Journal
CURRENT ANALYTICAL CHEMISTRY
Volume 18, Issue 1, Pages 63-78Publisher
BENTHAM SCIENCE PUBL LTD
DOI: 10.2174/1573411016999200917161657
Keywords
Cancer biomarkers; electrochemical-based biosensor; surface modified electrode; carbon nanomaterial; metal nanoparticles; bioreceptors
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Early diagnosis of cancer is crucial for efficient treatment and reducing cancer related deaths. Nanomaterials integrated into biosensors offer rapid and sensitive detection of cancer biomarkers.
Diagnosis of cancer in the early stages can help treat efficiently and reduce cancer related death. Cancer biomarkers can respond to the presence of cancer in body fluids before the appearance of any other symptoms of cancer. The integration of nanomaterials into biosensors as electrochemical platforms offer rapid, sensitive detection for cancer biomarkers. The use of surface-modified electrodes by carbon nanomaterials and metal nanoparticles enhances the performance of electrochemical analysis in biosensing systems through the increase of bioreceptors loading capacity on the surface. In this review, novel approaches based on nanomaterial-modified systems in the point of care diagnostics are highlighted.
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