Candida albicansand candidalysin in inflammatory disorders and cancer

As our understanding of mycology progresses, the impact of fungal microbes on human health has become increasingly evident.Candida albicansis a common commensal fungus that gives rise to local and systemic infections, particularly in immunocompromised patients where it can result in mortality. However,C. albicanshas also been quietly linked with a variety of inflammatory disorders, to which it has traditionally been considered incidental; recent studies may now provide new aspects of these relationships for further consideration. This review provides a novel perspective on the impact ofC. albicansand its peptide toxin, candidalysin, on human health, exploring their contributions to pathology within a variety of diseases.

Automated summary

Advancements in mycology have highlighted the significant impact of fungal microbes on human health. Candida albicans, a common fungus, not only causes infections but is also associated with various inflammatory disorders, suggesting new avenues for research.