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NATURE REVIEWS CANCER (2009)
Long-term survival after pancreatoduodenectomy for pancreatic adenocarcinoma - Is cure possible?
Thomas Schnelldorfer et al.
ANNALS OF SURGERY (2008)
Pancreatic stellate cells: Partners in crime with pancreatic cancer cells
Alain Vonlaufen et al.
CANCER RESEARCH (2008)
Cancer-associated stroma fibroblasts promote pancreatic tumor progression
Rosa F. Hwang et al.
CANCER RESEARCH (2008)
Structures and biological functions of IL-31 and IL-31 receptors
Qing Zhang et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2008)
Mesothelin targeted cancer immunotherapy
Raffit Hassan et al.
EUROPEAN JOURNAL OF CANCER (2008)
The SOCS box domain of SOCS3: Structure and interaction with the elonginBC-cullin5 ubiquitin ligase
Jeffrey J. Babon et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
The role of the tumor microenvironment in the progression of pancreatic cancer
Buckminster Farrow et al.
JOURNAL OF SURGICAL RESEARCH (2008)
Notch and Kras reprogram pancreatic acinar cells to ductal intraepithelial neoplasia
De La O. Jean-Paul et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Spontaneous induction of murine pancreatic intraepithelial neoplasia (mPanIN) by acinar cell targeting of oncogenic Kras in adult mice
Nils Habbe et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Oncogenic Ras-induced secretion of IL6 is required for tumorigenesis
Brooke Ancrile et al.
GENES & DEVELOPMENT (2007)
IL-6 stimulates Th2 type cytokine secretion and upregulates VEGF and NRP-1 expression in pancreatic cancer cells
Louis W. Feurino et al.
CANCER BIOLOGY & THERAPY (2007)
Elevated interleukin-6 and G-CSF in human pancreatic cancer cell conditioned medium suppress dendritic cell differentiation and activation
Uddalak Bharadwaj et al.
CANCER RESEARCH (2007)
Erlotinib plus gemcitabine compared with gemcitabine alone in patients with advanced pancreatic cancer: A phase III trial of the National Cancer Institute of Canada clinical trials group
Malcolm J. Moore et al.
JOURNAL OF CLINICAL ONCOLOGY (2007)
The dynamics of signal triggering in a gp130-receptor complex
Rishi Matadeen et al.
STRUCTURE (2007)
Identification of pancreatic cancer stem cells
Chenwei Li et al.
CANCER RESEARCH (2007)
Inhibition of STAT3 activity with AG490 decreases the invasion of human pancreatic cancer cells in vitro
Chen Huang et al.
CANCER SCIENCE (2006)
Cytokine expression profile in human pancreatic carcinoma cells and in surgical specimens: implications for survival
G Bellone et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2006)
Phylogeny and evolution of class-I helical cytokines
MO Huising et al.
JOURNAL OF ENDOCRINOLOGY (2006)
Role of mononuclear cells and inflammatory cytokines in pancreatic cancer-related cachexia
ME Martignoni et al.
CLINICAL CANCER RESEARCH (2005)
Experimental trial for diagnosis of pancreatic ductal carcinoma based on gene expression profiles of pancreatic ductal cells
M Ishikawa et al.
CANCER SCIENCE (2005)
Expression of HOXB2, a retinoic acid signaling target in pancreatic cancer and pancreatic intraepithelial neoplasia
D Segara et al.
CLINICAL CANCER RESEARCH (2005)
Trp53R172H and KraSG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice
SR Hingorani et al.
CANCER CELL (2005)
Pancreatic carcinoma cells induce fibrosis by stimulating proliferation and matrix synthesis of stellate cells
MG Bachem et al.
GASTROENTEROLOGY (2005)
Neuropoietin, a new IL-6-related cytokine signaling through the ciliary neurotrophic factor receptor
D Derouet et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27
S Pflanz et al.
JOURNAL OF IMMUNOLOGY (2004)
An illustrated consensus on the classification of pancreatic Intraepithelial neoplasia and intraductal papillary mucinous neoplasms
RH Hruban et al.
AMERICAN JOURNAL OF SURGICAL PATHOLOGY (2004)
Cytokines in pancreatic carcinoma - Correlation with phenotypic characteristics and prognosis
B Ebrahimi et al.
CANCER (2004)
New IL-6 (gp130) family cytokine members, CLC/NNT1/BSF3 and IL-27
M Murakami et al.
GROWTH FACTORS (2004)
Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse
SR Hingorani et al.
CANCER CELL (2003)
Activated signal transducer and activator of transcription 3 (STAT3) supports the malignant phenotype of human pancreatic cancer
A Scholz et al.
GASTROENTEROLOGY (2003)
Principles of interleukin (IL)-6-type cytokine signalling and its regulation
PC Heinrich et al.
BIOCHEMICAL JOURNAL (2003)
Role of stromal-derived cytokines and growth factors in bone metastasis
GD Roodman
CANCER (2003)
Stat3 activation regulates the expression of vascular endothelial growth factor and human pancreatic cancer angiogenesis and metastasis
DY Wei et al.
ONCOGENE (2003)
SHP2 and SOCS3 contribute to Tyr-759-dependent attenuation of interleukin-6 signaling through gp130
U Lehmann et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo
JG Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
The SOCS box of SOCS-1 accelerates ubiquitin-dependent proteolysis of TEL-JAK2
S Kamizono et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Soluble gp130 is the natural inhibitor of soluble interleukin-6 receptor transsignaling responses
T Jostock et al.
EUROPEAN JOURNAL OF BIOCHEMISTRY (2001)
Interleukin-11 signals through the formation of a hexameric receptor complex
VA Barton et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Signal transduction of IL-6, leukemia-inhibitory factor, and oncostatin M: Structural receptor requirements for signal attenuation
D Anhuf et al.
JOURNAL OF IMMUNOLOGY (2000)
Cytokines and advanced cancer
RJ Dunlop et al.
JOURNAL OF PAIN AND SYMPTOM MANAGEMENT (2000)
Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130
SE Nicholson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
SOCS3 exerts its inhibitory function on interleukin-6 signal transduction through the SHP2 recruitment site of gp130
J Schmitz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
The cytoplasmic tyrosine motifs is full-length glycoprotein 130 have different roles in IL-6 signal transduction
J Schmitz et al.
JOURNAL OF IMMUNOLOGY (2000)