Journal
CLINICAL LUNG CANCER
Volume 22, Issue 4, Pages E584-E594Publisher
CIG MEDIA GROUP, LP
DOI: 10.1016/j.cllc.2020.10.008
Keywords
Body composition; Clinical nutrition; CT scan; Malnutrition; Muscle mass; Personalized nutrition
Categories
Funding
- Associazione Italiana per la Ricerca sul Cancro (AIRC) [IG20583]
- AIRC [IG18599]
- AIRC 5x1000 [21052]
- Institutional funds of Universita Cattolica del Sacro Cuore (UCSC) [D12018/2019]
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Lung cancer patients commonly experience malnutrition, a problem often underestimated in clinical settings. The role of nutritional interventions in these patients is not strongly proven, necessitating further research for confirmation.
Lung cancer (LC) represents the most commonly diagnosed neoplasm worldwide for both sexes and is the leading cause of cancer mortality. Malnutrition is a comorbidity frequently found in neoplastic patients, but it remains often underestimated and thus undertreated. In this review, we aimed to investigate the incidence of malnutrition among LC patients according to different screening and assessment tools, to evaluate the impact of weight loss and body composition on survival, and to analyze the efficacy of different nutritional interventions in this setting. Although malnutrition, weight loss, and body composition changes can affect survival and other clinical outcomes in LC patients, the role of nutritional interventions is not yet strongly proven, and further studies are recommended. Nevertheless, screening, assessing, and eventually treating malnutrition in LC patients are strongly recommended, according to the most recent nutritional intervention guidelines for oncology patients.
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