Journal
COMPUTING IN SCIENCE & ENGINEERING
Volume 22, Issue 5, Pages 72-81Publisher
IEEE COMPUTER SOC
DOI: 10.1109/MCSE.2019.2923974
Keywords
Scattering; Microscopy; Image reconstruction; Three-dimensional displays; Object oriented modeling; Analytical models; Data models; G; 1; 8; g Inverse problems; I; 4; 0; b Image processing software; I; 4; 1; b Imaging geometry; 5; 1; e Statistical; J; 2 Physical Sciences and Engineering
Funding
- National Science Foundation [DMR-1306410, DMR-1420570]
- Alfred P. Sloan Research Fellowship
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A holographic microscope captures interference patterns, or holograms, that encode three-dimensional (3-D) information about the object being viewed. Computation is essential to extract that 3-D information. By wrapping low-level scattering codes and taking advantage of Python's data analysis ecosystem, HoloPy makes it easy for experimentalists to use modern, sophisticated inference methods to analyze holograms. The resulting data can be used to understand how small particles or microorganisms move and interact. The project illustrates how computational tools can enable experimental methods and new experiments.
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