4.7 Article

Impaired RIPK1 ubiquitination sensitizes mice to TNF toxicity and inflammatory cell death

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

RIP1 inhibition blocks inflammatory diseases but not tumor growth or metastases

Snahel Patel et al.

CELL DEATH AND DIFFERENTIATION (2020)

Review Cell Biology

Distinct modes of TNF signaling through its two receptors in health and disease

Kamar-Sulu N. Atretkhany et al.

JOURNAL OF LEUKOCYTE BIOLOGY (2020)

Article Multidisciplinary Sciences

Mutations that prevent caspase cleavage of RIPK1 cause autoinflammatory disease

Najoua Lalaoui et al.

NATURE (2020)

Article Multidisciplinary Sciences

A dominant autoinflammatory disease caused by non-cleavable variants of RIPK1

Panfeng Tao et al.

NATURE (2020)

Review Biochemistry & Molecular Biology

SMAC mimetics and RIPK inhibitors as therapeutics for chronic inflammatory diseases

Simone Jensen et al.

SCIENCE SIGNALING (2020)

Review Pharmacology & Pharmacy

Inhibitors Targeting RIPK1/RIPK3: Old and New Drugs

Sofie Martens et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2020)

Review Immunology

Cell Death and Inflammation - A Vital but Dangerous Liaison

Nieves Peltzer et al.

TRENDS IN IMMUNOLOGY (2019)

Article Multidisciplinary Sciences

Serine 25 phosphorylation inhibits RIPK1 kinase-dependent cell death in models of infection and inflammation

Yves Dondelinger et al.

NATURE COMMUNICATIONS (2019)

Article Multidisciplinary Sciences

Cleavage of RIPK1 by caspase-8 is crucial for limiting apoptosis and necroptosis

Kim Newton et al.

NATURE (2019)

Review Neurosciences

Necroptosis and RIPK1-mediated neuroinflammation in CNS diseases

Junying Yuan et al.

NATURE REVIEWS NEUROSCIENCE (2019)

Article Biochemistry & Molecular Biology

Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2

Alessandro Annibaldi et al.

MOLECULAR CELL (2018)

Article Multidisciplinary Sciences

Regulation of a distinct activated RIPK1 intermediate bridging complex I and complex II in TNFα-mediated apoptosis

Palak Amin et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)

Article Biochemistry & Molecular Biology

Coordinated ubiquitination and phosphorylation of RIP1 regulates necroptotic cell death

M. Cristina de Almagro et al.

CELL DEATH AND DIFFERENTIATION (2017)

Article Multidisciplinary Sciences

PELI1 functions as a dual modulator of necroptosis and apoptosis by regulating ubiquitination of RIPK1 and mRNA levels of c-FLIP

Huibing Wang et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Article Multidisciplinary Sciences

Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis

Jiefei Geng et al.

NATURE COMMUNICATIONS (2017)

Review Biochemistry & Molecular Biology

Diverse ubiquitin linkages regulate RIP kinases-mediated inflammatory and cell death signaling

Axel Witt et al.

CELL DEATH AND DIFFERENTIATION (2017)

Review Immunology

The diverse role of RIP kinases in necroptosis and inflammation

John Silke et al.

NATURE IMMUNOLOGY (2015)

Review Cell Biology

RIPK1 and RIPK3: critical regulators of inflammation and cell death

Kim Newton

TRENDS IN CELL BIOLOGY (2015)

Review Cell Biology

Regulated necrosis: the expanding network of non-apoptotic cell death pathways

Tom Vanden Berghe et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)

Review Immunology

TNF and MAP kinase signalling pathways

Guadalupe Sabio et al.

SEMINARS IN IMMUNOLOGY (2014)

Article Multidisciplinary Sciences

RNA-Guided Human Genome Engineering via Cas9

Prashant Mali et al.

SCIENCE (2013)

Article Multidisciplinary Sciences

Multiplex Genome Engineering Using CRISPR/Cas Systems

Le Cong et al.

SCIENCE (2013)

Article Multidisciplinary Sciences

RIP3 mediates the embryonic lethality of caspase-8-deficient mice

William J. Kaiser et al.

NATURE (2011)

Article Multidisciplinary Sciences

Catalytic activity of the caspase-8-FLIPL complex inhibits RIPK3-dependent necrosis

Andrew Oberst et al.

NATURE (2011)

Article Biochemistry & Molecular Biology

c-IAP1 and UbcH5 promote K11-linked polyubiquitination of RIP1 in TNF signalling

Jasmin N. Dynek et al.

EMBO JOURNAL (2010)

Article Biochemistry & Molecular Biology

c-IAP1 and c-IAP2 are critical mediators of tumor necrosis factor α (TNFα)-induced NF-κB activation

Eugene Varfolomeev et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2008)

Article Biochemistry & Molecular Biology

cIAP1 and cIAP2 facilitate cancer cell survival by functioning as E3 ligases that promote RIP1 ubiquitination

Mathieu J. M. Bertrand et al.

MOLECULAR CELL (2008)

Article Biochemistry & Molecular Biology

Identification of RIP1 kinase as a specific cellular target of necrostatins

Alexei Degterev et al.

NATURE CHEMICAL BIOLOGY (2008)

Article Biochemistry & Molecular Biology

IAP antagonists induce autoubiquitination of c-IAPs, NF-κB activation, and TNFα-dependent apoptosis

Eugene Varfolomeev et al.

Article Biochemistry & Molecular Biology

Ubiquitination of RIP is required for tumor necrosis factor α-induced NF-κB activation

HX Li et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2006)

Article Biochemistry & Molecular Biology

Chemical inhibitor of nonapoptotic cell death with therapeutic potential for ischemic brain injury

A Degterev et al.

NATURE CHEMICAL BIOLOGY (2005)

Article Biochemistry & Molecular Biology

Rapid generation of inducible mouse mutants -: art. no. e12

J Seibler et al.

NUCLEIC ACIDS RESEARCH (2003)