET Tracers for Imaging Cannabinoid Receptor Type 2 in Brain
Roger Slavik et al.
CHIMIA (2014)
Spinal cord pathology is ameliorated by P2X7 antagonism in a SOD1-mutant mouse model of amyotrophic lateral sclerosis
Savina Apolloni et al.
DISEASE MODELS & MECHANISMS (2014)
Bridging the gap: Membrane contact sites in signaling, metabolism, and organelle dynamics
William A. Prinz
JOURNAL OF CELL BIOLOGY (2014)
Identification of a unique TGF-β dependent molecular and functional signature in microglia
Oleg Butovsky et al.
NATURE NEUROSCIENCE (2014)
Brain fluorodeoxyglucose PET in adrenoleukodystrophy
Ettore Salsano et al.
NEUROLOGY (2014)
Microglia Induce Motor Neuron Death via the Classical NF-κB Pathway in Amyotrophic Lateral Sclerosis
Ashley E. Frakes et al.
NEURON (2014)
Exosome-dependent and independent mechanisms are involved in prion-like transmission of propagated Cu/Zn superoxide dismutase misfolding
Leslie I. Grad et al.
PRION (2014)
Microglia centered pathogenesis in ALS: insights in cell interconnectivity
Dora Brites et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2014)
Method for widespread microRNA-155 inhibition prolongs survival in ALS-model mice
Erica D. Koval et al.
HUMAN MOLECULAR GENETICS (2013)
Whole-Body Biodistribution and Radiation Dosimetry of the Cannabinoid Type 2 Receptor Ligand [11C]-NE40 in Healthy Subjects
Rawaha Ahmad et al.
MOLECULAR IMAGING AND BIOLOGY (2013)
[18 F]DPA-714: Direct Comparison with [11C]PK11195 in a Model of Cerebral Ischemia in Rats
Herve Boutin et al.
PLOS ONE (2013)
Cannabinoid Receptor CB2 Modulates Axon Guidance
Gabriel Duff et al.
PLOS ONE (2013)
Dysregulated microRNAs in amyotrophic lateral sclerosis microglia modulate genes linked to neuroinflammation
C. Parisi et al.
CELL DEATH & DISEASE (2013)
A Neurodegeneration-Specific Gene-Expression Signature of Acutely Isolated Microglia from an Amyotrophic Lateral Sclerosis Mouse Model
Isaac M. Chiu et al.
CELL REPORTS (2013)
Wnt3a induces exosome secretion from primary cultured rat microglia
Claudie Hooper et al.
BMC NEUROSCIENCE (2012)
Structural and Functional Evolution of the Translocator Protein (18 kDa)
J. Fan et al.
CURRENT MOLECULAR MEDICINE (2012)
CB2 Cannabinoid Receptors Promote Neural Progenitor Cell Proliferation via mTORC1 Signaling
Javier Palazuelos et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
An 18-kDa Translocator Protein (TSPO) polymorphism explains differences in binding affinity of the PET radioligand PBR28
David R. Owen et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2012)
Modulating inflammatory monocytes with a unique microRNA gene signature ameliorates murine ALS
Oleg Butovsky et al.
JOURNAL OF CLINICAL INVESTIGATION (2012)
Reactive Astrocytes Overexpress TSPO and Are Detected by TSPO Positron Emission Tomography Imaging
Sonia Lavisse et al.
JOURNAL OF NEUROSCIENCE (2012)
Lipopolysaccharide-Induced Microglial Activation and Neuroprotection against Experimental Brain Injury Is Independent of Hematogenous TLR4
Zhihong Chen et al.
JOURNAL OF NEUROSCIENCE (2012)
Endocannabinoid Signaling and Synaptic Function
Pablo E. Castillo et al.
NEURON (2012)
Preclinical evaluation of [11C]NE40, a type 2 cannabinoid receptor PET tracer
Nele Evens et al.
NUCLEAR MEDICINE AND BIOLOGY (2012)
Molecular Imaging of Microglial Activation in Amyotrophic Lateral Sclerosis
Philippe Corcia et al.
PLOS ONE (2012)
Emerging roles of exosomes in neuron-glia communication
Carsten Fruehbeis et al.
FRONTIERS IN PHYSIOLOGY (2012)
Microglial microvesicle secretion and intercellular signaling
Elena Turola et al.
FRONTIERS IN PHYSIOLOGY (2012)
Transmembrane tumour necrosis factor is neuroprotective and regulates experimental autoimmune encephalomyelitis via neuronal nuclear factor-κB
Era Taoufik et al.
BRAIN (2011)
Relationship between neuropathology and disease progression in the SOD1G93A ALS mouse
Wendy W. Yang et al.
EXPERIMENTAL NEUROLOGY (2011)
Treatment with minocycline after disease onset alters astrocyte reactivity and increases microgliosis in SOD1 mutant mice
A. Florence Keller et al.
EXPERIMENTAL NEUROLOGY (2011)
Deregulation of TDP-43 in amyotrophic lateral sclerosis triggers nuclear factor κB-mediated pathogenic pathways
Vivek Swarup et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Astrocytes from familial and sporadic ALS patients are toxic to motor neurons
Amanda M. Haidet-Phillips et al.
NATURE BIOTECHNOLOGY (2011)
Astroglial Inhibition of NF-κB Does Not Ameliorate Disease Onset and Progression in a Mouse Model for Amyotrophic Lateral Sclerosis (ALS)
Claudia Crosio et al.
PLOS ONE (2011)
Synthesis and biodistribution of [11C] A-836339, a new potential radioligand for PET imaging of cannabinoid type 2 receptors (CB2)
Andrew G. Horti et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2010)
Microglia in ALS: The Good, The Bad, and The Resting
Jenny S. Henkel et al.
JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2009)
PK11195 labels activated microglia in Alzheimer's disease and in vivo in a mouse model using PET
Sriram Venneti et al.
NEUROBIOLOGY OF AGING (2009)
Monitoring disease evolution and treatment response in lysosomal disorders by the peripheral benzodiazepine receptor ligand PK11195
Ilaria Visigalli et al.
NEUROBIOLOGY OF DISEASE (2009)
The positron emission tomography ligand DAA1106 binds with high affinity to activated microglia in human neurological disorders
Sriram Venneti et al.
JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2008)
DPA-714, a new translocator protein-specific ligand: Synthesis, radiofluorination, and pharmacologic characterization
Michelle L. James et al.
JOURNAL OF NUCLEAR MEDICINE (2008)
Translocator protein 18 kDa (TSPO): Molecular sensor of brain injury and repair
Ming-Kai Chen et al.
PHARMACOLOGY & THERAPEUTICS (2008)
G protein-coupled receptor 84, a microglia-associated protein expressed in neuroinflammatory conditions
Caroline Bouchard et al.
GLIA (2007)
The CB2 cannabinoid agonist AM-1241 prolongs survival in a transgenic mouse model of amyotrophic lateral sclerosis when initiated at symptom onset
Jennifer L. Shoemaker et al.
JOURNAL OF NEUROCHEMISTRY (2007)
The role of the cannabinoid CB2 receptor in pain transmission and therapeutic potential of small molecule CB2 receptor agonists
G. T. Whiteside et al.
CURRENT MEDICINAL CHEMISTRY (2007)
Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis
David R. Beers et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
The inflammatory NADPH oxidase enzyme modulates motor neuron degeneration in amyotrophic lateral sclerosis mice
Du-Chu Wu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Onset and progression in inherited ALS determined by motor neurons and microglia
Severine Boillee et al.
SCIENCE (2006)
NF-κB regulates spatial memory formation and synaptic plasticity through protein kinase A/CREB signaling
B Kaltschmidt et al.
MOLECULAR AND CELLULAR BIOLOGY (2006)
COX-2, CB2 and P2X7-immunoreactivities are increased in activated microglial cells/macrophages of multiple sclerosis and amyotrophic lateral sclerosis spinal cord
Y Yiangou et al.
BMC NEUROLOGY (2006)
Proteomic analysis of microglia-derived exosomes: Metabolic role of the aminopeptidase CD13 in neuropeptide catabolism
A Potolicchio et al.
JOURNAL OF IMMUNOLOGY (2005)
NF-κB signalling regulates the growth of neural processes in the developing PNS and CNS
H Gutierrez et al.
DEVELOPMENT (2005)
Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis:: an [11C](R)-PK11195 positron emission tomography study
MR Turner et al.
NEUROBIOLOGY OF DISEASE (2004)
Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue
JS Henkel et al.
ANNALS OF NEUROLOGY (2004)
Wild-type nonneuronal cells extend survival of SOD1 mutant motor neurons in ALS mice
AM Clement et al.
SCIENCE (2003)
Inhibition of NF-kB renders cells more vulnerable to apoptosis induced by amyloid β peptides
SM Cardoso et al.
FREE RADICAL RESEARCH (2003)
Nonpsychotropic cannabinoid receptors regulate microglial cell migration
L Walter et al.
JOURNAL OF NEUROSCIENCE (2003)
Motoneuron death triggered by a specific pathway downstream of Fas:: Potentiation by ALS-linked SOD1 mutations
C Raoul et al.
NEURON (2002)
Minocycline delays disease onset and mortality in a transgenic model of ALS
L Van Den Bosch et al.
NEUROREPORT (2002)
Share Paper
