Journal
CELL RESEARCH
Volume 30, Issue 10, Pages 831-832Publisher
SPRINGERNATURE
DOI: 10.1038/s41422-020-00396-3
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Funding
- NIAID NIH HHS [U19 AI133524, P01 AI056299] Funding Source: Medline
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In a new study in Nature, Zhou et al. identify IL-18BP as a novel soluble immune checkpoint, and describe engineering of a decoy-resistant IL-18 to overcome this barrier and drive potent anti-tumor immunity.
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