Related references
Note: Only part of the references are listed.The KCa2 Channel Inhibitor AP30663 Selectively Increases Atrial Refractoriness, Converts Vernakalant-Resistant Atrial Fibrillation and Prevents Its Reinduction in Conscious Pigs
Jonas Goldin Diness et al.
FRONTIERS IN PHARMACOLOGY (2020)
Gain-of-Function Mutations in KCNN3 Encoding the Small-Conductance Ca2+-Activated K+ Channel SK3 Cause Zimmermann-Laband Syndrome
Christiane K. Bauer et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2019)
The Trials and Tribulations of Structure Assisted Design of KCa Channel Activators
Heesung Shim et al.
FRONTIERS IN PHARMACOLOGY (2019)
SKA-31, an activator of endothelial Ca2+-activated K+ channels evokes robust vasodilation in rat mesenteric arteries
Rayan Khaddaj-Mallat et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2018)
Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures
Chia-Hsueh Lee et al.
SCIENCE (2018)
A V-to-F substitution in SK2 channels causes Ca2+ hypersensitivity and improves locomotion in a C-elegans ALS model
Young-Woo Nam et al.
SCIENTIFIC REPORTS (2018)
A new negative allosteric modulator, AP14145, for the study of small conductance calcium-activated potassium (KCa2) channels
Rafel Simo-Vicens et al.
BRITISH JOURNAL OF PHARMACOLOGY (2017)
Tremor dominant Kyoto (Trdk) rats carry a missense mutation in the gene encoding the SK2 subunit of small-conductance Ca2+-activated K+ channel
Takashi Kuramoto et al.
BRAIN RESEARCH (2017)
In vivo analysis of cerebellar Purkinje cell activity in SCA2 transgenic mouse model
Polina A. Egorova et al.
JOURNAL OF NEUROPHYSIOLOGY (2016)
A pharmacologic activator of endothelial KCa channels increases systemic conductance and reduces arterial pressure in an anesthetized pig model
Ramesh C. Mishra et al.
VASCULAR PHARMACOLOGY (2016)
A mutation in the Gardos channel is associated with hereditary xerocytosis
Raphael Rapetti-Mauss et al.
BLOOD (2015)
Riluzole in patients with hereditary cerebellar ataxia: a randomised, double-blind, placebo-controlled trial
Silvia Romano et al.
LANCET NEUROLOGY (2015)
Selective phosphorylation modulates the PIP2 sensitivity of the CaM-SK channel complex
Miao Zhang et al.
NATURE CHEMICAL BIOLOGY (2014)
Alterations in cerebellar physiology are associated with a stiff-legged gait in Atcayji-hes mice
Katiuska Luna-Cancalon et al.
NEUROBIOLOGY OF DISEASE (2014)
Activation of K(Ca)3.1 by SKA-31 induces arteriolar dilatation and lowers blood pressure in normo- and hypertensive connexin40-deficient mice
Josephine Radtke et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
The Neuroprotective Drug Riluzole Acts via Small Conductance Ca2+-Activated K+ Channels to Ameliorate Defects in Spinal Muscular Atrophy Models
Maria Dimitriadi et al.
JOURNAL OF NEUROSCIENCE (2013)
Unstructured to structured transition of an intrinsically disordered protein peptide in coupling Ca2+-sensing and SK channel activation
Miao Zhang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Small-Conductance Ca2+-Activated K+ Channels: Form and Function
John P. Adelman et al.
ANNUAL REVIEW OF PHYSIOLOGY, VOL 74 (2012)
Selective Positive Modulator of Calcium-Activated Potassium Channels Exerts Beneficial Effects in a Mouse Model of Spinocerebellar Ataxia Type 2
Adebimpe W. Kasumu et al.
CHEMISTRY & BIOLOGY (2012)
Cerebellar Ataxia by Enhanced CaV2.1 Currents Is Alleviated by Ca2+-Dependent K+-Channel Activators in Cacna1aS218L Mutant Mice
Zhenyu Gao et al.
JOURNAL OF NEUROSCIENCE (2012)
Structural Basis for Calmodulin as a Dynamic Calcium Sensor
Miao Zhang et al.
STRUCTURE (2012)
Identification of the functional binding pocket for compounds targeting small-conductance Ca2+-activated potassium channels
Miao Zhang et al.
NATURE COMMUNICATIONS (2012)
Early Changes in Cerebellar Physiology Accompany Motor Dysfunction in the Polyglutamine Disease Spinocerebellar Ataxia Type 3
Vikram G. Shakkottai et al.
JOURNAL OF NEUROSCIENCE (2011)
Vascular KCa-channels as therapeutic targets in hypertension and restenosis disease
Ralf Kohler et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2010)
The Therapeutic Mode of Action of 4-Aminopyridine in Cerebellar Ataxia
Karina Alvina et al.
JOURNAL OF NEUROSCIENCE (2010)
KCa Channels as Therapeutic Targets in Episodic Ataxia Type-2
Karina Alvina et al.
JOURNAL OF NEUROSCIENCE (2010)
Riluzole in cerebellar ataxia A randomized, double-blind, placebo-controlled pilot trial
G. Ristori et al.
NEUROLOGY (2010)
Modulation of the activity of dopaminergic neurons by SK channels: a potential target for the treatment of Parkinson's disease?
Xiao-Kun Liu et al.
NEUROSCIENCE BULLETIN (2010)
Conserved Genes Act as Modifiers of Invertebrate SMN Loss of Function Defects
Maria Dimitriadi et al.
PLOS GENETICS (2010)
EF hands at the N-lobe of calmodulin are required for both SK channel gating and stable SK-calmodulin interaction
Weiyan Li et al.
JOURNAL OF GENERAL PHYSIOLOGY (2009)
Naphtho[1,2-d]thiazol-2-ylamine (SKA-31), a New Activator of KCa2 and KCa3.1 Potassium Channels, Potentiates the Endothelium-Derived Hyperpolarizing Factor Response and Lowers Blood Pressure
Ananthakrishnan Sankaranarayanan et al.
MOLECULAR PHARMACOLOGY (2009)
Molecular and cellular basis of small- and intermediate-conductance, calcium-activated potassium channel function in the brain
P. Pedarzani et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2008)
GROMACS 4: Algorithms for highly efficient, load-balanced, and scalable molecular simulation
Berk Hess et al.
JOURNAL OF CHEMICAL THEORY AND COMPUTATION (2008)
Selective positive modulation of the SK3 and SK2 subtypes of small conductance Ca2+-activated K+ channels
C. Hougaard et al.
BRITISH JOURNAL OF PHARMACOLOGY (2007)
Organization and regulation of small conductance Ca2+-activated K+ channel multiprotein complexes
Duane Allen et al.
JOURNAL OF NEUROSCIENCE (2007)
Inhibitory gating modulation of small conductance Ca2+-activated K+ channels by the synthetic compound (R)-N-(benzimidazol-2-yl)-1,2,3,4-tetrahydro-1-naphtylamine (NS8593) reduces afterhyperpolarizing current in hippocampal CA1 neurons
Dorte Strobaek et al.
MOLECULAR PHARMACOLOGY (2006)
Evidence for involvement of both IKCa and SKCa channels in hyperpolarizing responses of the rat middle cerebral artery
AJ McNeish et al.
STROKE (2006)
Decreases in the precision of Purkinje cell pacemaking cause cerebellar dysfunction and ataxia
JT Walter et al.
NATURE NEUROSCIENCE (2006)
Possible role for K+ in endothelium-derived hyperpolarizing factor-linked dilatation in rat middle cerebral artery
AJ McNeish et al.
STROKE (2005)
Protein kinase CK2 is coassembled with small conductance Ca2+-activated K+ channels and regulates channel gating
W Bildl et al.
NEURON (2004)
Ca2+-activated K+ channels:: Molecular determinants and function of the SK family
M Stocker
NATURE REVIEWS NEUROSCIENCE (2004)
Role of endothelial intermediate conductance KCa channels in cerebral EDHF-mediated dilations
SP Marrelli et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2003)
Structure of the gating domain of a Ca2+-activated K+ channel complexed with Ca2+/calmodulin
MA Schumacher et al.
NATURE (2001)
Control of electrical activity in central neurons by modulating the gating of small conductance Ca2+-activated K+ channels
P Pedarzani et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Structure and complex transcription pattern of the mouse SK1KCa channel gene, KCNN1
BE Shmukler et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION (2001)