4.6 Article

oposSOM-Browser: an interactive tool to explore omics data landscapes in health science

Journal

BMC BIOINFORMATICS
Volume 21, Issue 1, Pages -

Publisher

BMC
DOI: 10.1186/s12859-020-03806-w

Keywords

Interactive data analysis; Transcriptomics; Results browser

Funding

  1. Projekt DEAL
  2. BMBF i:DSem (collaborative) project Leipzig Health Atlas

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BackgroundoposSOM is a comprehensive, machine learning based open-source data analysis software combining functionalities such as diversity analyses, biomarker selection, function mining, and visualization.ResultsThese functionalities are now available as interactive web-browser application for a broader user audience interested in extracting detailed information from high-throughput omics data sets pre-processed by oposSOM. It enables interactive browsing of single-gene and gene set profiles, of molecular 'portrait landscapes', of associated phenotype diversity, and signalling pathway activation patterns.ConclusionThe oposSOM-Browser makes available interactive data browsing for five transcriptome data sets of cancer (melanomas, B-cell lymphomas, gliomas) and of peripheral blood (sepsis and healthy individuals) at www.izbi.uni-leipzig.de/opossom-browser.

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