Journal
COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY
Volume 19, Issue 6, Pages 2797-2842Publisher
WILEY
DOI: 10.1111/1541-4337.12638
Keywords
aflatoxins; Aspergillus flavus; biosynthesis; food safety; secondary metabolites
Categories
Funding
- Ghent University 'Special Research Fund' (BOF) [BOF.EXP.2017.0001.01_MSsmall]
Ask authors/readers for more resources
Filamentous fungi represent a rich source of extrolites, including secondary metabolites (SMs) comprising a great variety of astonishing structures and interesting bioactivities. State-of-the-art techniques in genome mining, genetic manipulation, and secondary metabolomics have enabled the scientific community to better elucidate and more deeply appreciate the genetic and biosynthetic chemical arsenal of these microorganisms.Aspergillus flavusis best known as a contaminant of food and feed commodities and a producer of the carcinogenic family of SMs, aflatoxins. This fungus produces many SMs including polyketides, ribosomal and nonribosomal peptides, terpenoids, and other hybrid molecules. This review will discuss the chemical diversity, biosynthetic pathways, and biological/ecological role ofA. flavusSMs, as well as their significance concerning food safety and security.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available