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Molecularly imprinted polymers in biological applications

Journal

BIOTECHNIQUES
Volume 69, Issue 6, Pages 407-420

Publisher

FUTURE SCI LTD
DOI: 10.2144/btn-2020-0091

Keywords

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Funding

  1. Swedish Knowledge Foundation [20160165]
  2. European Union [721297]
  3. Biofilms Research Center for Biointerfaces and Malmo University

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Molecularly imprinted polymers (MIPs) are currently widely used and further developed for biological applications. The MIP synthesis procedure is a key process, and a wide variety of protocols exist. The templates that are used for imprinting vary from the smallest glycosylated glycan structures or even amino acids to whole proteins or bacteria. The low cost, quick preparation, stability and reproducibility have been highlighted as advantages of MIPs. The biological applications utilizing MIPs discussed here include enzyme-linked assays, sensors,in vivoapplications, drug delivery, cancer diagnostics and more. Indeed, there are numerous examples of how MIPs can be used as recognition elements similar to natural antibodies.

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