4.6 Article

Changes in intraocular pressure control in the first year after secondary intraocular lens implantation in children

Journal

EYE
Volume 35, Issue 7, Pages 2024-2029

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SPRINGERNATURE
DOI: 10.1038/s41433-020-01193-3

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Funding

  1. South Carolina Clinical & Translational Research Institute, Medical University of South Carolina's CTSA, NIH/NCATS [1UL1TR001450]

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The study aimed to compare intraocular pressure (IOP) control before and after secondary intraocular lens (IOL) implantation in children, finding that eyes with a history of traumatic cataract surgery and very young age at initial cataract surgery may have an increased risk of failure in postoperative IOP control.
Purpose To compare intraocular pressure (IOP) control before and during the first year after secondary intraocular lens (IOL) implantation in children. Methods This was a retrospective chart review of children who received secondary IOL implantation. We analyzed IOP and antiglaucoma medications before and after implantation. The latest exam with IOP measurement found within the 2-15 month period after IOL implantation was used for the postoperative data. Failure to maintain IOP control was defined as either the addition of antiglaucoma medication(s) or a rise in IOP > 4 mm Hg. Statistical analyses were performed to assess risk factors for failure to control IOP after surgery, namely age at IOL implantation, preoperative glaucoma status, and IOL fixation location. Results A total of 100 eyes were included. The mean duration of follow-up was 7.74 months (SD = 3.11). Twenty-three of one hundred eyes failed to maintain IOP control according to our definition. Eyes with a history of having had a traumatic cataract (n = 3) had a more than threefold increased risk of failure (P = 0.015). Although not statistically significant, very young age at initial cataract surgery (<2 months old) had a twofold increased risk of failure compared to an older age (>12 months old) (P = 0.213). No other risk factors were found to have statistical significance. Conclusion Secondary IOL implantation carries a modest risk of worsening IOP control in the first year after implantation, for which, a history of ocular trauma or young age at initial cataract surgery seems to present the highest risk.

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