Related references
Note: Only part of the references are listed.Natural Products as Sources of New Drugs over the Nearly Four Decades from 01/1981 to 09/2019
David J. Newman et al.
JOURNAL OF NATURAL PRODUCTS (2020)
Cheminformatics Analysis of Natural Product Scaffolds: Comparison of Scaffolds Produced by Animals, Plants, Fungi and Bacteria
Peter Ertl et al.
MOLECULAR INFORMATICS (2020)
A Method for the Stereoselective Construction of the Hemiaminal Center in Zampanolides
Tobias M. Bruetsch et al.
ORGANIC LETTERS (2020)
Have marine natural product drug discovery efforts been productive and how can we improve their efficiency?
Florbela Pereira
EXPERT OPINION ON DRUG DISCOVERY (2019)
Synthesis, conformational preferences, and biological activity of conformational analogues of the microtubule-stabilizing agents, (-)-zampanolide and (-)-dactylolide
Jeffrey L. Henry et al.
MEDCHEMCOMM (2019)
Synthesis and antiproliferative evaluation of new zampanolide mimics
Guanglin Chen et al.
ORGANIC & BIOMOLECULAR CHEMISTRY (2019)
Optimized synthesis and antiproliferative activity of desTHPdactylolides
Guanglin Chen et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2018)
Recent advances in microtubule-stabilizing agents
Ya-Nan Cao et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
Marine Natural Products in Medicinal Chemistry
Carlos Jimenez
ACS MEDICINAL CHEMISTRY LETTERS (2018)
Retrospective analysis of natural products provides insights for future discovery trends
Cameron R. Pye et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Drugs from the Oceans: Marine Natural Products as Leads for Drug Discovery
Karl-Heinz Altmann
CHIMIA (2017)
Molecular Mechanism of Action of Microtubule-Stabilizing Anticancer Agents
Andrea E. Prota et al.
SCIENCE (2013)
Zampanolide, a Potent New Microtubule-Stabilizing Agent, Covalently Reacts with the Taxane Luminal Site in Tubulin α,β-Heterodimers and Microtubules
Jessica J. Field et al.
CHEMISTRY & BIOLOGY (2012)
Lessons from the Past and Charting the Future of Marine Natural Products Drug Discovery and Chemical Biology
William H. Gerwick et al.
CHEMISTRY & BIOLOGY (2012)
Total Synthesis of (-)-Zampanolide and Structure-Activity Relationship Studies on (-)-Dactylolide Derivatives
Didier Zurwerra et al.
CHEMISTRY-A EUROPEAN JOURNAL (2012)
Total Synthesis of Potent Antitumor Macrolide (-)-Zampanolide: An Oxidative Intramolecular Cyclization-Based Strategy
Arun K. Ghosh et al.
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY (2012)
Isopropenyl acetate, a remarkable, cheap and acylating agent of amines under solvent- and catalyst-free conditions: a systematic investigation
Romina Pelagalli et al.
GREEN CHEMISTRY (2012)
Isolation, biological activity, synthesis, and medicinal chemistry of the pederin/mycalamide family of natural products
R. Adam Mosey et al.
NATURAL PRODUCT REPORTS (2012)
Marine natural products: a new wave of drugs?
Rana Montaser et al.
FUTURE MEDICINAL CHEMISTRY (2011)
Enantioselective Total Synthesis of (-)-Zampanolide, a Potent Microtubule-Stabilizing Agent
Arun K. Ghosh et al.
ORGANIC LETTERS (2011)
An Enantioselective Total Synthesis of (+)-Peloruside A
Meredeth A. McGowan et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2010)
Microtubule-binding agents: a dynamic field of cancer therapeutics
Charles Dumontet et al.
NATURE REVIEWS DRUG DISCOVERY (2010)
Synthesis of (-)-Dactylolide and 13-Desmethylene-(-)-dactylolide and Their Effects on Tubulin
Didier Zurwerra et al.
ORGANIC LETTERS (2010)
Microtubule-Stabilizing Activity of Zampanolide, a Potent Macrolide Isolated from the Tongan Marine Sponge Cacospongia mycofijiensis
Jessica J. Field et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Novel Chemical Space Exploration via Natural Products
Josefin Rosen et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Total Synthesis of (-)-Zampanolide and Questionable Existence of (-)-Dactylolide as the Elusive Biosynthetic Precursor of (-)-Zampanolide in an Okinawan Sponge
Jun'ichi Uenishi et al.
ORGANIC LETTERS (2009)
Optimization of taxane binding to microtubules: Binding affinity dissection and incremental construction of a high-affinity analog of paclitaxel
Ruth Matesanz et al.
CHEMISTRY & BIOLOGY (2008)
Total synthesis of (-)-dactylolide and formal synthesis of (-)-zampanolide via target oriented β-C-glycoside formation
Fei Ding et al.
JOURNAL OF ORGANIC CHEMISTRY (2008)
A Straightforward Synthesis of Enantiopure 2,6-Disubstituted Morpholines by a Regioselective O-Protection/Activation Protocol
Michele Penso et al.
SYNLETT (2008)
Overcoming tumor drug resistance with high-affinity taxanes: A SAR study of C2-modified 7-acyl-10-deacetyl cephalomannines
Chun-Gang Yang et al.
CHEMMEDCHEM (2007)
Cheminformatic analysis of natural products and their chemical space
Stefan Wetzel et al.
CHIMIA (2007)
Interaction of epothilone analogs with the paclitaxel binding site:: Relationship between binding affinity, microtubule stabilization, and cytotoxicity
RM Buey et al.
CHEMISTRY & BIOLOGY (2004)
Macrolactonization via Ti(IV)-mediated epoxy-acid coupling: A total synthesis of (-)-dactylolide [and zampanolide]
TR Hoye et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
Total syntheses of (+)-zampanolide and (+)-dactylolide exploiting a unified strategy
AB Smith et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2002)
Total synthesis of (+)-zampanolide
AB Smith et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2001)
Chemical synthesis and biological properties of pyridine epothilones
KC Nicolaou et al.
CHEMISTRY & BIOLOGY (2000)
Share Paper
