Related references
Note: Only part of the references are listed.Physiological functions of FBW7 in cancer and metabolism
Kouhei Shimizu et al.
CELLULAR SIGNALLING (2018)
Next-generation proteasome inhibitors for cancer therapy
Ji Eun Park et al.
TRANSLATIONAL RESEARCH (2018)
NOTCH2 Hajdu-Cheney Mutations Escape SCFFBW7-Dependent Proteolysis to Promote Osteoporosis
Hidefumi Fukushima et al.
MOLECULAR CELL (2017)
The SCFβ-TRCP E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis
Kouhei Shimizu et al.
SCIENCE SIGNALING (2017)
The SCFβ-TRCP E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis
Kouhei Shimizu et al.
SCIENCE SIGNALING (2017)
Drugging the undruggables: exploring the ubiquitin system for drug development
Xiaodong Huang et al.
CELL RESEARCH (2016)
Sp7/Osterix Is Restricted to Bone-Forming Vertebrates where It Acts as a Dlx Co-factor in Osteoblast Specification
Hironori Hojo et al.
DEVELOPMENTAL CELL (2016)
p38 MAPK Signaling in Osteoblast Differentiation
Eddie Rodriguez-Carballo et al.
FRONTIERS IN CELL AND DEVELOPMENTAL BIOLOGY (2016)
Cbl-b and c-Cbl negatively regulate osteoblast differentiation by enhancing ubiquitination and degradation of Osterix
You Hee Choi et al.
BONE (2015)
Identification of C-terminal Hsp70-interacting protein as a mediator of tumour necrosis factor action in osteoblastdifferentiation by targeting osterix for degradation
Jianmin Xie et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2015)
Focus on the p38 MAPK signaling pathway in bone development and maintenance
Cyril Thouverey et al.
BONEKEY REPORTS (2015)
Tumor Suppression by the Fbw7 Ubiquitin Ligase: Mechanisms and Opportunities
Ryan J. Davis et al.
CANCER CELL (2014)
Preclinical Activity of the Oral Proteasome Inhibitor MLN9708 in Myeloma Bone Disease
Antonio Garcia-Gomez et al.
CLINICAL CANCER RESEARCH (2014)
Mitogen-activated Protein Kinase (MAPK)-regulated Interactions between Osterix and Runx2 Are Critical for the Transcriptional Osteogenic Program
Natalia Artigas et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Fbw7 Targets GATA3 through Cyclin-Dependent Kinase 2-Dependent Proteolysis and Contributes to Regulation of T-Cell Development
Kyoko Kitagawa et al.
MOLECULAR AND CELLULAR BIOLOGY (2014)
SGK3 Mediates INPP4B-Dependent PI3K Signaling in Breast Cancer
Jessica A. Gasser et al.
MOLECULAR CELL (2014)
Novel SCRG1/BST1 axis regulates self-renewal, migration, and osteogenic differentiation potential in mesenchymal stem cells
Emiko Aomatsu et al.
SCIENTIFIC REPORTS (2014)
F-box and WD Repeat Domain-containing-7 (Fbxw7) Protein Targets Endoplasmic Reticulum-anchored Osteogenic and Chondrogenic Transcriptional Factors for Degradation
Kanae Yumimoto et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
Genetic and molecular control of osterix in skeletal formation
Krishna M. Sinha et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2013)
The epoxyketone-based proteasome inhibitors carfilzomib and orally bioavailable oprozomib have anti-resorptive and bone-anabolic activity in addition to anti-myeloma effects
M. A. Hurchla et al.
LEUKEMIA (2013)
Characterization of Osterix Protein Stability and Physiological Role in Osteoblast Differentiation
Yanyan Peng et al.
PLOS ONE (2013)
The Ubiquitin Code
David Komander et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 81 (2012)
Interactions between extracellular signal-regulated kinase 1/2 and P38 Map kinase pathways in the control of RUNX2 phosphorylation and transcriptional activity
Chunxi Ge et al.
JOURNAL OF BONE AND MINERAL RESEARCH (2012)
mTOR Drives Its Own Activation via SCFβTrCP-Dependent Degradation of the mTOR Inhibitor DEPTOR
Daming Gao et al.
MOLECULAR CELL (2011)
SCFFBW7 regulates cellular apoptosis by targeting MCL1 for ubiquitylation and destruction
Hiroyuki Inuzuka et al.
NATURE (2011)
Phosphorylation by Casein Kinase I Promotes the Turnover of the Mdm2 Oncoprotein via the SCFβ-TRCP Ubiquitin Ligase
Hiroyuki Inuzuka et al.
CANCER CELL (2010)
The multiple levels of regulation by p53 ubiquitination
J. T. Lee et al.
CELL DEATH AND DIFFERENTIATION (2010)
p38 Regulates Expression of Osteoblast-specific Genes by Phosphorylation of Osterix
Maria Jose Ortuno et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
The p38 MAPK pathway is essential for skeletogenesis and bone homeostasis in mice
Matthew B. Greenblatt et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
The proteasome inhibitor, bortezomib suppresses primary myeloma and stimulates bone formation in myelomatous and nonmyelomatous bones in vivo
Angela Pennisi et al.
AMERICAN JOURNAL OF HEMATOLOGY (2009)
RING Domain E3 Ubiquitin Ligases
Raymond J. Deshaies et al.
ANNUAL REVIEW OF BIOCHEMISTRY (2009)
Genetic Control of Bone Formation
Gerard Karsenty et al.
ANNUAL REVIEW OF CELL AND DEVELOPMENTAL BIOLOGY (2009)
An inhibitor of NEDD8-activating enzyme as a new approach to treat cancer
Teresa A. Soucy et al.
NATURE (2009)
BMP-2 induces osterix expression through up-regulation of Dlx5 and its phosphorylation by p38
Arnau Ulsamer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Stimulation of new bone formation by the proteasome inhibitor, bortezomib:: implications for myeloma bone disease
Babatunde O. Oyajobi et al.
BRITISH JOURNAL OF HAEMATOLOGY (2007)
FBW7 mutations in leukemic cells mediate NOTCH pathway activation and resistance to γ-secretase inhibitors
Jennifer O'Neil et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
The proteasome inhibitor bortezomib affects osteoblast differentiation in vitro and in vivo in multiple myeloma patients
Nicola Giuliani et al.
BLOOD (2007)
Chromosomally unstable mouse tumours have genomic alterations similar to diverse human cancers
Richard S. Maser et al.
NATURE (2007)
NFAT and Osterix cooperatively regulate bone formation
T Koga et al.
NATURE MEDICINE (2005)
Immortalization of human fetal cells:: The life span of umbilical cord blood-derived cells can be prolonged without manipulating p16INK4a/RB braking pathway
M Terai et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
Inactivation of hCDC4 can cause chromosomal instability
H Rajagopalan et al.
NATURE (2004)
The novel zinc finger-containing transcription factor Osterix is required for osteoblast differentiation and bone formation
K Nakashima et al.
CELL (2002)