Journal
CURRENT HYPERTENSION REPORTS
Volume 22, Issue 10, Pages -Publisher
SPRINGER
DOI: 10.1007/s11906-020-01088-4
Keywords
Preeclampsia; Placental dysfunction; Environmental exposure; Noise; Air pollution; Greenspaces
Categories
Funding
- Ramon y Cajal fellowship - Spanish Ministry of Economy and Competitiveness [RYC-2012-10995]
- Beatriu de Pinos fellowship - Universities and Research Secretariat of the Catalan Ministry of Business and Knowledge [2018/8374/I]
- PFIS (Contrato Predoctoral de Formacion en Investigacion en Salud) fellowship - Instituto de Salud Carlos III [FI17/00128]
- Spanish Ministry of Science and Innovation through the Centro de Excelencia Severo Ochoa 2019-2023 Program [CEX2018-000806-S]
- Generalitat de Catalunya through the CERCA Program
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Purpose of ReviewTo summarize the current knowledge of the pathophysiological implications and the clinical role of urban-related environmental exposures in pregnancy.Recent FindingsThe ongoing urbanization worldwide is leading to an increasing number of pregnant women being exposed to higher levels of urban-related environmental hazards such as air pollution and noise and, at the same time, having less contact with natural environments. Pregnancy represents a particular and vulnerable life period both for women and their children. Extensive physiological and metabolic changes, as well as changes to the cardiovascular and respiratory systems during pregnancy, could result in increased sensitivity to damage by environmental factors.SummaryExposure to air pollution and noise is associated with placental dysfunction and damage, which, in turn, could lead to maternal complications such as preeclampsia. In contrast, more contact with greenspace during pregnancy seems to mitigate these adverse impacts. These findings open up new challenges for our understanding of the potential effect of urban living on placental function and preeclampsia, and offer new clinical and research opportunities.
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