4.7 Review

Side-effect management of chimeric antigen receptor (CAR) T-cell therapy

Related references

Note: Only part of the references are listed.
Article Hematology

Late Events after Treatment with CD19-Targeted Chimeric Antigen Receptor Modified T Cells

Ana Cordeiro et al.

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2020)

Article Biochemistry & Molecular Biology

Safety and feasibility of anti-CD19 CAR T cells with fully human binding domains in patients with B-cell lymphoma

Jennifer N. Brudno et al.

NATURE MEDICINE (2020)

Review Hematology

Management of toxicities associated with novel immunotherapy agents in acute lymphoblastic leukemia

Tania Jain et al.

THERAPEUTIC ADVANCES IN HEMATOLOGY (2020)

Editorial Material Multidisciplinary Sciences

Cytokine release syndrome in severe COVID-19

John B. Moore et al.

SCIENCE (2020)

Article Medicine, General & Internal

KTE-X19 CAR T-Cell Therapy in Relapsed or Refractory Mantle-Cell Lymphoma

Michael Wang et al.

NEW ENGLAND JOURNAL OF MEDICINE (2020)

Review Oncology

Management guidelines for paediatric patients receiving chimeric antigen receptor T cell therapy

Kris M. Mahadeo et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2019)

Article Biophysics

Early and late hematologic toxicity following CD19 CAR-T cells

Shalev Fried et al.

BONE MARROW TRANSPLANTATION (2019)

Article Oncology

CAR T-Cell Associated Neurotoxicity: Mechanisms, Clinicopathologic Correlates, and Future Directions

Bradley D. Hunter et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2019)

Review Health Care Sciences & Services

Current approaches in the grading and management of cytokine release syndrome after chimeric antigen receptor T-cell therapy

Lara L. Riegler et al.

THERAPEUTICS AND CLINICAL RISK MANAGEMENT (2019)

Review Immunology

Targeting Interleukin-6 Signaling in Clinic

Sujin Kang et al.

IMMUNITY (2019)

Article Oncology

Managing the toxicities of CAR T-cell therapy

Sattva S. Neelapu

HEMATOLOGICAL ONCOLOGY (2019)

Article Hematology

ASTCT Consensus Grading for Cytokine Release Syndrome and Neurologic Toxicity Associated with Immune Effector Cells

Daniel W. Lee et al.

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2019)

Article Medicine, General & Internal

Tisagenlecleucel in Adult Relapsed or Refractory Diffuse Large B-Cell Lymphoma

Stephen J. Schuster et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Article Cardiac & Cardiovascular Systems

Cardiovascular Events Among Adults Treated With Chimeric Antigen Receptor T-Cells (CAR-T)

Raza M. Alvi et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2019)

Review Oncology

Management of T-Cell Engaging Immunotherapy Complications

Indumathy Varadarajan et al.

CANCER JOURNAL (2019)

Review Oncology

Chimeric antigen receptor T-cell therapy - assessment and management of toxicities

Sattva S. Neelapu et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2018)

Letter Oncology

Hypogammaglobulinemia due to CAR T-cell therapy

Michael A. Pulsipher

PEDIATRIC BLOOD & CANCER (2018)

Article Hematology

Cardiac Profile of Chimeric Antigen Receptor T Cell Therapy in Children: A Single-Institution Experience

Danielle S. Burstein et al.

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION (2018)

Letter Critical Care Medicine

Albumin infusion improves endothelial function in septic shock patients: a pilot study

Geoffroy Hariri et al.

INTENSIVE CARE MEDICINE (2018)

Review Oncology

Grading of cytokine release syndrome associated with the CAR T cell therapy tisagenlecleucel

David Porter et al.

JOURNAL OF HEMATOLOGY & ONCOLOGY (2018)

Article Biotechnology & Applied Microbiology

Absence of Replication-Competent Lentivirus in the Clinic: Analysis of Infused T Cell Products

Kenneth Cornetta et al.

MOLECULAR THERAPY (2018)

Article Biochemistry & Molecular Biology

CAR T cell-induced cytokine release syndrome is mediated by macrophages and abated by IL-1 blockade

Theodoros Giavridis et al.

NATURE MEDICINE (2018)

Letter Oncology

Toxicity management after chimeric antigen receptor T cell therapy: one size does not fit 'ALL'

Sattva S. Neelapu et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2018)

Letter Oncology

Toxicity management after chimeric antigen receptor T cell therapy: one size does not fit 'ALL'

David T. Teachey et al.

NATURE REVIEWS CLINICAL ONCOLOGY (2018)

Review Biotechnology & Applied Microbiology

Interleukin-6: designing specific therapeutics for a complex cytokine

Christoph Garbers et al.

NATURE REVIEWS DRUG DISCOVERY (2018)

Article Medicine, General & Internal

Long-Term Follow-up of CD19 CAR Therapy in Acute Lymphoblastic Leukemia

Jae H. Park et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Medicine, General & Internal

Tisagenlecleucel in Children and Young Adults with B-Cell Lymphoblastic Leukemia

S. L. Maude et al.

NEW ENGLAND JOURNAL OF MEDICINE (2018)

Article Oncology

Chimeric Antigen Receptor T Cell-Mediated Neurotoxicity in Nonhuman Primates

Agne Taraseviciute et al.

CANCER DISCOVERY (2018)

Article Clinical Neurology

Neurotoxicity after CTL019 in a pediatric and young adult cohort

Jacqueline S. Gofshteyn et al.

ANNALS OF NEUROLOGY (2018)

Article Clinical Neurology

Neuropathology of a Case With Fatal CAR T-Cell-Associated Cerebral Edema

Matthew Torre et al.

JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY (2018)

Review Cell Biology

The biological basis and clinical symptoms of CAR-T therapy-associated toxicites

Aleksei Titov et al.

CELL DEATH & DISEASE (2018)

Article Clinical Neurology

Neurotoxicity Associated with CD19-Targeted CAR-T Cell Therapies

Juliane Gust et al.

CNS DRUGS (2018)

Article Multidisciplinary Sciences

Disruption of a self-amplifying catecholamine loop reduces cytokine release syndrome

Verena Staedtke et al.

NATURE (2018)

Article Oncology

Clinical Pharmacology of Tisagenlecleucel in B-cell Acute Lymphoblastic Leukemia

Karen Thudium Mueller et al.

CLINICAL CANCER RESEARCH (2018)

Article Medicine, Research & Experimental

Clinical and immunological responses after CD30-specific chimeric antigen receptor-redirected lymphocytes

Carlos A. Ramos et al.

JOURNAL OF CLINICAL INVESTIGATION (2017)

Article Biotechnology & Applied Microbiology

Long-Duration Complete Remissions of Diffuse Large B Cell Lymphoma after Anti-CD19 Chimeric Antigen Receptor T Cell Therapy

James N. Kochenderfer et al.

MOLECULAR THERAPY (2017)

Article Medicine, General & Internal

Chimeric Antigen Receptor T Cells in Refractory B-Cell Lymphomas

Stephen J. Schuster et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Medicine, General & Internal

Axicabtagene Ciloleucel CAR T-Cell Therapy in Refractory Large B-Cell Lymphoma

S. S. Neelapu et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Medicine, General & Internal

Blinatumomab versus Chemotherapy for Advanced Acute Lymphoblastic Leukemia

Hagop Kantarjian et al.

NEW ENGLAND JOURNAL OF MEDICINE (2017)

Article Oncology

JCAR015 in ALL: A Root-Cause Investigation

Cancer Discovery (2017)

Article Cell & Tissue Engineering

Monocyte lineage-derived IL-6 does not affect chimeric antigen receptor T-cell function

Nathan Singh et al.

CYTOTHERAPY (2017)

Article Medicine, Research & Experimental

CD19 CAR-T cells of defined CD4+: CD8+ composition in adult B cell ALL patients

Cameron J. Turtle et al.

JOURNAL OF CLINICAL INVESTIGATION (2016)

Article Biochemical Research Methods

Measuring IL-6 and sIL-6R in serum from patients treated with tocilizumab and/or siltuximab following CAR T cell therapy

Fang Chen et al.

JOURNAL OF IMMUNOLOGICAL METHODS (2016)

Article Immunology

G-CSF and GM-CSF in Neutropenia

Hrishikesh M. Mehta et al.

JOURNAL OF IMMUNOLOGY (2015)

Review Medicine, General & Internal

Fluid Resuscitation in Sepsis A Systematic Review and Network Meta-analysis

Bram Rochwerg et al.

ANNALS OF INTERNAL MEDICINE (2014)

Article Medicine, General & Internal

Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia

Shannon L. Maude et al.

NEW ENGLAND JOURNAL OF MEDICINE (2014)

Article Cell Biology

Efficacy and Toxicity Management of 19-28z CAR T Cell Therapy in B Cell Acute Lymphoblastic Leukemia

Marco L. Davila et al.

SCIENCE TRANSLATIONAL MEDICINE (2014)

Article Clinical Neurology

Chronic valproate or levetiracetam treatment does not influence cytokine levels in humans

Sabina Guenther et al.

SEIZURE-EUROPEAN JOURNAL OF EPILEPSY (2014)

Article Biotechnology & Applied Microbiology

Persistence and Efficacy of Second Generation CAR T Cell Against the LeY Antigen in Acute Myeloid Leukemia

David S. Ritchie et al.

MOLECULAR THERAPY (2013)

Article Medicine, General & Internal

Chimeric Antigen Receptor-Modified T Cells for Acute Lymphoid Leukemia

Stephan A. Grupp et al.

NEW ENGLAND JOURNAL OF MEDICINE (2013)

Article Oncology

T Cells Expressing Chimeric Antigen Receptors Can Cause Anaphylaxis in Humans

Marcela V. Maus et al.

CANCER IMMUNOLOGY RESEARCH (2013)

Review Biochemistry & Molecular Biology

IL-6 Trans-Signaling via the Soluble IL-6 Receptor: Importance for the Pro-Inflammatory Activities of IL-6

Stefan Rose-John

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2012)

Article Cell Biology

Decade-Long Safety and Function of Retroviral-Modified Chimeric Antigen Receptor T Cells

John Scholler et al.

SCIENCE TRANSLATIONAL MEDICINE (2012)

Article Medicine, General & Internal

Chimeric Antigen Receptor-Modified T Cells in Chronic Lymphoid Leukemia

David L. Porter et al.

NEW ENGLAND JOURNAL OF MEDICINE (2011)

Article Cell & Tissue Engineering

Adverse events following infusion of T cells for adoptive immunotherapy: a 10-year experience

Conrad Russell Cruz et al.

CYTOTHERAPY (2010)

Article Medicine, Research & Experimental

Gammaretrovirus-mediated correction of SCID-X1 is associated with skewed vector integration site distribution in vivo

Kerstin Schwarzwaelder et al.

JOURNAL OF CLINICAL INVESTIGATION (2007)

Review Oncology

HLH-2004: Diagnostic and therapeutic guidelines for hemophagocytic lymphohistiocytosis

Jan-Inge Henter et al.

PEDIATRIC BLOOD & CANCER (2007)

Review Biochemistry & Molecular Biology

Glucocorticoids in T cell apoptosis and function

MJ Herold et al.

CELLULAR AND MOLECULAR LIFE SCIENCES (2006)

Review Pharmacology & Pharmacy

Pharmacokinetics and pharmacodynamics of systemically administered glucocorticoids

D Czock et al.

CLINICAL PHARMACOKINETICS (2005)

Article Multidisciplinary Sciences

LMO2-associated clonal T cell proliferation in two patients after gene therapy for SCID-X1

S Hacein-Bey-Abina et al.

SCIENCE (2003)

Letter Medicine, General & Internal

A serious adverse event after successful gene therapy for X-linked severe combined immunodeficiency

S Hacein-Bey-Abina et al.

NEW ENGLAND JOURNAL OF MEDICINE (2003)