Related references
Note: Only part of the references are listed.Vitamin C promotes the proliferation and effector functions of human γδ T cells
Leonce Kouakanou et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2020)
Translating gammadelta (gamma delta) T cells and their receptors into cancer cell therapies
Zsolt Sebestyen et al.
NATURE REVIEWS DRUG DISCOVERY (2020)
Precursors for Nonlymphoid-Tissue Treg Cells Reside in Secondary Lymphoid Organs and Are Programmed by the Transcription Factor BATF
Michael Delacher et al.
IMMUNITY (2020)
The rapidly advancing Class 2 CRISPR-Cas technologies: A customizable toolbox for molecular manipulations
Jingyi Wang et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2020)
VEGF-C-driven lymphatic drainage enables immunosurveillance of brain tumours
Eric Song et al.
NATURE (2020)
γδ T cells and adipocyte IL-17RC control fat innervation and thermogenesis
Bo Hu et al.
NATURE (2020)
Butyrophilin 2A1 is essential for phosphoantigen reactivity by γδ T cells
Marc Rigau et al.
SCIENCE (2020)
Chemokines and their Receptors: Multifaceted Roles in Cancer Progression and Potential Value as Cancer Prognostic Markers
Ha Thi Thu Do et al.
CANCERS (2020)
Gene editing and CRISPR in the clinic: current and future perspectives
Matthew P. Hirakawa et al.
BIOSCIENCE REPORTS (2020)
Pooled Knockin Targeting for Genome Engineering of Cellular Immunotherapies
Theodore L. Roth et al.
CELL (2020)
Hypoxia regulates the differentiation and anti-tumor effector functions of γδT cells in oral cancer
S. K. Sureshbabu et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2020)
The Role of Antigen Spreading in the Efficacy of Immunotherapies
Peter Brossart
CLINICAL CANCER RESEARCH (2020)
Glypican-3-Specific CAR T Cells Coexpressing IL15 and IL21 Have Superior Expansion and Antitumor Activity against Hepatocellular Carcinoma
Sai Arun Batra et al.
CANCER IMMUNOLOGY RESEARCH (2020)
Butyrophilin-2A1 Directly Binds Germline-Encoded Regions of the Vγ9Vδ2 TCR and Is Essential for Phosphoantigen Sensing
Mohindar M. Karunakaran et al.
IMMUNITY (2020)
Single-Cell RNA Sequencing of Tumor-Infiltrating NK Cells Reveals that Inhibition of Transcription Factor HIF-1α Unleashes NK Cell Activity
Jing Ni et al.
IMMUNITY (2020)
CRISPR-Based Synthetic Transcription Factors In Vivo: The Future of Therapeutic Cellular Programming
Matthew Pandelakis et al.
CELL SYSTEMS (2020)
Gene modification strategies for next-generation CAR T cells against solid cancers
Yonggui Tian et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2020)
Combining Oncolytic Viruses With Cancer Immunotherapy: Establishing a New Generation of Cancer Treatment
Tao Shi et al.
FRONTIERS IN IMMUNOLOGY (2020)
γδ T Cells: The Ideal Tool for Cancer Immunotherapy
Mahboubeh Yazdanifar et al.
CELLS (2020)
Adoptive cellular therapy with T cells expressing the dendritic cell growth factor Flt3L drives epitope spreading and antitumor immunity
Junyun Lai et al.
NATURE IMMUNOLOGY (2020)
Cancer Cells Don't Live Alone: Metabolic Communication within Tumor Microenvironments
Fuming Li et al.
DEVELOPMENTAL CELL (2020)
An Oncogenic Alteration Creates a Microenvironment that Promotes Tumor Progression by Conferring a Metabolic Advantage to Regulatory T Cells
Shogo Kumagai et al.
IMMUNITY (2020)
Chimeric Antigen Receptor Designed to Prevent Ubiquitination and Downregulation Showed Durable Antitumor Efficacy
Wentao Li et al.
IMMUNITY (2020)
CAR-T Cells Hit the Tumor Microenvironment: Strategies to Overcome Tumor Escape
Alba Rodriguez-Garcia et al.
FRONTIERS IN IMMUNOLOGY (2020)
Gamma-Delta CAR-T Cells Show CAR-Directed and Independent Activity Against Leukemia
Meir Rozenbaum et al.
FRONTIERS IN IMMUNOLOGY (2020)
gamma 9 delta 2T cell diversity and the receptor interface with tumor cells
Anna Vyborova et al.
JOURNAL OF CLINICAL INVESTIGATION (2020)
Accumulation of long-chain fatty acids in the tumor microenvironment drives dysfunction in intrapancreatic CD8+ T cells
Teresa Manzo et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2020)
cDC1 prime and are licensed by CD4+T cells to induce anti-tumour immunity
Stephen T. Ferris et al.
NATURE (2020)
Inefficient CAR-proximal signaling blunts antigen sensitivity
Venugopal Gudipati et al.
NATURE IMMUNOLOGY (2020)
Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen
Santosha A. Vardhana et al.
NATURE IMMUNOLOGY (2020)
The safety and clinical effects of administering a multiantigen-targeted T cell therapy to patients with multiple myeloma
Premal D. Lulla et al.
SCIENCE TRANSLATIONAL MEDICINE (2020)
Turning Cold into Hot: Firing up the Tumor Microenvironment
Qianqian Duan et al.
TRENDS IN CANCER (2020)
Receptor signaling, transcriptional, and metabolic regulation of T cell exhaustion
Mumtaz Y. Balkhi
ONCOIMMUNOLOGY (2020)
CD40 Ligand-Modified Chimeric Antigen Receptor T Cells Enhance Antitumor Function by Eliciting an Endogenous Antitumor Response
Nicholas F. Kuhn et al.
CANCER CELL (2019)
Disruption of CTLA-4 expression on peripheral blood CD8+T cell enhances anti-tumor efficacy in bladder cancer
Wei Zhang et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2019)
Single-Cell Transcriptomics of Regulatory T Cells Reveals Trajectories of Tissue Adaptation
Ricardo J. Miragaia et al.
IMMUNITY (2019)
NR4A transcription factors limit CAR T cell function in solid tumours
Joyce Chen et al.
NATURE (2019)
One-step generation of modular CAR-T cells with AAV-Cpf1
Xiaoyun Dai et al.
NATURE METHODS (2019)
Allogenic V9V2 T cell as new potential immunotherapy drug for solid tumor: a case study for cholangiocarcinoma
Mohammed Alnaggar et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2019)
Cancer-cell-secreted CXCL11 promoted CD8+ T cells infiltration through docetaxel-induced-release of HMGB1 in NSCLC
Qun Gao et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2019)
CAR T-Cells Targeting the Integrin αvβ6 and Co-Expressing the Chemokine Receptor CXCR2 Demonstrate Enhanced Homing and Efficacy against Several Solid Malignancies
Lynsey M. Whilding et al.
CANCERS (2019)
Cooperation between Constitutive and Inducible Chemokines Enables T Cell Engraftment and Immune Attack in Solid Tumors
Denarda Dangaj et al.
CANCER CELL (2019)
Supercharging adoptive T cell therapy to overcome solid tumor-induced immunosuppression
Sherly Mardiana et al.
SCIENCE TRANSLATIONAL MEDICINE (2019)
Solid Tumors Challenges and New Insights of CAR T Cell Engineering
Safa Tahmasebi et al.
STEM CELL REVIEWS AND REPORTS (2019)
Chimeric antigen receptor T (CAR-T) cells expanded with IL-7/IL-15 mediate superior antitumor effects
Jianxia Zhou et al.
PROTEIN & CELL (2019)
Tertiary Lymphoid Organs in Cancer Immunology: Mechanisms and the New Strategy for Immunotherapy
Liangbin Lin et al.
FRONTIERS IN IMMUNOLOGY (2019)
Drug Inducible CRISPR/Cas Systems
Jingfang Zhang et al.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2019)
Improved survival of chimeric antigen receptor-engineered T (CAR-T) and tumor-specific T cells caused by anti-programmed cell death protein 1 single-chain variable fragment-producing CAR-T cells
Masao Nakajima et al.
CANCER SCIENCE (2019)
Systematic Immunotherapy Target Discovery Using Genome-Scale In Vivo CRISPR Screens in CD8 T Cells
Matthew B. Dong et al.
CELL (2019)
Multiplexed genome engineering by Cas12a and CRISPR arrays encoded on single transcripts
Carlo C. Campa et al.
NATURE METHODS (2019)
Tissue-Resident Memory T Cells in Cancer Immunosurveillance
Simone L. Park et al.
TRENDS IN IMMUNOLOGY (2019)
Dead Cas Systems: Types, Principles, and Applications
Sergey Brezgin et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Tumor-intrinsic signaling pathways: key roles in the regulation of the immunosuppressive tumor microenvironment
Li Yang et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2019)
Multi-antigen-targeted chimeric antigen receptor T cells for cancer therapy
Xiao Han et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2019)
Inhibitory receptors and ligands beyond PD-1, PD-L1 and CTLA-4: breakthroughs or backups
Lawrence P. Andrews et al.
NATURE IMMUNOLOGY (2019)
CRISPR-Cas9 disruption of PD-1 enhances activity of universal EGFRvIII CAR T cells in a preclinical model of human glioblastoma
Bryan D. Choi et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2019)
Eradication of Neuroblastoma by T Cells Redirected with an Optimized GD2-Specific Chimeric Antigen Receptor and Interleukin-15
Yuhui Chen et al.
CLINICAL CANCER RESEARCH (2019)
Cancer immunotherapy with lymphocytes genetically engineered with T cell receptors for solid cancers
Lei Chen et al.
IMMUNOLOGY LETTERS (2019)
Tissue-resident memory CD8+ T cells promote melanoma-immune equilibrium in skin
Simone L. Park et al.
NATURE (2019)
Tisagenlecleucel in Adult Relapsed or Refractory Diffuse Large B-Cell Lymphoma
Stephen J. Schuster et al.
NEW ENGLAND JOURNAL OF MEDICINE (2019)
c-Jun overexpression in CAR T cells induces exhaustion resistance
Rachel C. Lynn et al.
NATURE (2019)
Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy
Jun Wei et al.
NATURE (2019)
Boosting γδ T cell-mediated antibody-dependent cellular cytotoxicity by PD-1 blockade in follicular lymphoma
Cedric Rossi et al.
ONCOIMMUNOLOGY (2019)
PD-1 signaling modulates interferon-γ production by Gamma Delta (γδ) T-Cells in response to leukemia
Timm Hoeres et al.
ONCOIMMUNOLOGY (2019)
γδ T cells: pleiotropic immune effectors with therapeutic potential in cancer
Bruno Silva-Santos et al.
NATURE REVIEWS CANCER (2019)
Cold Tumors: A Therapeutic Challenge for Immunotherapy
Paola Bonaventura et al.
FRONTIERS IN IMMUNOLOGY (2019)
CAR T Cells for Solid Tumors: New Strategies for Finding, Infiltrating, and Surviving in the Tumor Microenvironment
Marina Martinez et al.
FRONTIERS IN IMMUNOLOGY (2019)
Trivalent CAR T cells overcome interpatient antigenic variability in glioblastoma
Kevin Bielamowicz et al.
NEURO-ONCOLOGY (2018)
The Common Cytokine Receptor. Chain Family of Cytokines
Jian-Xin Lin et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2018)
Cytokines in Cancer Immunotherapy
Thomas A. Waldmann
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2018)
High-Affinity GD2-Specific CAR T Cells Induce Fatal Encephalitis in a Preclinical Neuroblastoma Model
Sarah A. Richman et al.
CANCER IMMUNOLOGY RESEARCH (2018)
Regulatory functions of gamma delta T cells
Christian Peters et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2018)
Adoptive Transfer of Interleukin-21-stimulated Human CD8+ T Memory Stem Cells Efficiently Inhibits Tumor Growth
Yingshi Chen et al.
JOURNAL OF IMMUNOTHERAPY (2018)
IL-7 and CCL19 expression in CAR-T cells improves immune cell infiltration and CAR-T cell survival in the tumor
Keishi Adachi et al.
NATURE BIOTECHNOLOGY (2018)
Understanding the tumor immune microenvironment (TIME) for effective therapy
Mikhail Binnewies et al.
NATURE MEDICINE (2018)
A novel chimeric antigen receptor containing a JAK-STAT signaling domain mediates superior antitumor effects
Yuki Kagoya et al.
NATURE MEDICINE (2018)
Long-Term Follow-up of CD19 CAR Therapy in Acute Lymphoblastic Leukemia
Jae H. Park et al.
NEW ENGLAND JOURNAL OF MEDICINE (2018)
CAR T cell immunotherapy for human cancer
Carl H. June et al.
SCIENCE (2018)
Enhancing the Potency and Specificity of Engineered T Cells for Cancer Treatment
Sujita Sukumaran et al.
CANCER DISCOVERY (2018)
Engineered Tumor-Targeted T Cells Mediate Enhanced Anti-Tumor Efficacy Both Directly and through Activation of the Endogenous Immune System
Mauro P. Avanzi et al.
CELL REPORTS (2018)
Improving the Efficiency of Vγ9Vδ2 T Cell Immunotherapy in Cancer
Timm Hoeres et al.
FRONTIERS IN IMMUNOLOGY (2018)
Towards Deciphering the Hidden Mechanisms That Contribute to the Antigenic Activation Process of Human Vγ9Vδ2 T Cells
Lola Boutin et al.
FRONTIERS IN IMMUNOLOGY (2018)
GMP-Grade Manufacturing of T Cells Engineered to Express a Defined γδTCR
Trudy Straetemans et al.
FRONTIERS IN IMMUNOLOGY (2018)
Intra-tumoral delivery of CXCL11 via a vaccinia virus, but not by modified T cells, enhances the efficacy of adoptive T cell therapy and vaccines
Edmund K. Moon et al.
ONCOIMMUNOLOGY (2018)
Reprogramming human T cell function and specificity with non-viral genome targeting
Theodore L. Roth et al.
NATURE (2018)
Disruption of TET2 promotes the therapeutic efficacy of CD19-targeted T cells
Joseph A. Fraietta et al.
NATURE (2018)
Targeted delivery of a PD-1-blocking scFv by CAR-T cells enhances anti-tumor efficacy in vivo
Sarwish Rafiq et al.
NATURE BIOTECHNOLOGY (2018)
Tumor Antigen Escape from CAR T-cell Therapy
Robbie G. Majzner et al.
CANCER DISCOVERY (2018)
PD1-CD28 Fusion Protein Enables CD4+T Cell Help for Adoptive T Cell Therapy in Models of Pancreatic Cancer and Non-hodgkin Lymphoma
Felicitas Rataj et al.
FRONTIERS IN IMMUNOLOGY (2018)
Emerging Cellular Therapies for Cancer
Sonia Guedan et al.
Annual Review of Immunology (2018)
Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function
Eric Shifrut et al.
CELL (2018)
Universal CARs, universal T cells, and universal CAR T cells
Juanjuan Zhao et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2018)
Industrializing Autologous Adoptive Immunotherapies: Manufacturing Advances and Challenges
Rohin K. Iyer et al.
FRONTIERS IN MEDICINE (2018)
Targeting the adenosine 2A receptor enhances chimeric antigen receptor T cell efficacy
Paul A. Beavis et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
Cocktail treatment with EGFR-specific and CD133-specific chimeric antigen receptor-modified T cells in a patient with advanced cholangiocarcinoma
Kai-chao Feng et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2017)
Tumor Antigen and Receptor Densities Regulate Efficacy of a Chimeric Antigen Receptor Targeting Anaplastic Lymphoma Kinase
Alec J. Walker et al.
MOLECULAR THERAPY (2017)
Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection
Justin Eyquem et al.
NATURE (2017)
Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism
Youdong Pan et al.
NATURE (2017)
Runx3 programs CD8+ T cell residency in non-lymphoid tissues and tumours
J. Justin Milner et al.
NATURE (2017)
Chimeric Antigen Receptor T Cells in Refractory B-Cell Lymphomas
Stephen J. Schuster et al.
NEW ENGLAND JOURNAL OF MEDICINE (2017)
Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma
S. S. Neelapu et al.
NEW ENGLAND JOURNAL OF MEDICINE (2017)
A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma
Donald M. O'Rourke et al.
SCIENCE TRANSLATIONAL MEDICINE (2017)
The Ambiguous Role of γδ T Lymphocytes in Antitumor Immunity
Guranda Chitadze et al.
TRENDS IN IMMUNOLOGY (2017)
Constitutive Signaling from an Engineered IL7 Receptor Promotes Durable Tumor Elimination by Tumor-Redirected T Cells
Thomas Shum et al.
CANCER DISCOVERY (2017)
A versatile system for rapid multiplex genome-edited CAR T cell generation
Jiangtao Ren et al.
ONCOTARGET (2017)
CAR T Cells Releasing IL-18 Convert to T-Bethigh FoxO1low Effectors that Exhibit Augmented Activity against Advanced Solid Tumors
Markus Chmielewski et al.
CELL REPORTS (2017)
Augmentation of Antitumor Immunity by Human and Mouse CAR T Cells Secreting IL-18
Biliang Hu et al.
CELL REPORTS (2017)
Safety and Efficacy of Intratumoral Injections of Chimeric Antigen Receptor (CAR) T Cells in Metastatic Breast Cancer
Julia Tchou et al.
CANCER IMMUNOLOGY RESEARCH (2017)
Transgenic Expression of IL15 Improves Antiglioma Activity of IL13Rα2-CAR T Cells but Results in Antigen Loss Variants
Giedre Krenciute et al.
CANCER IMMUNOLOGY RESEARCH (2017)
CRISPR-Cas9 mediated LAG-3 disruption in CAR-T cells
Yongping Zhang et al.
FRONTIERS OF MEDICINE (2017)
CAR T-cell intrinsic PD-1 checkpoint blockade: A two-in-one approach for solid tumor immunotherapy
Nan Chen et al.
ONCOIMMUNOLOGY (2017)
A TCR-based Chimeric Antigen Receptor
Even Waiseng et al.
SCIENTIFIC REPORTS (2017)
Systematic analysis of early phase clinical studies for patients with breast cancer: Inclusion of patients with brain metastasis
R. Costa et al.
CANCER TREATMENT REVIEWS (2017)
Acquisition of a CD19-negative myeloid phenotype allows immune escape of MLL-rearranged B-ALL from CD19 CAR-T-cell therapy
Rebecca Gardner et al.
BLOOD (2016)
Cancer immunotherapy: the beginning of the end of cancer?
Sofia Farkona et al.
BMC MEDICINE (2016)
A Chimeric Switch-Receptor Targeting PD1 Augments the Efficacy of Second-Generation CAR T Cells in Advanced Solid Tumors
Xiaojun Liu et al.
CANCER RESEARCH (2016)
Cancer Immunosurveillance by Tissue-Resident Innate Lymphoid Cells and Innate-like T Cells
Saida Dadi et al.
CELL (2016)
Precision Tumor Recognition by T Cells With Combinatorial Antigen-Sensing Circuits
Kole T. Roybal et al.
CELL (2016)
Tumor-Specific T Cell Dysfunction Is a Dynamic Antigen-Driven Differentiation Program Initiated Early during Tumorigenesis
Andrea Schietinger et al.
IMMUNITY (2016)
Human CAR T cells with cell-intrinsic PD-1 checkpoint blockade resist tumor-mediated inhibition
Leonid Cherkassky et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
BET bromodomain inhibition enhances T cell persistence and function in adoptive immunotherapy models
Yuki Kagoya et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
Driving an improved CAR for cancer immunotherapy
Xiaopei Huang et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
High Efficiency CRISPR/Cas9-mediated Gene Editing in Primary Human T-cells Using Mutant Adenoviral E4orf6/E1b55k Helper Proteins
Kamila S. Gwiazda et al.
MOLECULAR THERAPY (2016)
Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy
Christine E. Brown et al.
NEW ENGLAND JOURNAL OF MEDICINE (2016)
Human Vδ2 T cells are a major source of interleukin-9
Christian Peters et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Hobit and Blimp1 instruct a universal transcriptional program of tissue residency in lymphocytes
Laura K. Mackay et al.
SCIENCE (2016)
Stereotaxic administrations of allogeneic human Vγ9Vδ2 T cells efficiently control the development of human glioblastoma brain tumors
Ulrich Jarry et al.
ONCOIMMUNOLOGY (2016)
CRISPR-Cas9 mediated efficient PD-1 disruption on human primary T cells from cancer patients
Shu Su et al.
SCIENTIFIC REPORTS (2016)
Toxicities of the anti-PD-1 and anti-PD-L1 immune checkpoint antibodies
J. Naidoo et al.
ANNALS OF ONCOLOGY (2015)
Tumor indoleamine 2,3-dioxygenase (IDO) inhibits CD19-CAR T cells and is downregulated by lymphodepleting drugs
Soranobu Ninomiya et al.
BLOOD (2015)
Engineering Complex Synthetic Transcriptional Programs with CRISPR RNA Scaffolds
Jesse G. Zalatan et al.
CELL (2015)
Different cytokine and stimulation conditions influence the expansion and immune phenotype of third-generation chimeric antigen receptor T cells specific for tumor antigen GD2
Tessa Gargett et al.
CYTOTHERAPY (2015)
Human Epidermal Growth Factor Receptor 2 (HER2) -Specific Chimeric Antigen Receptor-Modified T Cells for the Immunotherapy of HER2-Positive Sarcoma
Nabil Ahmed et al.
JOURNAL OF CLINICAL ONCOLOGY (2015)
Impact of a New Fusion Receptor on PD-1-Mediated Immunosuppression in Adoptive T Cell Therapy
Sebastian Kobold et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2015)
Enhancing Antitumor Efficacy of Chimeric Antigen Receptor T Cells Through Constitutive CD40L Expression
Kevin J. Curran et al.
MOLECULAR THERAPY (2015)
Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T lymphocytes
Ignazio Caruana et al.
NATURE MEDICINE (2015)
4-1BB costimulation ameliorates T cell exhaustion induced by tonic signaling of chimeric antigen receptors
Adrienne H. Long et al.
NATURE MEDICINE (2015)
Overcoming Antigen Escape with CAR T-cell Therapy
Hollie J. Jackson et al.
CANCER DISCOVERY (2015)
Impact of a New Fusion Receptor on PD-1-Mediated Immunosuppression in Adoptive T Cell Therapy
Sebastian Kobold et al.
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2015)
CAR-T Cells Inflict Sequential Killing of Multiple Tumor Target Cells
Alexander J. Davenport et al.
CANCER IMMUNOLOGY RESEARCH (2015)
IL-12 secreting tumor-targeted chimeric antigen receptor T cells eradicate ovarian tumors in vivo
Mythili Koneru et al.
ONCOIMMUNOLOGY (2015)
Empowering gamma delta T cells with antitumor immunity by dendritic cell-based immunotherapy
Heleen H. Van Acker et al.
ONCOIMMUNOLOGY (2015)
Anergic bone marrow Vγ9Vδ2 T cells as early and long-lasting markers of PD-1-targetable microenvironment-induced immune suppression in human myeloma
Barbara Castella et al.
ONCOIMMUNOLOGY (2015)
γδ T Cells: First Line of Defense and Beyond
Yueh-hsiu Chien et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 32 (2014)
Closely related T-memory stem cells correlate with in vivo expansion of CAR.CD19-T cells and are preserved by IL-7 and IL-15
Yang Xu et al.
BLOOD (2014)
Phenotype and regulation of immunosuppressive Vδ2-expressing γδ T cells
Christian Peters et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2014)
γδT17 Cells Promote the Accumulation and Expansion of Myeloid-Derived Suppressor Cells in Human Colorectal Cancer
Pin Wu et al.
IMMUNITY (2014)
Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia
Shannon L. Maude et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Regional delivery of mesothelin-targeted CAR T cell therapy generates potent and long-lasting CD4-dependent tumor immunity
Prasad S. Adusumilli et al.
SCIENCE TRANSLATIONAL MEDICINE (2014)
Targeting Fibroblast Activation Protein in Tumor Stroma with Chimeric Antigen Receptor T Cells Can Inhibit Tumor Growth and Augment Host Immunity without Severe Toxicity
Liang-Chuan S. Wang et al.
CANCER IMMUNOLOGY RESEARCH (2014)
Improving the safety of cell therapy products by suicide gene transfer
Benjamin S. Jones et al.
Frontiers in Pharmacology (2014)
IL-7 and IL-15 instruct the generation of human memory stem T cells from naive precursors
Nicoletta Cieri et al.
BLOOD (2013)
Repurposing CRISPR as an RNA-Guided Platform for Sequence-Specific Control of Gene Expression
Lei S. Qi et al.
CELL (2013)
CRISPR-Mediated Modular RNA-Guided Regulation of Transcription in Eukaryotes
Luke A. Gilbert et al.
CELL (2013)
What lessons can be learned from γδ T cell-based cancer immunotherapy trials?
Jean-Jacques Fournie et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2013)
Oncology Meets Immunology: The Cancer-Immunity Cycle
Daniel S. Chen et al.
IMMUNITY (2013)
Immune targeting of fibroblast activation protein triggers recognition of multipotent bone marrow stromal cells and cachexia
Eric Tran et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2013)
Repeated Systemic Administrations of Both Aminobisphosphonates and Human Vγ9Vδ2 T Cells Efficiently Control Tumor Development In Vivo
Thibault Santolaria et al.
JOURNAL OF IMMUNOLOGY (2013)
Bispecific T-cells Expressing Polyclonal Repertoire of Endogenous γδ T-cell Receptors and Introduced CD19-specific Chimeric Antigen Receptor
Drew C. Deniger et al.
MOLECULAR THERAPY (2013)
Generation of tumor-targeted human T lymphocytes from induced pluripotent stem cells for cancer therapy
Maria Themeli et al.
NATURE BIOTECHNOLOGY (2013)
Chimeric Antigen Receptor T Cells with Dissociated Signaling Domains Exhibit Focused Antitumor Activity with Reduced Potential for Toxicity In Vivo
Evripidis Lanitis et al.
CANCER IMMUNOLOGY RESEARCH (2013)
Six-of-the-best: unique contributions of γδ T cells to immunology
Pierre Vantourout et al.
NATURE REVIEWS IMMUNOLOGY (2013)
Tumor-targeted T cells modified to secrete IL-12 eradicate systemic tumors without need for prior conditioning
Hollie J. Pegram et al.
BLOOD (2012)
Key implication of CD277/butyrophilin-3 (BTN3A) in cellular stress sensing by a major human γδ T-cell subset
Christelle Harly et al.
BLOOD (2012)
Local Delivery of Interleukin-12 Using T Cells Targeting VEGF Receptor-2 Eradicates Multiple Vascularized Tumors in Mice
Dhanalakshmi Chinnasamy et al.
CLINICAL CANCER RESEARCH (2012)
IL-21 enhances the potential of human γδ T cells to provide B-cell help
Raj R. Bansal et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2012)
Dual Targeting of ErbB2 and MUC1 in Breast Cancer Using Chimeric Antigen Receptors Engineered to Provide Complementary Signaling
Scott Wilkie et al.
JOURNAL OF CLINICAL IMMUNOLOGY (2012)
Paths to stemness: building the ultimate antitumour T cell
Luca Gattinoni et al.
NATURE REVIEWS CANCER (2012)
Differentiation, phenotype, and function of interleukin-17-producing human Vγ9Vδ2 T cells
Nadia Caccamo et al.
BLOOD (2011)
Pilot trial of interleukin-2 and zoledronic acid to augment γδ T cells as treatment for patients with refractory renal cell carcinoma
Joshua M. Lang et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2011)
Antigen Spreading Contributes to MAGE Vaccination-Induced Regression of Melanoma Metastases
Veronique Corbiere et al.
CANCER RESEARCH (2011)
Hallmarks of Cancer: The Next Generation
Douglas Hanahan et al.
CELL (2011)
How tumors might withstand γδ T-cell attack
Aude-Helene Capietto et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2011)
Expression of a Functional CCR2 Receptor Enhances Tumor Localization and Tumor Eradication by Retargeted Human T cells Expressing a Mesothelin-Specific Chimeric Antibody Receptor
Edmund K. Moon et al.
CLINICAL CANCER RESEARCH (2011)
Expression and function of PD-1 in human γδ T cells that recognize phosphoantigens
Masashi Iwasaki et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2011)
Contribution of IL-17-producing γδ T cells to the efficacy of anticancer chemotherapy
Yuting Ma et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Chimeric Antigen Receptor-Modified T Cells in Chronic Lymphoid Leukemia
David L. Porter et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Phase I study of bromohydrin pyrophosphate (BrHPP, IPH 1101), a Vγ9Vδ2 T lymphocyte agonist in patients with solid tumors
Jaafar Bennouna et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2010)
In vivo manipulation of Vγ9Vδ2 T cells with zoledronate and low-dose interleukin-2 for immunotherapy of advanced breast cancer patients
S. Meraviglia et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2010)
Gene therapy using genetically modified lymphocytes targeting VEGFR-2 inhibits the growth of vascularized syngenic tumors in mice
Dhanalakshmi Chinnasamy et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Cytokine Requirements for the Differentiation and Expansion of IL-17A-and IL-22-Producing Human Vγ2Vδ2 T Cells
Kristin J. Ness-Schwickerath et al.
JOURNAL OF IMMUNOLOGY (2010)
Enhanced Tumor Trafficking of GD2 Chimeric Antigen Receptor T Cells by Expression of the Chemokine Receptor CCR2b
John A. Craddock et al.
JOURNAL OF IMMUNOTHERAPY (2010)
Case Report of a Serious Adverse Event Following the Administration of T Cells Transduced With a Chimeric Antigen Receptor Recognizing ERBB2
Richard A. Morgan et al.
MOLECULAR THERAPY (2010)
Preferential Th1 Cytokine Profile of Phosphoantigen-Stimulated Human V gamma 9V delta 2T Cells
Margaret R. Dunne et al.
MEDIATORS OF INFLAMMATION (2010)
Inhibition of phosphoantigen-mediated γδ T-cell proliferation by CD4+ CD25+ FoxP3+ regulatory T cells
Volker Kunzmann et al.
IMMUNOLOGY (2009)
Pitfalls on the roadmap to γδ T cell-based cancer immunotherapies
Ludovic Martinet et al.
IMMUNOLOGY LETTERS (2009)
IL-21-Mediated Potentiation of Antitumor Cytolytic and Proinflammatory Responses of Human Vγ9Vδ2 T Cells for Adoptive Immunotherapy
Aurelie Thedrez et al.
JOURNAL OF IMMUNOLOGY (2009)
Hypoxia increases tumor cell shedding of MHC class I chain-related molecule: Role of nitric oxide
D. Robert Siemens et al.
CANCER RESEARCH (2008)
Targeting human γδ T cells with zoledronate and interleukin-2 for immunotherapy of hormone-refractory prostate cancer
Francesco Dieli et al.
CANCER RESEARCH (2007)
Safety profile and anti-tumor effects of adoptive immunotherapy using gamma-delta T cells against advanced renal cell carcinoma: a pilot study
Hirohito Kobayashi et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2007)
CRISPR provides acquired resistance against viruses in prokaryotes
Rodolphe Barrangou et al.
SCIENCE (2007)
CXCR5 identifies a subset of Vγ9Vδ2 T cells which secrete IL-4 and IL-10 and help B cells for antibody production
Nadia Caccamo et al.
JOURNAL OF IMMUNOLOGY (2006)
Potentiation of antigen-stimulated Vγ9Vδ2 T cell cytokine production by immature dendritic cells (DC) and recpirocal effect on DC maturation
MC Devilder et al.
JOURNAL OF IMMUNOLOGY (2006)
In vivo immunomanipulation of Vγ9Vδ2 T cells with a synthetic phosphoantigen in a preclinical nonhuman primate model
H Sicard et al.
JOURNAL OF IMMUNOLOGY (2005)
Vγ9Vδ2 T cell response to colon carcinoma cells
M Corvaisier et al.
JOURNAL OF IMMUNOLOGY (2005)
Professional antigen-presentation function by human γδ T cells
M Brandes et al.
SCIENCE (2005)
Sensing cell stress and transformation through Vγ9Vδ2 T cell-mediated recognition of the isoprenoid pathway metabolites
M Bonneville et al.
MICROBES AND INFECTION (2005)
Reciprocal activating interaction between dendritic cells and pamidronate-stimulated gamma delta T cells: role of CD86 and inflammatory cytokines
L Conti et al.
JOURNAL OF IMMUNOLOGY (2005)
IL-15 enhances the in vivo antitumor activity of tumor-reactive CD8+ T Cells
CA Klebanoff et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Human γδ T cells as mediators of chimaeric-receptor redirected anti-tumour immunity
M Rischer et al.
BRITISH JOURNAL OF HAEMATOLOGY (2004)
The distinct contributions of murine T cell receptor (TCR)γδ+ and TCRαβ+ T cells to different stages of chemically induced skin cancer
M Girardi et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Human T cell receptor γδ cells recognize endogenous mevalonate metabolites in tumor cells
HJ Gober et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2003)
Tumour-derived soluble MIC ligands impair expression of NKG2D and T-cell activation
V Groh et al.
NATURE (2002)
Differentiation of human γδ T cells towards distinct memory phenotypes
M Eberl et al.
CELLULAR IMMUNOLOGY (2002)
Differentiation of resting human peripheral blood γδ T cells toward Th1-or Th2-phenotype
D Wesch et al.
CELLULAR IMMUNOLOGY (2001)
Share Paper
