Journal
CHEMIE INGENIEUR TECHNIK
Volume 92, Issue 11, Pages 1780-1789Publisher
WILEY-V C H VERLAG GMBH
DOI: 10.1002/cite.202000046
Keywords
Eicosapentaenoic acid; Carotenoids; Diatom; Light availability; Pressurized liquid extraction
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Funding
- Ministry of Science, Research and the Arts of Baden-Wuerttemberg (MWK), Germany, as part of the BBW ForWerts Graduate Program [7533-10-5/91/2]
- MWK
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Eicosapentaenoic acid (EPA) and fucoxanthin, a carotenoid, provide a broad variety of health benefits in human nutrition. In this study, an up- and downstream process for the coproduction of EPA and fucoxanthin using the diatomPhaeodactylum tricornutumin flat-panel airlift photobioreactors is proposed. The approach represents a promising alternative to conventional sources for both compounds, viz. marine fish and macroalgae. The productivity as well as the biomass-specific product content were optimized during cultivation. Subsequently, both compounds were extracted, separated and purified using pressurized liquids.
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