Journal
IMMUNOLOGICAL INVESTIGATIONS
Volume 51, Issue 2, Pages 246-265Publisher
TAYLOR & FRANCIS INC
DOI: 10.1080/08820139.2020.1825480
Keywords
Coronavirus; 2019 novel coronavirus; COVID-19; host immune response; vaccine development
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The outbreak of COVID-19 poses a serious threat to public health and there is an urgent need for discovery methods for prevention and treatment. Understanding immunogenicity and immune responses may provide further information about the virus and aid in designing vaccines and novel therapies in the near future.
The outbreak of coronavirus disease 2019 (COVID-19) has posed a serious threat to public health. There is an urgent need for discovery methods for the prevention and treatment of COVID-19 infection. Understanding immunogenicity together with immune responses are expected to provide further information about this virus. We hope that this narrative review article may create new insights for researchers to take great strides toward designing vaccines and novel therapies in the near future. The functional properties of the immune system in COVID-19 infection is not exactly clarified yet. This is compounded by the many gaps in our understanding of the SARS-CoV-2 immunogenicity properties. Possible immune responses according to current literature are discussed as thefirst line of defenseand acquired immunity. Here, we focus on proposed modern preventive immunotherapy methods in COVID-19 infection.
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