Journal
AMERICAN JOURNAL OF TRANSPLANTATION
Volume 21, Issue 1, Pages 15-20Publisher
ELSEVIER SCIENCE INC
DOI: 10.1111/ajt.16282
Keywords
artificial organs/support devices; lung; clinical research; practice; lung disease; congenital; lung transplantation/pulmonology; pediatrics; surgical technique
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Lung transplantation in infants presents unique challenges due to the scarcity of data in this age group compared to older children and adults. Recent advances in bridge-to-transplantation therapy and differences in surgical techniques have been studied to provide the best care for infant patients undergoing lung transplantation.
Lung transplantation is a crucial component in the treatment of end-stage lung disease in infants. Traditionally, most lung transplants have been performed in older children and adults, resulting in a scarcity of data for infant patients. To address the challenges unique to this age group, novel strategies to provide the best preoperative, intraoperative, and postoperative care for these youngest patients are paramount. We review recent advances in bridge-to-transplantation therapy, including the use of a paracorporeal lung assist device, and differences in surgical technique, including bronchial artery revascularization, for incorporation into the overarching treatment strategy for infants undergoing lung transplantation.
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