Journal
DRUG AND ALCOHOL DEPENDENCE
Volume 217, Issue -, Pages -Publisher
ELSEVIER IRELAND LTD
DOI: 10.1016/j.drugalcdep.2020.108336
Keywords
Opioid use disorder; Overdose; Economic evaluation; Cost-effectiveness; Simulation; Helping to end addiction long term; HEALing Communities Study
Categories
Funding
- National Institutes of Health (United States) through the NIH HEAL [UM1DA049406, UM1DA049412, UM1DA049415, UM1DA049417, UM1DA049394]
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Background: The HEALing Communities Study (HCS) is designed to implement and evaluate the Communities That HEAL (CTH) intervention, a conceptually driven framework to assist communities in selecting and adopting evidence-based practices to reduce opioid overdose deaths. The goal of the HCS is to produce generalizable information for policy makers and community stakeholders seeking to implement CTH or a similar community intervention. To support this objective, one aim of the HCS is a health economics study (HES), the results of which will inform decisions around fiscal feasibility and sustainability relevant to other community settings. Methods: The HES is integrated into the HCS design: an unblinded, multisite, parallel arm, cluster randomized, wait list-controlled trial of the CTH intervention implemented in 67 communities in four U.S. states: Kentucky, Massachusetts, New York, and Ohio. The objectives of the HES are to estimate the economic costs to communities of implementing and sustaining CTH; estimate broader societal costs associated with CTH; estimate the cost-effectiveness of CTH for overdose deaths avoided; and use simulation modeling to evaluate the short- and long-term health and economic impact of CTH, including future overdose deaths avoided and quality-adjusted life years saved, and to develop a simulation policy tool for communities that seek to implement CTH or a similar community intervention. Discussion: The HCS offers an unprecedented opportunity to conduct health economics research on solutions to the opioid crisis and to increase understanding of the impact and value of complex, community-level interventions.
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