4.3 Article

Mycobacterium alvei (ω-1)-methoxy mycolic acids: Absolute stereochemistry and synthesis

Journal

CHEMISTRY AND PHYSICS OF LIPIDS
Volume 233, Issue -, Pages -

Publisher

ELSEVIER IRELAND LTD
DOI: 10.1016/j.chemphyslip.2020.104977

Keywords

Mycobacterium; Alvei; Mycolic acid; (omega-1)-Methoxy; Synthesis

Funding

  1. Saudi Arabia Ministry of Higher Education
  2. Shaqra University
  3. Iraqi Ministry of Higher Education and Scientific Research - University of Mosul

Ask authors/readers for more resources

Cells of Mycobacterium alvei are known to contain a unique set of mycolic acids with a (omega-1)-methoxy group; although the various enzymes in the biosynthesis of other types of mycolic acid have been widely studied, the biosynthetic route to this substituent is unclear. We now define the stereochemistry of the (omega-1)-methoxy fragment as R, and describe the synthesis of a major R-(omega-1)-methoxy-mycolic acid and its sugar esters, and of two natural M. alvei diene mycolic acids.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.3
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available