Visual and Refractive Outcomes with a New Topography-integrated Wavefront-guided Lasik Procedure

Purpose To evaluate the clinical outcomes of laser in situ keratomileusis (LASIK) using a new approach for the calculation of the ablation profile based on wavefront vertexing from pupil plane to corneal. Methods One hundred eyes of 50 patients (age, 21-41 years) with low and moderate myopia were enrolled in this prospective case series. All of them underwent topography-integrated wavefront-guided (TI-WFG) LASIK using the STAR S4IR excimer laser platform (Johnson & Johnson Vision). Visual, refractive, ocular aberrometric, ocular scattering index (OSI) and patient satisfaction outcomes were evaluated after a 90-day follow-up period. Astigmatic changes were evaluated by vector analysis. Results A significant reduction in sphere and cylinder (p< .001) was observed, with a significant improvement in uncorrected (UDVA) and corrected distance visual acuity (CDVA) (p< .001). Postoperative spherical equivalent was within +/- 0.50 and +/- 1.00 D in 91.1% (82/90) and 98.9% (89/90) of eyes, respectively. UDVA was 20/20 or better in 98.9% (89/90) of eyes. A total of 50.0% (45/90) of eyes gained 1 line of CDVA. Mean postoperative astigmatic correction index and angle of error were 1.01 +/- 0.56 and 0.17 +/- 0.18o. Postoperative high-order aberrometric coefficients were below 0.50 mu m in 92.2% (83/90) of eyes. Mean postoperative OSI was 0.71 +/- 0.44. All patients referred to be satisfied with the final outcomes and would recommend the procedure to their friends and relatives. Conclusions TI-WFG LASIK is a new approach for myopia and myopic astigmatism correction, with preservation of the ocular optical quality and high level of patient satisfaction associated.

Automated summary

The study evaluated the clinical outcomes of LASIK using a new approach for the calculation of the ablation profile based on wavefront vertexing from the pupil plane to the cornea. The results showed significant improvements in visual acuity, refractive outcomes, and patient satisfaction, making it an effective method for correcting myopia and myopic astigmatism while preserving ocular optical quality.