Journal
DIAGNOSTICS
Volume 10, Issue 8, Pages -Publisher
MDPI
DOI: 10.3390/diagnostics10080568
Keywords
ovarian cancer cytoreduction; neoadjuvant chemotherapy; preoperative predictors of optimal tumor cytoreduction
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Ovarian cancer is the deadliest gynecologic cancer, in part due to late presentation. Many women have vague early symptoms and present with disseminated disease. Cytoreductive surgery can be extensive, involving multiple organ systems. Novel therapies and recent clinical trials have provided evidence that, compared to primary cytoreduction, neoadjuvant chemotherapy has equivalent survival outcomes with less morbidity. There is increasing need for validated tools and mechanisms for clinicians to determine the optimal management of ovarian cancer patients.
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