Journal
CLINICAL MEDICINE
Volume 20, Issue 5, Pages 513-516Publisher
ROY COLL PHYS LONDON EDITORIAL OFFICE
DOI: 10.7861/clinmed.2020-0697
Keywords
Primary biliary cholangitis; primary sclerosing cholangitis; risk stratification; ursodeoxycholic acid; cholangiocarcinoma
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Cholestatic liver diseases are a challenging spectrum of conditions arising from damage to bile ducts, leading to build-up of bile acids and inflammatory processes that cause injury to cholangiocytes and hepatocytes. Primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC) are the two most common cholestatic disorders. In this review we detail the latest guidelines for the diagnosis and management of patients with these two conditions.
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