Journal
EUROPEAN JOURNAL OF INTERNAL MEDICINE
Volume 82, Issue -, Pages 105-111Publisher
ELSEVIER
DOI: 10.1016/j.ejim.2020.09.024
Keywords
Atrial fibrillation; Screening; Integrated care; Smart technology
Categories
Funding
- National Natural Science Foundation of China [8147413]
- National Key Research and Development Project of China [2018YFC2001200]
- Health and Family Planning Commission of Heilongjiang Province, China [2017-036]
- NIHR Global Health Research Group on Atrial Fibrillation management at the University of Birmingham, UK
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Background. In the mobile Atrial Fibrillation App (mAFA)-II trial, the use of mobile health (mHealth) technology, incorporating AF screening and integrated management strategy, was associated with improved short-term clinical outcomes. The aim of this study was to report adherence/persistence and long term (>= 1 year) clinical outcomes of the mAFA-II trial, with mHealth-supported optimised stroke prevention, symptom control and comorbidity management. Methods. We studied an adult population screened for AF, where identified patients could enter a structured program of holistic and integrated care based on the ABC (Atrial fibrillation Better Care) pathway using mHealth with a mAFA intervention. In this cluster randomised trial, comparing mHeath intervention to usual care, the primary composite outcome was `stroke/thromboembolism, all-cause death and rehospitalization'. Results. The 1261 subjects (mean age 67.0 years, 38.0% female) who were followed up over one year (mean follow-up 687 (standard deviation, SD 191) days) in the intervention arm, had a lower risk of the composite outcome of 'ischaemic stroke/systemic thromboembolism, death, and rehospitalization' (hazard ratio, HR 0.18, 95% confidence interval, CI: 0.13-0.25, P < 0.001), compared to usual care (1212 subjects, mean age 70.1 years, 42.1% female). Of 842 patients using their smart devices for 'Better symptom management', 70.8% had good management adherence (monitoring time/follow-up since initial monitoring >= 70%), with the persistence of use of 91.7%. Conclusion. Amongst AF patients with long term use (>= 1 year) of mHealth technology for optimising stroke prevention, symptom control and comorbidity management, adherence/persistence was good and associated with a reduction in adverse clinical outcomes.
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