Recent Application of Deep Eutectic Solvents as Green Solvent in Dispersive Liquid-Liquid Microextraction of Trace Level Chemical Contaminants in Food and Water

As growing concerns on green, cost-effective, and time-saving chemistry analysis methods, deep eutectic solvents (DESs) are considered to be promising green alternatives to conventional solvents in dispersive liquid-liquid microextraction (DLLME) of trace level chemical contaminants in food and water, due to their biodegradability, low cost, and simple preparation. In the past few years, numerous innovative researches have focused on preconcentration of trace level chemical contaminants using DESs as extractant. In this context, this review aims to summarize the updated state-of-the-art effort dedicated to preconcentration of trace level chemical contaminants in food and water sample using DESs as extractants in DLLME. Furthermore, the major impact factors affecting the preconcentration efficiency and process mechanisms are thoroughly analyzed and discussed. Finally, prospects and challenges in application of DESs as solvents in DLLME to enrich trace level chemical contaminants are extensively elucidated and critically reviewed.

Automated summary

This review summarizes the latest research progress on using DES as solvents for preconcentration of trace level chemical contaminants in DLLME. The major impact factors affecting the preconcentration efficiency and process mechanisms are analyzed and discussed. Furthermore, the prospects and challenges of using DES as solvents for enriching trace level chemical contaminants in DLLME are extensively elucidated and critically reviewed.