Journal
CANADIAN JOURNAL OF OPHTHALMOLOGY-JOURNAL CANADIEN D OPHTALMOLOGIE
Volume 56, Issue 1, Pages 12-16Publisher
CANADIAN OPHTHAL SOC
DOI: 10.1016/j.jcjo.2020.07.019
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- New York Eye and Ear Foundation
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This study reports on the real-world long-term survival of primary penetrating keratoplasty in the United States, with a focus on analyzing risk factors associated with failure. The study shows a significantly lower 5-year success rate for primary PK performed for all causes compared to previously published case series in the US.
Objectives: To report real-world long-term survival of primary penetrating keratoplasty (PK) in the United States and analyze risk factors associated with failure. Design: Retrospective longitudinal cohort study using a large commercial insurance database. Participants: Ten million patients enrolled in the database from 2011 to 2017 were identified using Current Procedural Terminology codes for PK. Methods: Kaplan-Meier survival analysis was performed to determine failure rate and risk factors impacting graft outcomes. Results: Five hundred and ninety-six primary PKs were identified. The 3-year survival was 78% (confidence interval [CI]: 73%-82%), 5-year survival was 76% (CI: 70%-80%), and 7-year survival was 73% (CI: 66%-79%). Conclusion: This study demonstrated a significantly lower 5-year success rate for primary PK performed for all causes than previously published case series in the United States.
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