4.6 Review

Advanced engineering of third-generation lysins and formulation strategies for clinical applications

Related references

Note: Only part of the references are listed.
Article Pharmacology & Pharmacy

Comprehensive evaluation of chitosan nanoparticle based phage lysin delivery system; a novel approach to counter S. pneumoniae infections

Vijay Singh Gondil et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2020)

Review Microbiology

The global preclinical antibacterial pipeline

Ursula Theuretzbacher et al.

NATURE REVIEWS MICROBIOLOGY (2020)

Article Infectious Diseases

Antimicrobial activity of LysSS, a novel phage endolysin, against Acinetobacter baumannii and Pseudomonas aeruginosa

Shukho Kim et al.

JOURNAL OF GLOBAL ANTIMICROBIAL RESISTANCE (2020)

Article Multidisciplinary Sciences

Intracellular Staphylococcus aureus persisters upon antibiotic exposure

Frederic Peyrusson et al.

NATURE COMMUNICATIONS (2020)

Article Multidisciplinary Sciences

A VersaTile-driven platform for rapid hit-to-lead development of engineered lysins

H. Gerstmans et al.

SCIENCE ADVANCES (2020)

Article Infectious Diseases

Encapsulation of the Antistaphylococcal Endolysin LysRODI in pH-Sensitive Liposomes

Silvia Portilla et al.

ANTIBIOTICS-BASEL (2020)

Article Microbiology

Lysocins: Bioengineered Antimicrobials That Deliver Lysins across the Outer Membrane of Gram-Negative Bacteria

Ryan D. Heselpoth et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2019)

Article Biochemistry & Molecular Biology

The Influence of Dimerization on the Pharmacokinetics and Activity of an Antibacterial Enzyme Lysostaphin

Alexander V. Grishin et al.

MOLECULES (2019)

Article Nanoscience & Nanotechnology

Bioactive Silk Coatings Reduce the Adhesion of Staphylococcus aureus while Supporting Growth of Osteoblast-like Cells

Linnea Nileback et al.

ACS APPLIED MATERIALS & INTERFACES (2019)

Article Nanoscience & Nanotechnology

Synergistic Anti-Staphylococcal Activity Of Niosomal Recombinant Lysostaphin-LL-37

Somayeh Sadeghi et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2019)

Review Infectious Diseases

Analysis of the clinical antibacterial and antituberculosis pipeline

Ursula Theuretzbacher et al.

LANCET INFECTIOUS DISEASES (2019)

Review Biotechnology & Applied Microbiology

Engineering Microbial Living Therapeutics: The Synthetic Biology Toolbox

Danielle B. Pedrolli et al.

TRENDS IN BIOTECHNOLOGY (2019)

Review Biotechnology & Applied Microbiology

Synthetic biology of modular endolysins

Hans Gerstmans et al.

BIOTECHNOLOGY ADVANCES (2018)

Article Biochemistry & Molecular Biology

Preparation, characterization and efficacy of lysostaphin-chitosan gel against Staphylococcus aureus

Sai Nithya et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2018)

Review Dermatology

Skin wound healing in humans and mice: Challenges in translational research

Helena D. Zomer et al.

JOURNAL OF DERMATOLOGICAL SCIENCE (2018)

Article Multidisciplinary Sciences

Hydrogel delivery of lysostaphin eliminates orthopedic implant infection by Staphylococcus aureus and supports fracture healing

Christopher T. Johnson et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Article Microbiology

Effects of Phage Endolysin SAL200 Combined with Antibiotics on Staphylococcus aureus Infection

Nak-Hyun Kim et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2018)

Review Biotechnology & Applied Microbiology

Nanoemulsions in drug delivery: formulation to medical application

Hossam H. Tayeb et al.

NANOMEDICINE (2018)

Article Virology

Safety Studies of Pneumococcal Endolysins Cpl-1 and Pal

Marek Harhala et al.

VIRUSES-BASEL (2018)

Correction Biotechnology & Applied Microbiology

Identification of Peptidoglycan Hydrolase Constructs with Synergistic Staphylolytic Activity in Cow's Milk (vol 83, 2017)

Carolin T. Verbree et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2018)

Review Microbiology

Pseudomonas predators: understanding and exploiting phage-host interactions

Jeroen De Smet et al.

NATURE REVIEWS MICROBIOLOGY (2017)

Review Critical Care Medicine

Early pathogenic colonisers of acute burn wounds: A retrospective review

Hye-Sung Park et al.

BURNS (2017)

Article Microbiology

Efficacy of Artilysin Art-175 against Resistant and Persistent Acinetobacter baumannii

Valerie Defraine et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2016)

Letter Pharmacology & Pharmacy

Pharmacokinetics of the phage endolysin-based candidate drug SAL200 in monkeys and its appropriate intravenous dosing period

Soo Youn Jun et al.

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2016)

Article Biotechnology & Applied Microbiology

T4 lysozyme fused with cellulose-binding module for antimicrobial cellulosic wound dressing materials

A. Abouhmad et al.

JOURNAL OF APPLIED MICROBIOLOGY (2016)

Review Chemistry, Medicinal

PEGylation of Biopharmaceuticals: A Review of Chemistry and Nonclinical Safety Information of Approved Drugs

Peter L. Turecek et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2016)

Review Infectious Diseases

Alternatives to antibiotics-a pipeline portfolio review

Lloyd Czaplewski et al.

LANCET INFECTIOUS DISEASES (2016)

Article Multidisciplinary Sciences

A secreted bacterial peptidoglycan hydrolase enhances tolerance to enteric pathogens

Kavita J. Rangan et al.

SCIENCE (2016)

Article Multidisciplinary Sciences

Triple-acting Lytic Enzyme Treatment of Drug-Resistant and Intracellular Staphylococcus aureus

Stephen C. Becker et al.

SCIENTIFIC REPORTS (2016)

Article Infectious Diseases

Incidence of skin and soft tissue infections in ambulatory and inpatient settings, 2005-2010

Loren G. Miller et al.

BMC INFECTIOUS DISEASES (2015)

Article Critical Care Medicine

Epidemiology of Clinically Relevant Bacterial Pathogens in a Burn Center in the Netherlands Between 2005 and 2011

Bram M. W. Diederen et al.

JOURNAL OF BURN CARE & RESEARCH (2015)

Article Biochemical Research Methods

Development and validation of a broad scheme for prediction of HLA class II restricted T cell epitopes

Sinu Paul et al.

JOURNAL OF IMMUNOLOGICAL METHODS (2015)

Review Medicine, General & Internal

Community-acquired pneumonia: An overview

Lionel A. Mandell

POSTGRADUATE MEDICINE (2015)

Article Medicine, Research & Experimental

Structure-based redesign of lysostaphin yields potent antistaphylococcal enzymes that evade immune cell surveillance

Kristina Blazanovic et al.

MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT (2015)

Article Biotechnology & Applied Microbiology

Expression and delivery of an endolysin to combat Clostridium perfringens

Teresa Gervasi et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2014)

Review Biochemistry & Molecular Biology

Animal models in burn research

A. Abdullahi et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2014)

Article Biotechnology & Applied Microbiology

Chitosan-protein scaffolds loaded with lysostaphin as potential antistaphylococcal wound dressing materials

P. Szweda et al.

JOURNAL OF APPLIED MICROBIOLOGY (2014)

Article Multidisciplinary Sciences

Effective Removal of Staphylococcal Biofilms by the Endolysin LysH5

Diana Gutierrez et al.

PLOS ONE (2014)

Article Dermatology

Effects of potassium apigenin and verbena extract on the wound healing process of SKH-1 mouse skin

Pia Lopez-Jornet et al.

INTERNATIONAL WOUND JOURNAL (2014)

Article Agriculture, Dairy & Animal Science

Site-Specific N-Glycosylation of Caprine Lysostaphin Restricts its Bacteriolytic Activity Toward Staphylococcus Aureus

Ching-Ying Huang et al.

ANIMAL BIOTECHNOLOGY (2013)

Review Immunology

Pathways of Antigen Processing

Janice S. Blum et al.

ANNUAL REVIEW OF IMMUNOLOGY, VOL 31 (2013)

Article Infectious Diseases

Delivery of the endolysin Cpl-1 by inhalation rescues mice with fatal pneumococcal pneumonia

Jan M. Doehn et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2013)

Article Biochemical Research Methods

Structure-Guided Deimmunization of Therapeutic Proteins

Andrew S. Parker et al.

JOURNAL OF COMPUTATIONAL BIOLOGY (2013)

Review Biotechnology & Applied Microbiology

Platforms for antibiotic discovery

Kim Lewis

NATURE REVIEWS DRUG DISCOVERY (2013)

Article Medicine, Research & Experimental

Effect of PEGylation on Protein Hydrodynamics

Yatin R. Gokarn et al.

MOLECULAR PHARMACEUTICS (2012)

Article Multidisciplinary Sciences

Structural engineering of a phage lysin that targets Gram-negative pathogens

Petra Lukacik et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Review Cell Biology

Biomaterial-Associated Infection: Locating the Finish Line in the Race for the Surface

Henk J. Busscher et al.

SCIENCE TRANSLATIONAL MEDICINE (2012)

Review Immunology

Epithelial antimicrobial defence of the skin and intestine

Richard L. Gallo et al.

NATURE REVIEWS IMMUNOLOGY (2012)

Review Microbiology

Biology of Clostridium difficile: Implications for Epidemiology and Diagnosis

Karen C. Carroll et al.

ANNUAL REVIEW OF MICROBIOLOGY, VOL 65 (2011)

Article Biotechnology & Applied Microbiology

Inhibition of Staphylococcus aureus by Lysostaphin-Expressing Lactobacillus plantarum WCFS1 in a Modified Genital Tract Secretion Medium

Huanli Liu et al.

APPLIED AND ENVIRONMENTAL MICROBIOLOGY (2011)

Article Biotechnology & Applied Microbiology

Antibacterial activity of Acinetobacter baumannii phage ΦAB2 endolysin (LysAB2) against both Gram-positive and Gram-negative bacteria

Meng-Jiun Lai et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2011)

Review Biochemical Research Methods

Strategies for extended serum half-life of protein therapeutics

Roland E. Kontermann

CURRENT OPINION IN BIOTECHNOLOGY (2011)

Review Biotechnology & Applied Microbiology

Novel insights into the epidemiology of Clostridium perfringens type A food poisoning

Miia Lindstrom et al.

FOOD MICROBIOLOGY (2011)

Article Biochemical Research Methods

Predicting MHC-II Binding Affinity Using Multiple Instance Regression

Yasser EL-Manzalawy et al.

IEEE-ACM TRANSACTIONS ON COMPUTATIONAL BIOLOGY AND BIOINFORMATICS (2011)

Article Infectious Diseases

A stable phage lysin (Cpl-1) dimer with increased antipneumococcal activity and decreased plasma clearance

Gregory Resch et al.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2011)

Review Biotechnology & Applied Microbiology

Surgical Approaches to Create Murine Models of Human Wound Healing

VictorW. Wong et al.

JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY (2011)

Article Biotechnology & Applied Microbiology

PEGylating a bacteriophage endolysin inhibits its bactericidal activity

Gregory Resch et al.

AMB EXPRESS (2011)

Review Chemistry, Multidisciplinary

Cellulose Nanocrystals: Chemistry, Self-Assembly, and Applications

Youssef Habibi et al.

CHEMICAL REVIEWS (2010)

Article Biotechnology & Applied Microbiology

Highly glycosylated human alpha interferon: An insight into a new therapeutic candidate

Natalia Ceaglio et al.

JOURNAL OF BIOTECHNOLOGY (2010)

Article Microbiology

LysK CHAP endopeptidase domain is required for lysis of live staphylococcal cells

Stephen C. Becker et al.

FEMS MICROBIOLOGY LETTERS (2009)

Review Microbiology

Staphylococcus epidermidis - the 'accidental' pathogen

Michael Otto

NATURE REVIEWS MICROBIOLOGY (2009)

Article Medicine, General & Internal

National trends in ambulatory visits and antibiotic prescribing for skin and soft-tissue infections

Adam L. Hersh et al.

ARCHIVES OF INTERNAL MEDICINE (2008)

Article Biochemistry & Molecular Biology

Engineering of a femtomolar affinity binding protein to human serum albumin

Andreas Jonsson et al.

PROTEIN ENGINEERING DESIGN & SELECTION (2008)

Article Biochemical Research Methods

Protein engineers turned evolutionists

Sergio G. Peisajovich et al.

NATURE METHODS (2007)

Review Microbiology

Carbohydrate binding modules: Biochemical properties and novel applications

Oded Shoseyov et al.

MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS (2006)

Article Biochemistry & Molecular Biology

Peptidoglycan hydrolytic activities associated with bacteriophage virions

M Moak et al.

MOLECULAR MICROBIOLOGY (2004)

Article Microbiology

Lysostaphin-coated catheters eradicate Staphylococccus aureus challenge and block surface colonization

A Shah et al.

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2004)

Article Biotechnology & Applied Microbiology

Bacillus amyloliquefaciens phage endolysin can enhance permeability of Pseudomonas aeruginosa outer membrane and induce cell lysis

Y Orito et al.

APPLIED MICROBIOLOGY AND BIOTECHNOLOGY (2004)

Article Immunology

Phage lytic enzyme Cpl-1 as a novel antimicrobial for pneumococcal bacteremia

JM Loeffler et al.

INFECTION AND IMMUNITY (2003)

Article Multidisciplinary Sciences

Prevention and elimination of upper respiratory colonization of mice by group A streptococci by using a bacteriophage lytic enzyme

D Nelson et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)

Review Microbiology

Toxic shock syndrome and bacterial superantigens: An update

JK McCormick et al.

ANNUAL REVIEW OF MICROBIOLOGY (2001)