4.5 Review

Microbiota in Rosacea

Journal

AMERICAN JOURNAL OF CLINICAL DERMATOLOGY
Volume 21, Issue SUPPL 1, Pages 25-35

Publisher

ADIS INT LTD
DOI: 10.1007/s40257-020-00546-8

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Funding

  1. National Research Foundation of Korea (NRF) - South Korean Government [2017R1C1B5016144, 2020R1F1A1048238]
  2. National Research Foundation of Korea [2020R1F1A1048238, 2017R1C1B5016144] Funding Source: Korea Institute of Science & Technology Information (KISTI), National Science & Technology Information Service (NTIS)

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Rosacea is a complex facial skin condition associated with abnormal inflammation and vascular dysfunction. Next to the known trigger factors, the role of microbiota in the development and aggravation of rosacea continues to raise interest.Demodex folliculorummites,Helicobacter pylori,Staphylococcus epidermidis,Chlamydia pneumoniae,and theDemodex-associated bacterium,Bacillus oleroniusare microbes that have been linked with rosacea. However, the results of studies which assessed their involvement in the disease have been inconsistent and inconclusive. Microbiological research in many different disciplines exploded in recent years as methods to analyze complex microbial communities at the taxonomic and phylogenetic levels became available. Here, we provide an update on the microorganisms implicated in rosacea and review the potential pathogenic role of microbes in the development of rosacea.

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