Oligodendroglioma in 68Ga-PSMA-11 and 18F-Fluciclovine PET/CT

Prostate cancer (PC) is one of the most common cancers affecting men worldwide, with a high recurrence rate after therapy. Ga-68-PSMA-11 and F-18-fluciclovine are PET imaging tracers for the detection of recurrence sites in PC patients. Ga-68-PSMA-11 is a membrane antigen overexpressed by tumor cells, whereas F-18-fluciclovine targets increased amino acid transporter in the membrane of cancer cells. We report a case of an 83-year-old man with known oligodendroglioma and biochemically recurrent PC who shows a high focal Ga-68-PSMA-11 and F-18-fluciclovine uptake in the brain.

Automated summary

Prostate cancer is a common cancer in men with high recurrence rate, and Ga-68-PSMA-11 and F-18-fluciclovine are PET imaging tracers used to detect recurrence sites. In a case study, an 83-year-old man with known oligodendroglioma and biochemically recurrent PC showed high focal uptake of Ga-68-PSMA-11 and F-18-fluciclovine in the brain.