Journal
METABOLITES
Volume 10, Issue 6, Pages -Publisher
MDPI
DOI: 10.3390/metabo10060264
Keywords
inflammation; lipid mediators; lipidomics; metabolites; metabolomics; physical exercise
Categories
Funding
- Sao Paulo Research Foundation-FAPESP [2016/222157, 2018/250823]
Ask authors/readers for more resources
Oxylipins are oxidized compounds of polyunsaturated fatty acids that play important roles in the body. Recently, metabololipidomic-based studies using advanced mass spectrometry have measured the oxylipins generated during acute and chronic physical exercise and described the related physiological effects. The objective of this systematic review was to provide a panel of the primary exercise-related oxylipins and their respective functions in healthy individuals. Searches were performed in five databases (Cochrane, PubMed, Science Direct, Scopus and Web of Science) using combinations of the Medical Subject Headings (MeSH) terms: Humans, Exercise, Physical Activity, Sports, Oxylipins, and Lipid Mediators. An adapted scoring system created in a previous study from our group was used to rate the quality of the studies. Nine studies were included after examining 1749 documents. Seven studies focused on the acute effect of physical exercise while two studies determined the effects of exercise training on the oxylipin profile. Numerous oxylipins are mobilized during intensive and prolonged exercise, with most related to the inflammatory process, immune function, tissue repair, cardiovascular and renal functions, and oxidative stress.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available