Related references
Note: Only part of the references are listed.Pharmacology of the ATM Inhibitor AZD0156: Potentiation of Irradiation and Olaparib Responses Preclinically
Lucy C. Riches et al.
MOLECULAR CANCER THERAPEUTICS (2020)
Targeting DNA repair in cancer: current state and novel approaches
Apostolos Klinakis et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2020)
The impact of PARPs and ADP-ribosylation on inflammation and host-pathogen interactions
Anthony R. Fehr et al.
GENES & DEVELOPMENT (2020)
Targeting DNA-PK in cancer
Giovanna Damia
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2020)
Homologous Recombination Repair Deficiency and the Immune Response in Breast Cancer: A Literature Review
B. Pellegrino et al.
TRANSLATIONAL ONCOLOGY (2020)
The Cytosolic DNA-Sensing cGAS-STING Pathway in Cancer
John Kwon et al.
CANCER DISCOVERY (2020)
Immunomodulatory Roles of PARP-1 and PARP-2: Impact on PARP-Centered Cancer Therapies
Jose Yelamos et al.
CANCERS (2020)
CHK1 Inhibition Is Synthetically Lethal with Loss of B-Family DNA Polymerase Function in Human Lung and Colorectal Cancer Cells
Rebecca F. Rogers et al.
CANCER RESEARCH (2020)
The forefront of ovarian cancer therapy: update on PARP inhibitors
M. R. Mirza et al.
ANNALS OF ONCOLOGY (2020)
Modulation of immune responses using adjuvants to facilitate therapeutic vaccination
Virgil Schijns et al.
IMMUNOLOGICAL REVIEWS (2020)
Asbestos-related diseases
A. W. Musk et al.
INTERNATIONAL JOURNAL OF TUBERCULOSIS AND LUNG DISEASE (2020)
Using whole-genome sequencing data to derive the homologous recombination deficiency scores
Xavier M. de Luca et al.
NPJ BREAST CANCER (2020)
cGAS-STING, an important pathway in cancer immunotherapy
Minlin Jiang et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2020)
Is DNA repair a potential target for effective therapies against malignant mesothelioma?
Ilaria Fuso Nerini et al.
CANCER TREATMENT REVIEWS (2020)
Poly(ADP-ribosyl)ation by PARP1: reaction mechanism and regulatory proteins
Elizaveta E. Alemasova et al.
NUCLEIC ACIDS RESEARCH (2019)
Pharmacological Modulation of the STING Pathway for Cancer Immunotherapy
Gilles Berger et al.
TRENDS IN MOLECULAR MEDICINE (2019)
Research Progress on PARP14 as a Drug Target
Wei Qin et al.
FRONTIERS IN PHARMACOLOGY (2019)
Coordinated signals from the DNA repair enzymes PARP-1 and PARP-2 promotes B-cell development and function
Miguel A. Galindo-Campos et al.
CELL DEATH AND DIFFERENTIATION (2019)
Ataxia telangiectasia and Rad3-related inhibitors and cancer therapy: where we stand
Lin Mei et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2019)
PARP-1 inhibition provides protection against elastase-induced emphysema by mitigating the expression of matrix metalloproteinases
Vivek Dharwal et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2019)
DNA repair and neurological disease: From molecular understanding to the development of diagnostics and model organisms
Arwa A. Abugable et al.
DNA REPAIR (2019)
DNA double-strand break repair-pathway choice in somatic mammalian cells
Ralph Scully et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)
DNA Damage and Associated DNA Repair Defects in Disease and Premature Aging
Vinod Tiwari et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2019)
STING: a master regulator in the cancer-immunity cycle
Yuanyuan Zhu et al.
MOLECULAR CANCER (2019)
DNA damage responses in ageing
Paulo F. L. da Silva et al.
OPEN BIOLOGY (2019)
The cGAS Paradox: Contrasting Roles for cGAS-STING Pathway in Chromosomal Instability
Christy Hong et al.
CELLS (2019)
Chronic inflammation: key player and biomarker-set to predict and prevent cancer development and progression based on individualized patient profiles
Shehua Qian et al.
EPMA JOURNAL (2019)
State-of-the-art strategies for targeting the DNA damage response in cancer
Patrick G. Pilie et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2019)
Chronic inflammation in the etiology of disease across the life span
David Furman et al.
NATURE MEDICINE (2019)
Photoimmunology: how ultraviolet radiation affects the immune system
Jamie J. Bernard et al.
NATURE REVIEWS IMMUNOLOGY (2019)
Genetically engineered T cells for cancer immunotherapy
Dan Li et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2019)
Colorectal carcinoma in the course of inflammatory bowel diseases
Andrzej Hnatyszyn et al.
HEREDITARY CANCER IN CLINICAL PRACTICE (2019)
BRCA Genes: The Role in Genome Stability, Cancer Sternness and Therapy Resistance
Ielizaveta Gorodetska et al.
JOURNAL OF CANCER (2019)
Microhomology-mediated end joining: Good, bad and ugly
Ja-Hwan Seol et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2018)
PARP1 and PARP2 stabilise replication forks at base excision repair intermediates through Fbh1-dependent Rad51 regulation
George E. Ronson et al.
NATURE COMMUNICATIONS (2018)
Role of BRCA Mutations in the Modulation of Response to Platinum Therapy
Sanghamitra Mylavarapu et al.
FRONTIERS IN ONCOLOGY (2018)
Isocitrate dehydrogenase 2 deficiency induces endothelial inflammation via p66sh-mediated mitochondrial oxidative stress
Su-jeong Choi et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)
Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage
Gillian Dunphy et al.
MOLECULAR CELL (2018)
Trabectedin and olaparib in patients with advanced and non-resectable bone and soft-tissue sarcomas (TOMAS): an open-label, phase 1b study from the Italian Sarcoma Group
Giovanni Grignani et al.
LANCET ONCOLOGY (2018)
Immune and Inflammatory-Mediated Disorders: From Bench to Bedside
Marcella Reale et al.
JOURNAL OF IMMUNOLOGY RESEARCH (2018)
Carcinogens and DNA damage
Jessica L. Barnes et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2018)
Radiotherapy and immune response: the systemic effects of a local treatmentY
Heloisa de Andrade Carvalho et al.
CLINICS (2018)
Roles of the immune system in cancer: from tumor initiation to metastatic progression
Hugo Gonzalez et al.
GENES & DEVELOPMENT (2018)
Tryptophan Photoproduct FICZ Upregulates IL1A, IL1B, and IL6 Expression via Oxidative Stress in Keratinocytes
Yuka Tanaka et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2018)
PARP Inhibition Elicits STING-Dependent Antitumor Immunity in Brca1-Deficient Ovarian Cancer
Liya Ding et al.
CELL REPORTS (2018)
Mitochondria, Oxidative Stress and Innate Immunity
Yuxin Chen et al.
FRONTIERS IN PHYSIOLOGY (2018)
Opportunities for the repurposing of PARP inhibitors for the therapy of non-oncological diseases
Nathan A. Berger et al.
BRITISH JOURNAL OF PHARMACOLOGY (2018)
Microhomology-mediated end joining is activated in irradiated human cells due to phosphorylation-dependent formation of the XRCC1 repair complex
Arijit Dutta et al.
NUCLEIC ACIDS RESEARCH (2017)
Oxidative DNA damage & repair: An introduction
Jean Cadet et al.
FREE RADICAL BIOLOGY AND MEDICINE (2017)
Sensing of dangerous DNA
Stephan Gasser et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2017)
Inactivation of DNA repair triggers neoantigen generation and impairs tumour growth
Giovanni Germano et al.
NATURE (2017)
The multifaceted roles of PARP1 in DNA repair and chromatin remodelling
Arnab Ray Chaudhuri et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)
DNA damage and neurodegeneration: the unusual suspect
Daniel Stein et al.
NEURAL REGENERATION RESEARCH (2017)
Molecular mechanisms by which oxidative DNA damage promotes telomerase activity
Hui-Ting Lee et al.
NUCLEIC ACIDS RESEARCH (2017)
Mismatch repair deficiency predicts response of solid tumors to PD-1 blockade
Dung T. Le et al.
SCIENCE (2017)
Modulating Both Tumor Cell Death and Innate Immunity Is Essential for Improving Radiation Therapy Effectiveness
Qiuji Wu et al.
FRONTIERS IN IMMUNOLOGY (2017)
cGAS is activated by DNA in a length-dependent manner
Stefanie Luecke et al.
EMBO REPORTS (2017)
PARP Inhibitor Upregulates PD-L1 Expression and Enhances Cancer-Associated Immunosuppression
Shiping Jiao et al.
CLINICAL CANCER RESEARCH (2017)
Immunogenic cell death in cancer and infectious disease
Lorenzo Galluzzi et al.
NATURE REVIEWS IMMUNOLOGY (2017)
Key Characteristics of Carcinogens as a Basis for Organizing Data on Mechanisms of Carcinogenesis
Martyn T. Smith et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2016)
Cellular response to DNA interstrand crosslinks: the Fanconi anemia pathway
David Lopez-Martinez et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2016)
Nuclear Innate Immune DNA Sensor IFI16 Is Degraded during Lytic Reactivation of Kaposi's Sarcoma-Associated Herpesvirus (KSHV): Role of IFI16 in Maintenance of KSHV Latency
Arunava Roy et al.
JOURNAL OF VIROLOGY (2016)
PARP1 Links CHD2-Mediated Chromatin Expansion and H3.3 Deposition to DNA Repair by Non-homologous End-Joining
Martijn S. Luijsterburg et al.
MOLECULAR CELL (2016)
The nature of mutations induced by replication-transcription collisions
T. Sabari Sankar et al.
NATURE (2016)
ROS and ROS-Mediated Cellular Signaling
Jixiang Zhang et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2016)
UV and ionizing radiations induced DNA damage, differences and similarities
Jean-Luc Ravanat et al.
RADIATION PHYSICS AND CHEMISTRY (2016)
Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
Nicholas McGranahan et al.
SCIENCE (2016)
Regulation of Single-Strand Annealing and its Role in Genome Maintenance
Ragini Bhargava et al.
TRENDS IN GENETICS (2016)
AHR Function in Lymphocytes: Emerging Concepts
Liang Zhou
TRENDS IN IMMUNOLOGY (2016)
PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation
Hiroshi Iwata et al.
NATURE COMMUNICATIONS (2016)
Carcinogenic polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53-dependent mechanism
Laura E. Wohak et al.
ARCHIVES OF TOXICOLOGY (2016)
Self-regulation and cross-regulation of pattern-recognition receptor signalling in health and disease
Xuetao Cao
NATURE REVIEWS IMMUNOLOGY (2016)
ZBP1/DAI is an innate sensor of influenza virus triggering the NLRP3 inflammasome and programmed cell death pathways
Teneema Kuriakose et al.
SCIENCE IMMUNOLOGY (2016)
Connecting the Dots: From DNA Damage and Repair to Aging
Mei-Ren Pan et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)
The DNA Damage Response: Implications for Tumor Responses to Radiation and Chemotherapy
Michael Goldstein et al.
ANNUAL REVIEW OF MEDICINE, VOL 66 (2015)
DNA Replication Stress as a Hallmark of Cancer
Morgane Macheret et al.
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 10 (2015)
DNA Damage in Cancer Therapeutics: A Boon or a Curse?
Anchit Khanna
CANCER RESEARCH (2015)
Malignant mesothelioma as an oxidative stress-induced cancer: An update
Shan Hwu Chew et al.
FREE RADICAL BIOLOGY AND MEDICINE (2015)
Mitochondrial Oxidative Stress, Mitochondrial DNA Damage and Their Role in Age-Related Vascular Dysfunction
Yuliya Mikhed et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
Activation of the Arylhydrocarbon Receptor Causes immunosuppression Primarily by Modulating Dendritic Cells
Anika Bruhs et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2015)
R loops: new modulators of genome dynamics and function
Jose M. Santos-Pereira et al.
NATURE REVIEWS GENETICS (2015)
Neoantigens in cancer immunotherapy
Ton N. Schumacher et al.
SCIENCE (2015)
Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
Naiyer A. Rizvi et al.
SCIENCE (2015)
Reactive oxygen species a double-edged sword for mesothelioma
Serena Benedetti et al.
ONCOTARGET (2015)
Detection of coding microsatellite frameshift mutations in DNA mismatch repair-deficient mouse intestinal tumors
Stefan M. Woerner et al.
MOLECULAR CARCINOGENESIS (2015)
The Aryl Hydrocarbon Receptor in Barrier Organ Physiology, Immunology, and Toxicology
Charlotte Esser et al.
PHARMACOLOGICAL REVIEWS (2015)
Innate Immune Sensors Stimulate Inflammatory and Immunosuppressive Responses to UVB Radiation
Richard L. Gallo et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2014)
An essential role for platelet-activating factor in activating mast cell migration following ultraviolet irradiation
Rommel Chacon-Salinas et al.
JOURNAL OF LEUKOCYTE BIOLOGY (2014)
Chronic Inflammation (Inflammaging) and Its Potential Contribution to Age-Associated Diseases
Claudio Franceschi et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2014)
Transcription-Coupled Nucleotide Excision Repair Factors Promote R-Loop-Induced Genome Instability
Julie Sollier et al.
MOLECULAR CELL (2014)
The cGAS-cGAMP-STING Pathway of Cytosolic DNA Sensing and Signaling
Xin Cai et al.
MOLECULAR CELL (2014)
Causes and consequences of replication stress
Michelle K. Zeman et al.
NATURE CELL BIOLOGY (2014)
The causes of replication stress and their consequences on genome stability and cell fate
Indiana Magdalou et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2014)
Toll-like receptor signaling pathways
Takumi Kawasaki et al.
FRONTIERS IN IMMUNOLOGY (2014)
Immunogenic Cell Death in Cancer Therapy
Guido Kroemer et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 31 (2013)
Chromatin Remodeling at DNA Double-Strand Breaks
Brendan D. Price et al.
CELL (2013)
DNA Damage Triggers a Chronic Autoinflammatory Response, Leading to Fat Depletion in NER Progeria
Ismene Karakasilioti et al.
CELL METABOLISM (2013)
DNA-Damaging Agents in Cancer Chemotherapy: Serendipity and Chemical Biology
Kahlin Cheung-Ong et al.
CHEMISTRY & BIOLOGY (2013)
Beyond DNA repair, the immunological role of PARP-1 and its siblings
Maria Manuela Rosado et al.
IMMUNOLOGY (2013)
Human Cytochrome P450 1A1 Structure and Utility in Understanding Drug and Xenobiotic Metabolism
Agnes A. Walsh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Cellular senescence and the senescent secretory phenotype: therapeutic opportunities
Tamara Tchkonia et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
PARP-1 Inhibitor, DPQ, Attenuates LPS-Induced Acute Lung Injury through Inhibiting NF-κB-Mediated Inflammatory Response
Gang Wang et al.
PLOS ONE (2013)
Role of poly(ADP-ribose) polymerase-1 in the removal of UV-induced DNA lesions by nucleotide excision repair
Mihaela Robu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Repair of Double-Strand Breaks by End Joining
Kishore K. Chiruvella et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
Base Excision Repair
Hans E. Krokan et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
Defective DNA double-strand break repair in pediatric systemic lupus erythematosus
Robert C. Davies et al.
ARTHRITIS AND RHEUMATISM (2012)
Regulation of DNA cross-link repair by the Fanconi anemia/BRCA pathway
Hyungjin Kim et al.
GENES & DEVELOPMENT (2012)
PAMPs and DAMPs: signal 0s that spur autophagy and immunity
Daolin Tang et al.
IMMUNOLOGICAL REVIEWS (2012)
R Loops: From Transcription Byproducts to Threats to Genome Stability
Andres Aguilera et al.
MOLECULAR CELL (2012)
Poly(ADP-Ribosyl)ation of High Mobility Group Box 1 (HMGB1) Protein Enhances Inhibition of Efferocytosis
Kasey Davis et al.
MOLECULAR MEDICINE (2012)
The DNA damage response and cancer therapy
Christopher J. Lord et al.
NATURE (2012)
UV-sensitive syndrome protein UVSSA recruits USP7 to regulate transcription-coupled repair
Petra Schwertman et al.
NATURE GENETICS (2012)
Regulation of inflammasome signaling
Vijay A. K. Rathinam et al.
NATURE IMMUNOLOGY (2012)
Acetylation modulates cellular distribution and DNA sensing ability of interferon-inducible protein IFI16
Tuo Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Mammalian mismatch repair: error-free or error-prone?
Javier Pena-Diaz et al.
TRENDS IN BIOCHEMICAL SCIENCES (2012)
Nucleotide excision repair: new tricks with old bricks
Irene Kamileri et al.
TRENDS IN GENETICS (2012)
Signaling in Innate Immunity and Inflammation
Kim Newton et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2012)
DNA repair dysregulation from cancer driver to therapeutic target
Nicola J. Curtin
NATURE REVIEWS CANCER (2012)
Balancing repair and tolerance of DNA damage caused by alkylating agents
Dragony Fu et al.
NATURE REVIEWS CANCER (2012)
Genetic variation in the bioactivation pathway for polycyclic hydrocarbons and heterocyclic amines in relation to risk of colorectal neoplasia
Hansong Wang et al.
CARCINOGENESIS (2011)
Linking RNA Polymerase Backtracking to Genome Instability in E. coli
Dipak Dutta et al.
CELL (2011)
IFI16 Acts as a Nuclear Pathogen Sensor to Induce the Inflammasome in Response to Kaposi Sarcoma-Associated Herpesvirus Infection
Nagaraj Kerur et al.
CELL HOST & MICROBE (2011)
Innate Immune Recognition of an AT-Rich Stem-Loop DNA Motif in the Plasmodium falciparum Genome
Shruti Sharma et al.
IMMUNITY (2011)
The DNA Damage Response Induces IFN
Sabrina Brzostek-Racine et al.
JOURNAL OF IMMUNOLOGY (2011)
Adenovirus Membrane Penetration Activates the NLRP3 Inflammasome
A. U. Barlan et al.
JOURNAL OF VIROLOGY (2011)
Co-directional replication-transcription conflicts lead to replication restart
Houra Merrikh et al.
NATURE (2011)
The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells
Zhiqiang Zhang et al.
NATURE IMMUNOLOGY (2011)
Pattern Recognition Receptors and Inflammation
Osamu Takeuchi et al.
CELL (2010)
Immunity, Inflammation, and Cancer
Sergei I. Grivennikov et al.
CELL (2010)
Increased Foxp3+ Regulatory T Cells in Poly(ADP-Ribose) Polymerase-1 Deficiency
Francesca Nasta et al.
JOURNAL OF IMMUNOLOGY (2010)
Langerhans Cells Serve as Immunoregulatory Cells by Activating NKT Cells
Atsushi Fukunaga et al.
JOURNAL OF IMMUNOLOGY (2010)
A Review of Trabectedin (ET-743): A Unique Mechanism of Action
Maurizio D'Incalci et al.
MOLECULAR CANCER THERAPEUTICS (2010)
A Cytoplasmic ATM-TRAF6-cIAP1 Module Links Nuclear DNA Damage Signaling to Ubiquitin-Mediated NF-κB Activation
Michael Hinz et al.
MOLECULAR CELL (2010)
Microsatellite instability in colorectal cancer-the stable evidence
Eduardo Vilar et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2010)
NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production?
Jurg Tschopp et al.
NATURE REVIEWS IMMUNOLOGY (2010)
NanoGenotoxicology: The DNA damaging potential of engineered nanomaterials
Neenu Singh et al.
BIOMATERIALS (2009)
Cancer-related inflammation, the seventh hallmark of cancer: links to genetic instability
Francesco Colotta et al.
CARCINOGENESIS (2009)
RNA Polymerase III Detects Cytosolic DNA and Induces Type I Interferons through the RIG-I Pathway
Yu-Hsin Chiu et al.
CELL (2009)
Regulation of Interactions with Sliding Clamps During DNA Replication and Repair
Francisco J. Lopez de Saro
CURRENT GENOMICS (2009)
Identification of the ADP-Ribosylation Sites in the PARP-1 Automodification Domain: Analysis and Implications
Zhihua Tao et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2009)
A Genome-wide siRNA Screen Reveals Diverse Cellular Processes and Pathways that Mediate Genome Stability
Renee D. Paulsen et al.
MOLECULAR CELL (2009)
A Nuclear Poly(ADP-Ribose)-Dependent Signalosome Confers DNA Damage-Induced IκB Kinase Activation
Michael Stilmann et al.
MOLECULAR CELL (2009)
RIG-I-dependent sensing of poly(dA:dT) through the induction of an RNA polymerase III-transcribed RNA intermediate
Andrea Ablasser et al.
NATURE IMMUNOLOGY (2009)
Toll-like receptor 2 and poly(ADP-ribose) polymerase 1 promote central nervous system neuroinflammation in progressive EAE
Mauricio F. Farez et al.
NATURE IMMUNOLOGY (2009)
An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome
Tilmann Buerckstuemmer et al.
NATURE IMMUNOLOGY (2009)
Oxidative stress induces degradation of mitochondrial DNA
Inna Shokolenko et al.
NUCLEIC ACIDS RESEARCH (2009)
Activation of the aryl hydrocarbon receptor promotes allograft-specific tolerance through direct and dendritic cell-mediated effects on regulatory T cells
Ehud Hauben et al.
BLOOD (2008)
Transcriptional regulation by Poly(ADP-ribose) polymerase-1 during T cell activation
Luis Saenz et al.
BMC GENOMICS (2008)
Trex1 prevents cell-intrinsic initiation of autoimmunity
Daniel B. Stetson et al.
CELL (2008)
Do all of the neurologic diseases in patients with DNA repair gene mutations result from the accumulation of DNA damage?
P. J. Brooks et al.
DNA REPAIR (2008)
Cancer-related inflammation
Alberto Mantovani et al.
NATURE (2008)
Single-strand break repair and genetic disease
Keith W. Caldecott
NATURE REVIEWS GENETICS (2008)
Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
Catherine Dostert et al.
SCIENCE (2008)
Trex1 exonuclease degrades ssDNA to prevent chronic checkpoint activation and autoimmune disease
Yun-Gui Yang et al.
CELL (2007)
DAI (DLM-1/ZBP1) is a cytosolic DNA sensor and an activator of innate immune response
Akinori Takaoka et al.
NATURE (2007)
A key role for poly(ADP-Ribose) polymerase-1 activity during human dendritic cell maturation
Alessandra Aldinucci et al.
JOURNAL OF IMMUNOLOGY (2007)
ATP activates a reactive oxygen species-dependent oxidative stress response and secretion of proinflammatory cytokines in macrophages
Cristiane M. Cruz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Replication fork stalling at natural impediments
Ekaterina V. Mirkin et al.
MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2007)
A role for inflammatory mediators in the induction of immunoregulatory B cells
Yumi Matsumura et al.
JOURNAL OF IMMUNOLOGY (2006)
Chronic inflammation and oxidative stress in the genesis and perpetuation of cancer: role of lipid peroxidation, DNA damage, and repair
Helmut Bartsch et al.
LANGENBECKS ARCHIVES OF SURGERY (2006)
Mutations in the gene encoding the 3′-5′ DNA exonuclease TREX1 cause Aicardi-Goutieres syndrome at the AGS1 locus
Yanick J. Crow et al.
NATURE GENETICS (2006)
Direct phosphorylation and regulation of poly(ADP-ribose) polymerase-1 by extracellular signal-regulated kinases 1/2
TM Kauppinen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
The multifaceted mismatch-repair system
J Jiricny
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2006)
The DNA damage response arouses the immune system
S Gasser et al.
CANCER RESEARCH (2006)
Parp-1 protects homologous recombination from interference by Ku and ligase IV in vertebrate cells
H Hochegger et al.
EMBO JOURNAL (2006)
Pathogen recognition and innate immunity
S Akira et al.
CELL (2006)
Recognition of cytosolic DNA activates an IRF3-dependent innate immune response
DB Stetson et al.
IMMUNITY (2006)
Inflammation, gene mutation and photoimmunosuppression in response to UVR-induced oxidative damage contributes to photocarcinogenesis
GA Halliday
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2005)
Neutrophils infiltrating ultraviolet B-irradiated normal human skin display high IL-10 expression
G Piskin et al.
ARCHIVES OF DERMATOLOGICAL RESEARCH (2005)
Metals, toxicity and oxidative stress
M Valko et al.
CURRENT MEDICINAL CHEMISTRY (2005)
Timeline - Chemotherapy and the war on cancer
BA Chabner et al.
NATURE REVIEWS CANCER (2005)
Repairing DNA-methylation damage
B Sedgwick
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2004)
Vaccination with plasmid DNA activates dendritic cells via toll-like receptor 9 (TLR9) but functions in TLR9-deficient mice
B Spies et al.
JOURNAL OF IMMUNOLOGY (2003)
Release of chromatin protein HMGB1 by necrotic cells triggers inflammation
P Scaffidi et al.
NATURE (2002)
Ultraviolet B radiation induces a transient appearance of IL-4+ neutrophils, which support the development of Th2 responses
MBM Teunissen et al.
JOURNAL OF IMMUNOLOGY (2002)
Chronic intestinal inflammatory condition generates IL-10-producing regulatory B cell subset characterized by CD1d upregulation
A Mizoguchi et al.
IMMUNITY (2002)
A Toll-like receptor recognizes bacterial DNA
H Hemmi et al.
NATURE (2000)
Advances in immunology: Innate immunity.
R Medzhitov et al.
NEW ENGLAND JOURNAL OF MEDICINE (2000)