Journal
COMPUTER METHODS IN BIOMECHANICS AND BIOMEDICAL ENGINEERING
Volume 24, Issue 2, Pages 215-229Publisher
TAYLOR & FRANCIS LTD
DOI: 10.1080/10255842.2020.1821193
Keywords
Abdominal aortic aneurysm; intraluminal thrombus; porous media; oxygen transport; hypoxia
Funding
- Faculty Development Fund
- Duquesne University
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This paper presents a modeling and simulation study of mass and momentum transport through the arterial lumen and the porous arterial wall of an abdominal aortic aneurysm (AAA). The authors introduce a novel coupled fluid-porous structure-mass transport model to address the impact of porous structure and intramural flow on oxygen concentration in the aneurysmal wall. Computational simulations provide insights into filtration velocity and oxygen concentration in the artery, revealing the essential coupling between blood and filtration flow and how it influences oxygen transport.
This paper reports on modelling and simulation of the coupled mass and momentum transport through the arterial lumen and the porous arterial wall of an abdominal aortic aneurysm (AAA). The effect of porous structure and intramural flow, which is usually neglected, is essential to quantify the oxygen concentration in the aneurysmal wall and will be addressed in this work via a novel coupled fluid-porous structure-mass transport model for AAA. The computational solver provides a prediction of the filtration velocity and oxygen concentration in the artery and further simulations are used to investigate the relation between the wall oxygen concentration and permeability. The results demonstrate the essential coupling between blood and filtration flow and specifically how their interactions affect oxygen transport.
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