4.2 Article

Predicating the Survival of Triple-Negative Breast Cancer in Different Stages: A SEER Population Based Research Referring to Clinicopathological Factors

Journal

CANCER INVESTIGATION
Volume 38, Issue 10, Pages 549-558

Publisher

TAYLOR & FRANCIS INC
DOI: 10.1080/07357907.2020.1831010

Keywords

Triple-negative breast cancer; stage; clinicopathological factor; prognosis; SEER

Categories

Funding

  1. National Science Foundation for Young Scientists of China [81602597]
  2. Foundation Research Project of Shaanxi Province (The Natural Science Fund) [2018JM7017]

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To evaluate prognosis of breast cancer patients, a total of 16618 TNBC patients from SEER database were involved. High grade, unmarried status, tumor site were the main factors reduced OS in stage I. Black race, unmarried, large tumor size, and nodes metastasis would make worse prognosis in stage II. Compared with stage II, race and marital status had no significant effect on the prognosis in stage III. In stage IV, married status significantly improved the OS and DSS. Surgery and chemotherapy improve survival time in all of stages. Clinicopathological status correlated with the prognosis of patients with differentially staged TNBC.

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